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WormBase Tree Display for Gene: WBGene00002278

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Name Class

WBGene00002278SMapS_parentSequenceY55F3AM
IdentityVersion2
NameCGC_namelep-2Person_evidenceWBPerson178
Sequence_nameY55F3AM.6
Molecular_nameY55F3AM.6a
Y55F3AM.6a.1
CE25488
Y55F3AM.6b
CE33891
Y55F3AM.6b.1
Other_nameCELE_Y55F3AM.6Accession_evidenceNDBBX284604
Public_namelep-2
DB_infoDatabaseNDBlocus_tagCELE_Y55F3AM.6
PanthergeneCAEEL|WormBase=WBGene00002278|UniProtKB=Q9N373
familyPTHR11224
NCBIgene176918
RefSeqproteinNM_001028339.6
NM_001028340.6
KEGGKEGG_id2.3.2.27
NemaPathKEGG_id2.3.2.27
SwissProtUniProtAccQ9N373
TREEFAMTREEFAM_IDTF315108
UniProt_GCRPUniProtAccQ9N373
OMIMgene603856
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:27WBPerson1971EventImportedInitial conversion from geneace
227 Jan 2017 11:53:13WBPerson2970EventAcquires_mergeWBGene00021924
Acquires_mergeWBGene00021924
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classlep
Allele (140)
Legacy_information[C.elegansII] bx73 : mail tail tip protrudes beyond posterior edge of fan, failure of tail tip syncytium retraction. NA1. [DF]
StrainWBStrain00031696
WBStrain00054733
RNASeq_FPKM (74)
GO_annotation (13)
Contained_in_operonCEOP4044
Ortholog (52)
ParalogWBGene00014772Caenorhabditis elegansFrom_analysismodENCODE_Pseudogenes
Structured_descriptionAutomated_descriptionPredicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. Predicted to be located in cytoplasm. Expressed in developing hermaphrodite gonad; hypodermis; neurons; and pharynx. Human ortholog(s) of this gene implicated in central precocious puberty 2. Is an ortholog of several human genes including MKRN1 (makorin ring finger protein 1); MKRN3 (makorin ring finger protein 3); and MKRN4P (makorin ring finger protein 4, pseudogene).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0112309Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7114)
Molecular_infoCorresponding_CDSY55F3AM.6a
Y55F3AM.6b
Corresponding_transcriptY55F3AM.6a.1
Y55F3AM.6b.1
Other_sequence (20)
Associated_featureWBsf645777
WBsf978624
WBsf995314
WBsf995315
WBsf1016642
WBsf227900
WBsf227901
WBsf227902
WBsf227903
Transcription_factorWBTranscriptionFactor001105
Experimental_infoRNAi_resultWBRNAi00057532Inferred_automaticallyRNAi_primary
WBRNAi00094794Inferred_automaticallyRNAi_primary
WBRNAi00015826Inferred_automaticallyRNAi_primary
WBRNAi00037520Inferred_automaticallyRNAi_primary
WBRNAi00021028Inferred_automaticallyRNAi_primary
WBRNAi00076826Inferred_automaticallyRNAi_primary
Expr_patternExpr12704
Expr1027160
Expr1039637
Expr1160966
Expr2013048
Expr2031280
Drives_constructWBCnstr00022657
Construct_productWBCnstr00022657
Microarray_results (27)
Expression_cluster (75)
InteractionWBInteraction000505323
WBInteraction000526650
WBInteraction000527767
WBInteraction000528073
WBInteraction000549123
WBInteraction000559648
WBInteraction000560390
WBInteraction000582668
Map_infoMapIVPosition-22.7898
PositivePositive_cloneY55F3AMInferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (15)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene