WormBase Tree Display for Gene: WBGene00002070

WBGene00002070 Evidence: Person_evidence: WBPerson842
  SMap: S_parent: Sequence: K07A1
  Identity: Version: 1
    Name: CGC_name: ile-1 Person_evidence: WBPerson842
      Sequence_name: K07A1.8
      Molecular_name: K07A1.8
        K07A1.8.1
        CE11854
      Other_name: CELE_K07A1.8 Accession_evidence: NDB BX284601
      Public_name: ile-1
    DB_info: Database: AceView gene 1K186
        WormQTL gene WBGene00002070
        WormFlux gene WBGene00002070
        NDB locus_tag CELE_K07A1.8
        Panther gene CAEEL|WormBase=WBGene00002070|UniProtKB=G5EDE8
          family PTHR12223
        NCBI gene 172799
        RefSeq protein NM_060147.7
        TREEFAM TREEFAM_ID TF313311
        TrEMBL UniProtAcc G5EDE8
        UniProt_GCRP UniProtAcc G5EDE8
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:26 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: ile
    Allele (33)
    Strain: WBStrain00055467
    RNASeq_FPKM (74)
    GO_annotation: 00013889
      00013890
      00013891
      00013892
      00013893
      00013894
      00013895
      00105739
      00109967
    Ortholog (44)
    Paralog: WBGene00002071 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Concise_description: ile-1 is orthologous to the human gene human ERGIC-53, which when mutated leads to deficiency of coagulation factors V/VIII (OMIM:227300). Paper_evidence: WBPaper00004103
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable mannose binding activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in factor V deficiency and factor XIII deficiency. Is an ortholog of human LMAN1 (lectin, mannose binding 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:2211 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6631)
      DOID:2216 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6631)
  Molecular_info: Corresponding_CDS: K07A1.8
    Corresponding_transcript: K07A1.8.1
    Other_sequence (64)
    Associated_feature: WBsf649498
      WBsf664767
      WBsf976906
      WBsf976907
      WBsf976908
      WBsf976909
      WBsf984761
      WBsf220109
      WBsf220110
      WBsf220111
  Experimental_info: RNAi_result: WBRNAi00076548 Inferred_automatically: RNAi_primary
      WBRNAi00003946 Inferred_automatically: RNAi_primary
      WBRNAi00116834 Inferred_automatically: RNAi_primary
      WBRNAi00050093 Inferred_automatically: RNAi_primary
      WBRNAi00034034 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1018481
      Expr1031223
      Expr1153795
      Expr2012718
      Expr2030954
    Drives_construct: WBCnstr00036477
    Construct_product: WBCnstr00036477
    Microarray_results (23)
    Expression_cluster (138)
    Interaction (75)
  Map_info: Map: I Position: 3.8072 Error: 0.000397
    Positive: Positive_clone: K07A1 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00055090
    WBPaper00064057
    WBPaper00064339
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene