WormBase Tree Display for Gene: WBGene00002056

WBGene00002056 SMap: S_parent: Sequence: CHROMOSOME_X
  Identity: Version: 4
    Name: CGC_name: ifc-2 Person_evidence: WBPerson105
            WBPerson293
            WBPerson260
      Sequence_name: M6.1
      Molecular_name (19)
      Other_name: Cel IF C2 Accession_evidence: X70832
        CelIF c2
        ecp-1 Paper_evidence: WBPaper00057164
        exc-2 Person_evidence: WBPerson260
          Curator_confirmed: WBPerson51134
          Date_last_updated: 07 Aug 2023 16:20:23
        CELE_M6.1 Accession_evidence: NDB BX284606
      Public_name: ifc-2
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:26 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 09 Mar 2021 13:49:30 WBPerson1983 Name_change: Other_name: ecp-1
        3 07 Aug 2023 16:03:35 WBPerson51134 Event: Acquires_merge: WBGene00001363
        4 13 Oct 2023 01:37:05 WBPerson51134 Name_change: CGC_name: ifc-2
                Other_name: exc-2
      Acquires_merge: WBGene00001363
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: ifc
    Allele: WBVar02153085
      WBVar00241543 Inferred_automatically: From strain object: NJ340
      WBVar02148917
      WBVar00278481
      WBVar00278483
      WBVar02149960
      WBVar00145633
      WBVar00251376
      WBVar02048382
      WBVar01823969
      WBVar01823970
      WBVar01823971
      WBVar01823972
      WBVar01498638
      WBVar01618308
      WBVar00277294
      WBVar00074374
      WBVar00074375
      WBVar00074376
      WBVar00074377
      WBVar01834953
      WBVar01979042
      WBVar01114230
      WBVar01114231
      WBVar01114232
      WBVar01114233
      WBVar01114234
      WBVar01114235
      WBVar01114236
      WBVar00241537
      WBVar01114237
      WBVar01114238
      WBVar01114239
      WBVar01114240
      WBVar01114241
      WBVar01114242
      WBVar01467338
      WBVar01114243
      WBVar01114244
      WBVar01114245
      WBVar01114246
      WBVar01114247
      WBVar01114248
      WBVar02008979
      WBVar01114249
      WBVar01114250
      WBVar01114251
      WBVar01486176
      WBVar01639593
      WBVar01114252
      WBVar01114253
      WBVar01639594
      WBVar02138585
      WBVar01114254
      WBVar01639595
      WBVar01114255
      WBVar01114256
      WBVar01114257
      WBVar00492792
      WBVar01114258
      WBVar00492793
      WBVar01114259
      WBVar01114260
      WBVar00492794
      WBVar00492795
      WBVar01114261
      WBVar01114262
      WBVar00492796
      WBVar01114263
      WBVar00492797
      WBVar01114264
      WBVar00492798
      WBVar01114265
      WBVar00492799
      WBVar00492800
      WBVar01114266
      WBVar00492801
      WBVar01114267
      WBVar02051065
      WBVar01114268
      WBVar00492802
      WBVar01114269
      WBVar01782159
      WBVar00492803
      WBVar00492804
      WBVar01114270
      WBVar01114271
      WBVar00492805
      WBVar00492806
      WBVar01114272
      WBVar00492807
      WBVar01114273
      WBVar00492808
      WBVar01114274
      WBVar00492809
      WBVar01114275
      WBVar00492810
      WBVar01114276
      WBVar01114277
      WBVar00492811
      WBVar00492812
      WBVar01114278
      WBVar01499636
      WBVar00492813
      WBVar01114279
      WBVar00492814
      WBVar01114280
      WBVar01114281
      WBVar00492815
      WBVar01114282
      WBVar00492816
      WBVar00492817
      WBVar01114283
      WBVar00492818
      WBVar01114284
      WBVar01114285
      WBVar00492819
      WBVar01114286
      WBVar00492820
      WBVar01114287
      WBVar00492821
      WBVar01114288
      WBVar01114289
      WBVar01114290
      WBVar01114291
      WBVar01114292
      WBVar01114293
      WBVar01114294
      WBVar01114295
      WBVar01114296
      WBVar01114297
      WBVar01114298
      WBVar01114299
      WBVar01114300
      WBVar01992468
      WBVar01114301
      WBVar01114302
      WBVar01114303
      WBVar01114304
      WBVar01114305
      WBVar01114306
      WBVar01114307
      WBVar01114308
      WBVar01114309
      WBVar01690010
      WBVar01600338
      WBVar01600339
      WBVar01600340
      WBVar00299079
      WBVar01600341
      WBVar01986943
      WBVar01986944
      WBVar01986945
    Legacy_information: [Buechner M] exc for excretory canal defect. Canals are very short and consist of a series of vacuoles. 100% penetrant. Usually visible by low-power microscopy.
      [C.elegansII] rh90 : excretory canal defect. Canals are very short and consist of a series of vacuoles. Luminal coat partly detached, floats in canal.100% penetrant.Usually visible by low-power microscopy. Affects tail spike ??? OA1: rh105. [NJ]
    Strain: WBStrain00002850
      WBStrain00028840
      WBStrain00047374
    RNASeq_FPKM (74)
    GO_annotation (17)
    Ortholog (61)
    Paralog (12)
    Structured_description: Concise_description: ifc-2 encodes three isoforms of an intermediate filament protein dispensable for viability but required for normal movement, growth rate, body size, body shape, and cuticle strength; IFC-2 is present in the cytoplasm of intestinal cells, and at the desmosomes of intestinal and pharyngeal cells. Paper_evidence: WBPaper00001981
            WBPaper00004761
            WBPaper00005492
            WBPaper00006137
          Curator_confirmed: WBPerson1843
            WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to be a structural constituent of cytoskeleton. Involved in post-embryonic digestive tract morphogenesis. Located in cytoplasm and desmosome. Expressed in several structures, including excretory canal; pharyngeal-intestinal valve; pharynx; rectal valve cell; and uterus. Human ortholog(s) of this gene implicated in several diseases, including Dowling-Degos disease; ichthyosis (multiple); and palmoplantar keratosis (multiple). Is an ortholog of several human genes including KRT1 (keratin 1); KRT2 (keratin 2); and KRT3 (keratin 3). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model (14)
  Molecular_info: Corresponding_CDS: M6.1a
      M6.1b
      M6.1c
      M6.1d
      M6.1e
      M6.1f
    Corresponding_CDS_history: M6.1a:wp272
      M6.1b:wp272
      M6.1c:wp272
    Corresponding_transcript: M6.1a.1
      M6.1a.2
      M6.1b.1
      M6.1c.1
      M6.1d.1
      M6.1e.1
      M6.1f.1
    Other_sequence: CR07924
      FD516689.1
      CBC09732_1
      CJC02211_1
      CBC03886_1
      CSC00034_1
      CRC05750_1
    Associated_feature (13)
  Experimental_info: RNAi_result (27)
    Expr_pattern (17)
    Drives_construct: WBCnstr00003372
      WBCnstr00036488
      WBCnstr00042147
      WBCnstr00042148
      WBCnstr00042149
    Construct_product: WBCnstr00036488
      WBCnstr00042019
      WBCnstr00042020
      WBCnstr00042147
    Antibody: WBAntibody00000563
      WBAntibody00002893
      WBAntibody00002913
    Microarray_results (39)
    Expression_cluster (285)
    Interaction (77)
  Map_info: Map: X Position: -19.5186 Error: 0.005743
    Positive: Positive_clone: M6 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4971
    Pseudo_map_position
  Reference (41)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene