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WormBase Tree Display for Gene: WBGene00002190

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Name Class

WBGene00002190SMapS_parentSequenceR07E4
IdentityVersion1
NameCGC_namekin-2
Sequence_nameR07E4.6
Molecular_nameR07E4.6a
R07E4.6a.1
CE39609
R07E4.6b
CE28749
R07E4.6c
CE04821
R07E4.6b.1
R07E4.6c.1
Other_nameCELE_R07E4.6Accession_evidenceNDBBX284606
Public_namekin-2
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:27WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classkin
Allele (122)
Legacy_information[C.elegansII] NMK. Encodes regulatory subunit of cAMP-dependentprotein kinase (clone CR#LRI1)[CR]
StrainWBStrain00023482
WBStrain00036114
RNASeq_FPKM (74)
GO_annotation (17)
Ortholog (41)
Structured_descriptionConcise_descriptionkin-2 encodes a predicted regulatory subunit of a cAMP-dependent protein kinase that may act downstream of, or in parallel to, ric-8.Paper_evidenceWBPaper00001250
WBPaper00016794
WBPaper00018903
Curator_confirmedWBPerson48
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable cAMP-dependent protein kinase regulator activity. Involved in several processes, including medium-term memory; negative regulation of oocyte maturation; and negative regulation of protein kinase C signaling. Located in cytosol and membrane. Part of cAMP-dependent protein kinase complex. Expressed in body wall musculature; hypodermis; and intestine. Human ortholog(s) of this gene implicated in Carney complex; acrodysostosis; and primary pigmented nodular adrenocortical disease. Is an ortholog of human PRKAR1B (protein kinase cAMP-dependent type I regulatory subunit beta).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:14669Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9388)
DOID:0060280Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9388)
DOID:0050471Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9388)
Molecular_infoCorresponding_CDSR07E4.6a
R07E4.6b
R07E4.6c
Corresponding_CDS_historyR07E4.6a:wp153
Corresponding_transcriptR07E4.6a.1
R07E4.6b.1
R07E4.6c.1
Other_sequence (210)
Associated_feature (21)
Experimental_infoRNAi_result (28)
Expr_patternExpr8555
Expr8556
Expr13011
Expr1017206
Expr1031283
Expr1155162
Expr2012938
Expr2031170
Drives_constructWBCnstr00036400
WBCnstr00038145
Construct_productWBCnstr00018370
WBCnstr00018371
WBCnstr00036400
AntibodyWBAntibody00001761
WBAntibody00001762
Microarray_results (37)
Expression_cluster (163)
Interaction (235)
WBProcessWBbiopr:00000120
Map_infoMapXPosition-3.97543Error0.014707
PositivePositive_cloneCR#LRI1
R07E4Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4443
4456
Pseudo_map_position
Reference (58)
PictureWBPicture0000013094
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene