WormBase Tree Display for Gene: WBGene00002190

WBGene00002190 SMap: S_parent: Sequence: R07E4
  Identity: Version: 1
    Name: CGC_name: kin-2
      Sequence_name: R07E4.6
      Molecular_name: R07E4.6a
        R07E4.6a.1
        CE39609
        R07E4.6b
        CE28749
        R07E4.6c
        CE04821
        R07E4.6b.1
        R07E4.6c.1
      Other_name: CELE_R07E4.6 Accession_evidence: NDB BX284606
      Public_name: kin-2
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:27 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: kin
    Allele: WBVar00053977 Inferred_automatically: From strain object: KG532
      WBVar02159255
      WBVar00309451
      WBVar00505033
      WBVar00505034
      WBVar00505035
      WBVar00505036
      WBVar00505037
      WBVar01487021
      WBVar00505038
      WBVar00505039
      WBVar00505040
      WBVar00505041
      WBVar02056371
      WBVar00505042
      WBVar02056372
      WBVar00505043
      WBVar00505044
      WBVar00505045
      WBVar00505046
      WBVar00505047
      WBVar01945491
      WBVar00505048
      WBVar01945492
      WBVar00505049
      WBVar00505050
      WBVar02147677
      WBVar00097289
      WBVar00097290
      WBVar01151080
      WBVar01151081
      WBVar01151082
      WBVar01151083
      WBVar01151084
      WBVar01151085
      WBVar01151086
      WBVar01151087
      WBVar01151088
      WBVar00235844
      WBVar01880403
      WBVar00235845
      WBVar01151089
      WBVar01880404
      WBVar01151090
      WBVar01880405
      WBVar01151091
      WBVar01880406
      WBVar01151092
      WBVar01880407
      WBVar01880408
      WBVar01151093
      WBVar01880409
      WBVar01151094
      WBVar01880410
      WBVar01151095
      WBVar01880411
      WBVar01151096
      WBVar01880412
      WBVar01151097
      WBVar01151098
      WBVar01880413
      WBVar01151099
      WBVar01880414
      WBVar01151100
      WBVar01880415
      WBVar01550078
      WBVar01880416
      WBVar01151101
      WBVar01926847
      WBVar01151102
      WBVar01926848
      WBVar01151103
      WBVar01926849
      WBVar01151104
      WBVar01926850
      WBVar01151105
      WBVar01151106
      WBVar01151107
      WBVar01151108
      WBVar01151109
      WBVar01151110
      WBVar01151111
      WBVar01151112
      WBVar01151113
      WBVar01151114
      WBVar01151115
      WBVar01151116
      WBVar00026976
      WBVar01151117
      WBVar01987407
      WBVar01151118
      WBVar01151119
      WBVar00026981
      WBVar01151120
      WBVar01151121
      WBVar00026986
      WBVar00026991
      WBVar00026996
      WBVar02027161
      WBVar01499262
      WBVar01980759
      WBVar01758557
      WBVar01758558
      WBVar01499283
      WBVar01499284
      WBVar02083378
      WBVar01469147
      WBVar01469148
      WBVar02139379
      WBVar02139380
      WBVar01820029
      WBVar02139381
      WBVar00249668
      WBVar02009046
      WBVar02064076
      WBVar00091551
      WBVar02064077
      WBVar02064078
      WBVar02064079
      WBVar00079524
      WBVar02064080
      WBVar01500067
    Legacy_information: [C.elegansII] NMK. Encodes regulatory subunit of cAMP-dependentprotein kinase (clone CR#LRI1)[CR]
    Strain: WBStrain00023482
      WBStrain00036114
    RNASeq_FPKM (74)
    GO_annotation (17)
    Ortholog (41)
    Structured_description: Concise_description: kin-2 encodes a predicted regulatory subunit of a cAMP-dependent protein kinase that may act downstream of, or in parallel to, ric-8. Paper_evidence: WBPaper00001250
            WBPaper00016794
            WBPaper00018903
          Curator_confirmed: WBPerson48
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable cAMP-dependent protein kinase regulator activity. Involved in several processes, including medium-term memory; negative regulation of oocyte maturation; and negative regulation of protein kinase C signaling. Located in cytosol and membrane. Part of cAMP-dependent protein kinase complex. Expressed in body wall musculature; hypodermis; and intestine. Human ortholog(s) of this gene implicated in Carney complex; acrodysostosis; and primary pigmented nodular adrenocortical disease. Is an ortholog of human PRKAR1B (protein kinase cAMP-dependent type I regulatory subunit beta). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:14669 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:9388)
      DOID:0060280 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:9388)
      DOID:0050471 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:9388)
  Molecular_info: Corresponding_CDS: R07E4.6a
      R07E4.6b
      R07E4.6c
    Corresponding_CDS_history: R07E4.6a:wp153
    Corresponding_transcript: R07E4.6a.1
      R07E4.6b.1
      R07E4.6c.1
    Other_sequence (210)
    Associated_feature (21)
  Experimental_info: RNAi_result (28)
    Expr_pattern: Expr8555
      Expr8556
      Expr13011
      Expr1017206
      Expr1031283
      Expr1155162
      Expr2012938
      Expr2031170
    Drives_construct: WBCnstr00036400
      WBCnstr00038145
    Construct_product: WBCnstr00018370
      WBCnstr00018371
      WBCnstr00036400
    Antibody: WBAntibody00001761
      WBAntibody00001762
    Microarray_results (37)
    Expression_cluster (163)
    Interaction (235)
    WBProcess: WBbiopr:00000120
  Map_info: Map: X Position: -3.97543 Error: 0.014707
    Positive: Positive_clone: CR#LRI1
        R07E4 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4443
        4456
    Pseudo_map_position
  Reference (58)
  Picture: WBPicture0000013094
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene