WormBase Tree Display for Gene: WBGene00002070

WBGene00002070 Evidence: Person_evidence: WBPerson842
  SMap: S_parent: Sequence: K07A1
  Identity: Version: 1
    Name: CGC_name: ile-1 Person_evidence: WBPerson842
      Sequence_name: K07A1.8
      Molecular_name: K07A1.8
        K07A1.8.1
        CE11854
      Other_name: CELE_K07A1.8 Accession_evidence: NDB BX284601
      Public_name: ile-1
    DB_info: Database: AceView gene 1K186
        WormQTL gene WBGene00002070
        WormFlux gene WBGene00002070
        NDB locus_tag CELE_K07A1.8
        Panther gene CAEEL|WormBase=WBGene00002070|UniProtKB=G5EDE8
          family PTHR12223
        NCBI gene 172799
        RefSeq protein NM_060147.7
        TREEFAM TREEFAM_ID TF313311
        TrEMBL UniProtAcc G5EDE8
        UniProt_GCRP UniProtAcc G5EDE8
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:26 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: ile
    Allele (33)
    Strain: WBStrain00055467
    RNASeq_FPKM (74)
    GO_annotation: 00013889
      00013890
      00013891
      00013892
      00013893
      00013894
      00013895
      00105739
      00109967
    Ortholog: WBGene00026516 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00161381 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00162423 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00077035 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00134596 Caenorhabditis japonica From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00193453 Caenorhabditis brenneri From_analysis: WormBase-Compara
      WBGene00225110 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g12299 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g6829 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g3643 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g7738 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g13477 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g25315 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP31.g575 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g8050 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g18630 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g10347 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP39.g7686 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g622 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00869.g14650 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-ile-1 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold629.g14681 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00194.g6746 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_11623 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_000547 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g05972 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g631 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_10067700 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrI_pilon.g1856 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00206630 Caenorhabditis japonica From_analysis: WormBase-Compara
      WBGene00216559 Caenorhabditis japonica From_analysis: WormBase-Compara
      WBGene00237052 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00258749 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00287808 Trichuris muris From_analysis: WormBase-Compara
      SGD:S000001846 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            Panther
      SGD:S000004070 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            Panther
      FB:FBgn0035909 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-060201-4 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:6631 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:6632 Homo sapiens From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
            PhylomeDB
      MGI:1917611 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:2667537 Mus musculus From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
            PhylomeDB
      RGD:71020 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1310538 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
            PhylomeDB
    Paralog: WBGene00002071 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Concise_description: ile-1 is orthologous to the human gene human ERGIC-53, which when mutated leads to deficiency of coagulation factors V/VIII (OMIM:227300). Paper_evidence: WBPaper00004103
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable mannose binding activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in factor V deficiency and factor XIII deficiency. Is an ortholog of human LMAN1 (lectin, mannose binding 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:2211 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6631)
      DOID:2216 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6631)
  Molecular_info: Corresponding_CDS: K07A1.8
    Corresponding_transcript: K07A1.8.1
    Other_sequence (64)
    Associated_feature: WBsf649498
      WBsf664767
      WBsf976906
      WBsf976907
      WBsf976908
      WBsf976909
      WBsf984761
      WBsf220109
      WBsf220110
      WBsf220111
  Experimental_info: RNAi_result: WBRNAi00076548 Inferred_automatically: RNAi_primary
      WBRNAi00003946 Inferred_automatically: RNAi_primary
      WBRNAi00116834 Inferred_automatically: RNAi_primary
      WBRNAi00050093 Inferred_automatically: RNAi_primary
      WBRNAi00034034 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1018481
      Expr1031223
      Expr1153795
      Expr2012718
      Expr2030954
    Drives_construct: WBCnstr00036477
    Construct_product: WBCnstr00036477
    Microarray_results (23)
    Expression_cluster (138)
    Interaction (75)
  Map_info: Map: I Position: 3.8072 Error: 0.000397
    Positive: Positive_clone: K07A1 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00055090
    WBPaper00064057
    WBPaper00064339
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene