WormBase Tree Display for Gene: WBGene00002163

WBGene00002163 SMap: S_parent: Sequence: CHROMOSOME_X
  Identity: Version: 2
    Name: CGC_name: ist-1 Person_evidence: WBPerson545
      Sequence_name: C54D1.3
      Molecular_name (12)
      Other_name: CELE_C54D1.3 Accession_evidence: NDB BX284606
      Public_name: ist-1
    DB_info: Database (8)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:26 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 01 Jul 2016 14:56:15 WBPerson1983 Event: Acquires_merge: WBGene00044576
      Acquires_merge: WBGene00044576
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: ist
    Allele: WBVar01945648
      WBVar02064653
      WBVar02064654
      WBVar01158769
      WBVar00236341
      WBVar01158770
      WBVar01158771
      WBVar01158772
      WBVar01158773
      WBVar01158774
      WBVar01158775
      WBVar01158776
      WBVar01158777
      WBVar01158778
      WBVar01489229
      WBVar01158779
      WBVar01158780
      WBVar01158781
      WBVar01158782
      WBVar01158783
      WBVar01782254
      WBVar02153665
      WBVar01158784
      WBVar01158785
      WBVar01849016
      WBVar01158786
      WBVar01849017
      WBVar01158787
      WBVar01849018
      WBVar02151634
      WBVar01849019
      WBVar01158788
      WBVar01158789
      WBVar01158790
      WBVar01158791
      WBVar01158792
      WBVar01158793
      WBVar01158794
      WBVar01158795
      WBVar01158796
      WBVar01882951
      WBVar01882952
      WBVar01158797
      WBVar01882953
      WBVar01158798
      WBVar01882954
      WBVar01158799
      WBVar01882955
      WBVar01158800
      WBVar01882956
      WBVar01158801
      WBVar01158802
      WBVar01882957
      WBVar01158803
      WBVar01882958
      WBVar01158804
      WBVar01882959
      WBVar01158805
      WBVar01882960
      WBVar01882961
      WBVar01158806
      WBVar01882962
      WBVar01158807
      WBVar01158808
      WBVar01882963
      WBVar01158809
      WBVar01882964
      WBVar01882965
      WBVar01158810
      WBVar01882966
      WBVar01158811
      WBVar01882967
      WBVar01158812
      WBVar02056401
      WBVar01158813
      WBVar01882968
      WBVar01980874
      WBVar01158814
      WBVar01882969
      WBVar01980875
      WBVar01158815
      WBVar01882970
      WBVar01882971
      WBVar01980876
      WBVar01158816
      WBVar01882972
      WBVar01980877
      WBVar01158817
      WBVar01158818
      WBVar01882973
      WBVar01882974
      WBVar01158819
      WBVar01882975
      WBVar01158820
      WBVar01499760
      WBVar01158821
      WBVar01882976
      WBVar01882977
      WBVar01499761
      WBVar01158822
      WBVar01158823
      WBVar01882978
      WBVar01158824
      WBVar01882979
      WBVar01158825
      WBVar01882980
      WBVar01882981
      WBVar01158826
      WBVar01882982
      WBVar01158827
      WBVar01158828
      WBVar01882983
      WBVar01882984
      WBVar01158829
      WBVar01882985
      WBVar01158830
      WBVar01158831
      WBVar01882986
      WBVar01882987
      WBVar01158832
      WBVar01158833
      WBVar01882988
      WBVar01835702
      WBVar01158834
      WBVar01882989
      WBVar01882990
      WBVar01158835
      WBVar01158836
      WBVar01158837
      WBVar01158838
      WBVar01158839
      WBVar01158840
      WBVar01158841
      WBVar01601903
      WBVar01601904
      WBVar01158842
      WBVar01158843
      WBVar01758693
      WBVar01158844
      WBVar01158845
      WBVar01815906
      WBVar01758694
      WBVar01158846
      WBVar01815907
      WBVar01158847
      WBVar01158848
      WBVar01158849
      WBVar01158850
      WBVar01158851
      WBVar01158852
      WBVar00507702
      WBVar00507703
      WBVar01550478
      WBVar02116473
      WBVar02116474
      WBVar00507704
      WBVar00507705
      WBVar00507706
      WBVar00507707
      WBVar00507708
      WBVar00507709
      WBVar00507710
      WBVar00507711
      WBVar00507712
      WBVar00507713
      WBVar00507714
      WBVar00507715
      WBVar00507716
      WBVar00507717
      WBVar00098936
      WBVar00507718
      WBVar00507719
      WBVar00507720
      WBVar00507721
      WBVar00507722
      WBVar00507723
      WBVar00507724
      WBVar00507725
      WBVar00507726
      WBVar00507727
      WBVar00507728
      WBVar00507729
      WBVar00507730
      WBVar00047216
      WBVar00507731
      WBVar00507732
      WBVar00047221
      WBVar00507733
      WBVar00507734
      WBVar00507735
      WBVar00507736
      WBVar00507737
      WBVar02027197
      WBVar02027198
      WBVar00047231
      WBVar00047236
      WBVar01820213
      WBVar01830770
      WBVar00080281
      WBVar01830771
      WBVar00047241
      WBVar00080282
      WBVar02013649
      WBVar00080283
      WBVar00047246
      WBVar00080286
      WBVar00080288
      WBVar02083396
      WBVar00047251
      WBVar00047256
      WBVar00093809
      WBVar00047261
      WBVar00047266
      WBVar00047271
      WBVar01487170
      WBVar01499685
      WBVar00047276
      WBVar00047281
      WBVar01498586
      WBVar01927129
      WBVar01927130
      WBVar02064644
      WBVar01469647
      WBVar01469648
      WBVar02064645
      WBVar02064646
      WBVar02064647
      WBVar02064648
      WBVar02064649
      WBVar02064650
      WBVar02064651
      WBVar01500067
      WBVar02064652
    Strain: WBStrain00033295
      WBStrain00037950
    RNASeq_FPKM (74)
    GO_annotation: 00062458
      00062459
      00062460
      00062461
      00062462
      00062463
    Ortholog (28)
    Structured_description: Concise_description: ist-1 encodes a pleckstrin homology (PH) and phosphotyrosine binding (PTB) domain-containing insulin receptor substrate (IRS) homolog that negatively regulates lifespan and dauer development; IST-1 potentiates insulin-like signaling, although it is not absolutely required for such signaling under most conditions; in addition to acting through the AGE-1/PI3K branch of the insulin-like signaling pathway, IST-1 may also function in a parallel pathway to activate downstream protein-kinase Bs encoded by akt-1 and akt-2. Paper_evidence: WBPaper00005614
          Curator_confirmed: WBPerson1843
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable insulin receptor binding activity; phosphatidylinositol 3-kinase binding activity; and transmembrane receptor protein tyrosine kinase adaptor activity. Involved in dauer larval development; insulin receptor signaling pathway; and short-term memory. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C54D1.3b
      C54D1.3c
      C54D1.3d
      C54D1.3e
    Corresponding_CDS_history: C54D1.3:wp128
      C54D1.3b:wp271
      C54D1.3c:wp271
    Corresponding_transcript: C54D1.3b.1
      C54D1.3c.1
      C54D1.3d.1
      C54D1.3e.1
    Other_sequence: Tcir_isotig31452
      Tcir_isotig15722
    Associated_feature (14)
  Experimental_info: RNAi_result (12)
    Expr_pattern: Expr1012662
      Expr1025581
      Expr1031266
      Expr1146049
      Expr1147097
      Expr2012871
      Expr2031105
    Drives_construct: WBCnstr00023456
      WBCnstr00036412
    Construct_product: WBCnstr00023456
      WBCnstr00036412
    Microarray_results (28)
    Expression_cluster (196)
    Interaction (12)
  Map_info: Map: X Position: -1.82954 Error: 0.004648
    Positive: Positive_clone: C54D1 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (13)
  Remark: Sequence connection from [Wolkow C]
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene