WormBase Tree Display for Gene: WBGene00002050
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| WBGene00002050 | SMap | S_parent | Sequence | CHROMOSOME_X | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | ifa-1 | Person_evidence | WBPerson105 | |||||
| WBPerson293 | |||||||||
| Sequence_name | F38B2.1 | ||||||||
| Molecular_name | F38B2.1a | ||||||||
| F38B2.1a.1 | |||||||||
| CE31506 | |||||||||
| F38B2.1b | |||||||||
| CE31507 | |||||||||
| F38B2.1c | |||||||||
| CE05824 | |||||||||
| F38B2.1d | |||||||||
| CE24961 | |||||||||
| F38B2.1e | |||||||||
| CE53169 | |||||||||
| F38B2.1b.1 | |||||||||
| F38B2.1c.1 | |||||||||
| F38B2.1d.1 | |||||||||
| F38B2.1e.1 | |||||||||
| Other_name | Cel IF A1 | Accession_evidence | EMBL | X70834 | |||||
| CelIF a1 | |||||||||
| A1 | Paper_evidence | WBPaper00006137 | |||||||
| CELE_F38B2.1 | Accession_evidence | NDB | BX284606 | ||||||
| Public_name | ifa-1 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ifa | ||||||||
| Allele (77) | |||||||||
| Strain | WBStrain00036052 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (14) | |||||||||
| Ortholog (65) | |||||||||
| Paralog (12) | |||||||||
| Structured_description | Concise_description | IFA-1 encodes an essential intermediate filament protein that is coexpressed with the essential IF protein IFB-1; IFA-1 is required for survival past the L1 larva stage, and a normal intestine; IFA-1 forms heteropolymeric intermediate filaments in vitro with an equimolar mixture of IFB-1; IFA-1 is predicted to function as a structural component of the cytoskeleton, and is required for larval development and normal intestinal morphology; ifa-1 is expressed in amphid sensory neurons, in tail neurons and other unidentified neurons, some pharyngeal muscles, the pharyngeal-intestinal valve, the vulva, and the rectum. | Paper_evidence | WBPaper00001981 | |||||
| WBPaper00004761 | |||||||||
| WBPaper00006137 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in cellular localization; heterochromatin formation; and nucleus organization. Located in intermediate filament. Expressed in several structures, including egg-laying apparatus; excretory cell; neurons; pharyngeal-intestinal valve; and pharynx. Human ortholog(s) of this gene implicated in partial lipodystrophy; primary autosomal recessive microcephaly; and progressive myoclonus epilepsy 9. Is an ortholog of human LMNB2 (lamin B2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0111450 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6638) | ||||
| DOID:0070296 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6638) | ||||||
| DOID:0080299 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6638) | ||||||
| Molecular_info | Corresponding_CDS | F38B2.1a | |||||||
| F38B2.1b | |||||||||
| F38B2.1c | |||||||||
| F38B2.1d | |||||||||
| F38B2.1e | |||||||||
| Corresponding_CDS_history | F38B2.1:wp83 | ||||||||
| Corresponding_transcript | F38B2.1a.1 | ||||||||
| F38B2.1b.1 | |||||||||
| F38B2.1c.1 | |||||||||
| F38B2.1d.1 | |||||||||
| F38B2.1e.1 | |||||||||
| Other_sequence (241) | |||||||||
| Associated_feature (14) | |||||||||
| Experimental_info | RNAi_result (48) | ||||||||
| Expr_pattern | Expr1495 | ||||||||
| Expr2762 | |||||||||
| Expr1013956 | |||||||||
| Expr1031203 | |||||||||
| Expr1150559 | |||||||||
| Expr2012676 | |||||||||
| Expr2030912 | |||||||||
| Drives_construct | WBCnstr00010937 | ||||||||
| WBCnstr00036494 | |||||||||
| Construct_product | WBCnstr00010937 | ||||||||
| WBCnstr00036494 | |||||||||
| Microarray_results (39) | |||||||||
| Expression_cluster (212) | |||||||||
| Interaction | WBInteraction000029165 | ||||||||
| WBInteraction000029769 | |||||||||
| WBInteraction000029777 | |||||||||
| WBInteraction000040908 | |||||||||
| WBInteraction000044847 | |||||||||
| WBInteraction000045233 | |||||||||
| WBInteraction000045534 | |||||||||
| WBInteraction000166840 | |||||||||
| WBInteraction000217940 | |||||||||
| WBInteraction000217941 | |||||||||
| WBInteraction000217942 | |||||||||
| WBInteraction000252137 | |||||||||
| WBInteraction000321662 | |||||||||
| WBInteraction000329052 | |||||||||
| WBInteraction000336891 | |||||||||
| WBInteraction000341912 | |||||||||
| WBInteraction000363732 | |||||||||
| WBInteraction000376785 | |||||||||
| WBInteraction000384172 | |||||||||
| WBInteraction000390888 | |||||||||
| WBInteraction000407470 | |||||||||
| WBInteraction000416207 | |||||||||
| WBInteraction000426075 | |||||||||
| WBInteraction000444153 | |||||||||
| WBInteraction000455290 | |||||||||
| WBInteraction000510188 | |||||||||
| WBInteraction000510814 | |||||||||
| WBInteraction000515079 | |||||||||
| WBInteraction000515109 | |||||||||
| WBInteraction000516758 | |||||||||
| WBInteraction000516791 | |||||||||
| WBInteraction000516962 | |||||||||
| WBInteraction000516982 | |||||||||
| WBInteraction000540542 | |||||||||
| WBInteraction000543134 | |||||||||
| WBInteraction000543675 | |||||||||
| WBInteraction000543931 | |||||||||
| WBInteraction000546171 | |||||||||
| WBInteraction000550721 | |||||||||
| WBInteraction000550734 | |||||||||
| WBInteraction000550801 | |||||||||
| WBInteraction000551452 | |||||||||
| WBInteraction000552794 | |||||||||
| WBInteraction000553874 | |||||||||
| WBInteraction000561736 | |||||||||
| WBInteraction000562238 | |||||||||
| WBInteraction000562357 | |||||||||
| WBInteraction000563381 | |||||||||
| WBInteraction000563386 | |||||||||
| WBInteraction000563387 | |||||||||
| WBInteraction000563388 | |||||||||
| WBInteraction000563389 | |||||||||
| WBInteraction000563390 | |||||||||
| WBInteraction000563391 | |||||||||
| WBInteraction000563392 | |||||||||
| WBInteraction000563393 | |||||||||
| WBInteraction000563394 | |||||||||
| WBInteraction000563395 | |||||||||
| WBInteraction000563955 | |||||||||
| WBInteraction000564582 | |||||||||
| WBInteraction000565342 | |||||||||
| WBInteraction000566231 | |||||||||
| WBInteraction000566510 | |||||||||
| WBInteraction000566777 | |||||||||
| WBInteraction000571715 | |||||||||
| WBInteraction000572520 | |||||||||
| WBInteraction000572758 | |||||||||
| WBInteraction000578781 | |||||||||
| WBInteraction000583012 | |||||||||
| WBInteraction000583741 | |||||||||
| WBInteraction000584100 | |||||||||
| WBInteraction000586592 | |||||||||
| Map_info | Map | X | Position | 2.86537 | Error | 0.001386 | |||
| Positive | Positive_clone | F38B2 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4945 | |||||||
| 4421 | |||||||||
| 4442 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (14) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
