WormBase Tree Display for Gene: WBGene00002050
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WBGene00002050 | SMap | S_parent | Sequence | CHROMOSOME_X | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | ifa-1 | Person_evidence | WBPerson105 | |||||
WBPerson293 | |||||||||
Sequence_name | F38B2.1 | ||||||||
Molecular_name (15) | |||||||||
Other_name | Cel IF A1 | Accession_evidence | EMBL | X70834 | |||||
CelIF a1 | |||||||||
A1 | Paper_evidence | WBPaper00006137 | |||||||
CELE_F38B2.1 | Accession_evidence | NDB | BX284606 | ||||||
Public_name | ifa-1 | ||||||||
DB_info | Database (12) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | ifa | ||||||||
Allele (77) | |||||||||
Strain | WBStrain00036052 | ||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (14) | |||||||||
Ortholog (65) | |||||||||
Paralog (12) | |||||||||
Structured_description | Concise_description | IFA-1 encodes an essential intermediate filament protein that is coexpressed with the essential IF protein IFB-1; IFA-1 is required for survival past the L1 larva stage, and a normal intestine; IFA-1 forms heteropolymeric intermediate filaments in vitro with an equimolar mixture of IFB-1; IFA-1 is predicted to function as a structural component of the cytoskeleton, and is required for larval development and normal intestinal morphology; ifa-1 is expressed in amphid sensory neurons, in tail neurons and other unidentified neurons, some pharyngeal muscles, the pharyngeal-intestinal valve, the vulva, and the rectum. | Paper_evidence | WBPaper00001981 | |||||
WBPaper00004761 | |||||||||
WBPaper00006137 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
Automated_description | Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in cellular localization; heterochromatin formation; and nucleus organization. Located in intermediate filament. Expressed in several structures, including egg-laying apparatus; excretory cell; neurons; pharyngeal-intestinal valve; and pharynx. Human ortholog(s) of this gene implicated in partial lipodystrophy; primary autosomal recessive microcephaly; and progressive myoclonus epilepsy 9. Is an ortholog of human LMNB2 (lamin B2). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:0111450 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6638) | ||||
DOID:0070296 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6638) | ||||||
DOID:0080299 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6638) | ||||||
Molecular_info | Corresponding_CDS (5) | ||||||||
Corresponding_CDS_history | F38B2.1:wp83 | ||||||||
Corresponding_transcript (5) | |||||||||
Other_sequence (241) | |||||||||
Associated_feature (14) | |||||||||
Experimental_info | RNAi_result (48) | ||||||||
Expr_pattern | Expr1495 | ||||||||
Expr2762 | |||||||||
Expr1013956 | |||||||||
Expr1031203 | |||||||||
Expr1150559 | |||||||||
Expr2012676 | |||||||||
Expr2030912 | |||||||||
Drives_construct | WBCnstr00010937 | ||||||||
WBCnstr00036494 | |||||||||
Construct_product | WBCnstr00010937 | ||||||||
WBCnstr00036494 | |||||||||
Microarray_results (39) | |||||||||
Expression_cluster (212) | |||||||||
Interaction (72) | |||||||||
Map_info | Map | X | Position | 2.86537 | Error | 0.001386 | |||
Positive | Positive_clone | F38B2 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Mapping_data | Multi_point | 4945 | |||||||
4421 | |||||||||
4442 | |||||||||
Pseudo_map_position | |||||||||
Reference (14) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |