WormBase Tree Display for Gene: WBGene00002238
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| WBGene00002238 | SMap | S_parent | Sequence | T02G5 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | kars-1 | Person_evidence | WBPerson36 | |||||
| WBPerson10953 | |||||||||
| Sequence_name | T02G5.9 | ||||||||
| Molecular_name | T02G5.9a | ||||||||
| T02G5.9a.1 | |||||||||
| CE04861 | |||||||||
| T02G5.9b | |||||||||
| CE28247 | |||||||||
| T02G5.9b.1 | |||||||||
| Other_name | krs-1 | ||||||||
| CELE_T02G5.9 | Accession_evidence | NDB | BX284602 | ||||||
| Public_name | kars-1 | ||||||||
| DB_info | Database (14) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:27 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 29 Jan 2010 14:16:16 | WBPerson2970 | Name_change | CGC_name | kars-1 | ||||
| Other_name | krs-1 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | kars | ||||||||
| Allele (20) | |||||||||
| Strain | WBStrain00051411 | ||||||||
| WBStrain00055524 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (29) | |||||||||
| Ortholog (37) | |||||||||
| Paralog | WBGene00001094 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
| WBGene00001095 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00003815 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00013447 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Automated_description | Predicted to enable lysine-tRNA ligase activity and tRNA binding activity. Involved in several processes, including determination of adult lifespan; positive regulation of nematode larval development; and regulation of brood size. Predicted to be located in cytosol and mitochondrion. Predicted to be part of aminoacyl-tRNA synthetase multienzyme complex. Expressed in tail. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease recessive intermediate B and autosomal recessive nonsyndromic deafness 89. Is an ortholog of human KARS1 (lysyl-tRNA synthetase 1). | Paper_evidence | WBPaper00065943 | |||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0110534 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6215) | ||||
| DOID:0110204 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6215) | ||||||
| Molecular_info | Corresponding_CDS | T02G5.9a | |||||||
| T02G5.9b | |||||||||
| Corresponding_CDS_history | T02G5.9:wp54 | ||||||||
| T02G5.9c:wp275 | |||||||||
| Corresponding_transcript | T02G5.9a.1 | ||||||||
| T02G5.9b.1 | |||||||||
| Other_sequence (171) | |||||||||
| Associated_feature | WBsf223284 | ||||||||
| WBsf223285 | |||||||||
| WBsf223286 | |||||||||
| Experimental_info | RNAi_result (48) | ||||||||
| Expr_pattern | Chronogram1293 | ||||||||
| Expr6574 | |||||||||
| Expr1015777 | |||||||||
| Expr1031313 | |||||||||
| Expr1155864 | |||||||||
| Expr2012901 | |||||||||
| Expr2031135 | |||||||||
| Drives_construct | WBCnstr00003497 | ||||||||
| WBCnstr00037958 | |||||||||
| Construct_product | WBCnstr00037958 | ||||||||
| Microarray_results (45) | |||||||||
| Expression_cluster (164) | |||||||||
| Interaction (184) | |||||||||
| Map_info | Map | II | Position | 0.484121 | Error | 0.003572 | |||
| Positive | Positive_clone | T02G5 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00038491 | ||||||||
| WBPaper00049828 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | dl1 : probably cytoplasmic | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
