WormBase Tree Display for Gene: WBGene00002051
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| WBGene00002051 | SMap | S_parent | Sequence | CHROMOSOME_X | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | ifa-3 | Person_evidence | WBPerson105 | |||||
| WBPerson293 | |||||||||
| Sequence_name | F52E10.5 | ||||||||
| Molecular_name | F52E10.5 | ||||||||
| F52E10.5.1 | |||||||||
| CE34875 | |||||||||
| Other_name | Cel IF A3 | Accession_evidence | EMBL | X70831 | |||||
| CelIF a3 | |||||||||
| A3 | Paper_evidence | WBPaper00006137 | |||||||
| CELE_F52E10.5 | Accession_evidence | NDB | BX284606 | ||||||
| Public_name | ifa-3 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ifa | ||||||||
| Allele (42) | |||||||||
| Strain | WBStrain00036840 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (12) | |||||||||
| Ortholog (69) | |||||||||
| Paralog (12) | |||||||||
| Structured_description | Concise_description | ifa-3 encodes an essential intermediate filament protein that is coexpressed with the essential IF protein IFB-1; IFA-3 is required for survival past early larval stages, correct positioning of excretory canals and body muscles, attachment of cuticle to hypodermis, and locomotion; IFA-3 forms heteropolymeric intermediate filaments in vitro with an equimolar mixture of IFB-1; IFA-3 is expressed in embryonic and larval, but not adult, hypodermis. | Paper_evidence | WBPaper00001981 | |||||
| WBPaper00004761 | |||||||||
| WBPaper00006137 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in cellular localization; heterochromatin formation; and nucleus organization. Predicted to be located in nuclear envelope and nuclear lamina. Expressed in hypodermis and ventral cord neurons. Human ortholog(s) of this gene implicated in partial lipodystrophy; primary autosomal recessive microcephaly; and progressive myoclonus epilepsy 9. Is an ortholog of human LMNB2 (lamin B2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0111450 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6638) | ||||
| DOID:0070296 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6638) | ||||||
| DOID:0080299 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6638) | ||||||
| Molecular_info | Corresponding_CDS | F52E10.5 | |||||||
| Corresponding_CDS_history | F52E10.5:wp83 | ||||||||
| F52E10.5:wp102 | |||||||||
| F52E10.5:wp106 | |||||||||
| Corresponding_transcript | F52E10.5.1 | ||||||||
| Other_sequence (33) | |||||||||
| Associated_feature | WBsf718810 | ||||||||
| WBsf238387 | |||||||||
| WBsf238388 | |||||||||
| Experimental_info | RNAi_result (16) | ||||||||
| Expr_pattern | Expr1496 | ||||||||
| Expr1020134 | |||||||||
| Expr1031204 | |||||||||
| Expr1151810 | |||||||||
| Expr2012677 | |||||||||
| Expr2030913 | |||||||||
| Drives_construct | WBCnstr00008111 | ||||||||
| WBCnstr00036493 | |||||||||
| Construct_product | WBCnstr00008111 | ||||||||
| WBCnstr00036493 | |||||||||
| Microarray_results (16) | |||||||||
| Expression_cluster (161) | |||||||||
| Interaction (71) | |||||||||
| Map_info | Map | X | Position | 23.7263 | Error | 0.00238 | |||
| Positive | Positive_clone | F52E10 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (15) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
