Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Gene: WBGene00002050

expand all nodes | collapse all nodes | view schema

Name Class

WBGene00002050SMapS_parentSequenceCHROMOSOME_X
IdentityVersion1
NameCGC_nameifa-1Person_evidenceWBPerson105
WBPerson293
Sequence_nameF38B2.1
Molecular_name (15)
Other_nameCel IF A1Accession_evidenceEMBLX70834
CelIF a1
A1Paper_evidenceWBPaper00006137
CELE_F38B2.1Accession_evidenceNDBBX284606
Public_nameifa-1
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:26WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classifa
Allele (77)
StrainWBStrain00036052
RNASeq_FPKM (74)
GO_annotation00003708
00003709
00049423
00049424
00049425
00049426
00049427
00049428
00049429
00049430
00049431
00049432
00049433
00049434
Ortholog (65)
Paralog (12)
Structured_descriptionConcise_descriptionIFA-1 encodes an essential intermediate filament protein that is coexpressed with the essential IF protein IFB-1; IFA-1 is required for survival past the L1 larva stage, and a normal intestine; IFA-1 forms heteropolymeric intermediate filaments in vitro with an equimolar mixture of IFB-1; IFA-1 is predicted to function as a structural component of the cytoskeleton, and is required for larval development and normal intestinal morphology; ifa-1 is expressed in amphid sensory neurons, in tail neurons and other unidentified neurons, some pharyngeal muscles, the pharyngeal-intestinal valve, the vulva, and the rectum.Paper_evidenceWBPaper00001981
WBPaper00004761
WBPaper00006137
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to be a structural constituent of cytoskeleton. Predicted to be involved in cellular localization; heterochromatin formation; and nucleus organization. Located in intermediate filament. Expressed in several structures, including egg-laying apparatus; excretory cell; neurons; pharyngeal-intestinal valve; and pharynx. Human ortholog(s) of this gene implicated in partial lipodystrophy; primary autosomal recessive microcephaly; and progressive myoclonus epilepsy 9. Is an ortholog of human LMNB2 (lamin B2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0111450Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6638)
DOID:0070296Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6638)
DOID:0080299Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6638)
Molecular_infoCorresponding_CDSF38B2.1a
F38B2.1b
F38B2.1c
F38B2.1d
F38B2.1e
Corresponding_CDS_historyF38B2.1:wp83
Corresponding_transcriptF38B2.1a.1
F38B2.1b.1
F38B2.1c.1
F38B2.1d.1
F38B2.1e.1
Other_sequenceHGC10904_1
AS02094
GR13420
ACC38236_1
AS13264
ACC18044_1
BF199444.1
JI170108.1
ES744665.1
FG619799.1
NBC02227_1
TDC02295_1
EX552993.1
EX501789.1
EW741518.1
BF199481.1
HG04134
JI477999.1
EY459048.1
TSC01166_1
FC542655.1
BUC01608_1
MIC00771_1
FC809782.1
Dviv_isotig09406
Tcol_isotig17280
ES564062.1
JO468053.1
MI04312
ES560553.1
AA901457.1
EX537287.1
EY458859.1
EY468815.1
HC00380
L31528.1
FC815711.1
MHC00695_1
EX558614.1
FK806690.1
ASC00083_1
EX544700.1
TSC02644_1
FC549150.1
Dviv_isotig09404
AW980259.1
MC03110
FC541246.1
FC815830.1
Tcol_isotig16103
FC545438.1
FF679843.1
Dviv_isotig09407
DI01806
L05918.1
ES566861.1
SR00472
AI077021.1
FC549309.1
EX547762.1
AI444854.1
Tcol_isotig03325
SS03039
ACC33908_1
FC548455.1
TMC00903_1
FC810424.1
ACC37373_1
FC543537.1
Acan_isotig19277
EX913138.1
JI463561.1
Tcol_isotig22963
AY154743.1
AS15940
EX547224.1
XIC03302_1
TVC00905_1
ES566869.1
ES410004.1
FG586032.1
ES565401.1
JI478685.1
FG974424.1
FG350827.1
TS03324
TM00759
FC554719.1
EX915577.1
FK801404.1
ES411938.1
EY464644.1
Acan_isotig07963
AS04187
EX543277.1
ES566067.1
CR08587
FE905597.1
MC00304
BMC04239_1
ACC10658_1
MJ03034
EX544903.1
Tcol_isotig03326
EW742658.1
MHC01452_1
OVC00810_1
Dviv_isotig09405
FC548301.1
EY472255.1
JI178827.1
EX547260.1
SRC00569_1
SR01832
EY458365.1
FK808737.1
Tcol_isotig03324
M95554.1
EX557139.1
FC548780.1
HBC10473_1
FG350352.1
EY468486.1
FG585767.1
EX561657.1
Dviv_isotig09402
FK808706.1
HG09315
FG586785.1
EX008556.1
HBC28321_1
EX560716.1
ASC06658_1
JI182189.1
BF199432.1
X68557.1
GO252174.1
MJC02043_1
FF679527.1
MHC00544_1
OVC01728_1
CRC11150_1
AI815264.1
AYC02365_1
ACC20929_1
AS02442
BU586281.1
Acan_isotig17453
JI472553.1
BMC05333_1
FC546348.1
ACC08746_1
TMC00671_1
GP03374
Hbac_isotig01117
JI219185.1
AE03590
EX566430.1
GP01179
EY458766.1
AI670483.1
EX564581.1
FC554643.1
BE636422.1
EX547475.1
MH07820
MI02698
CRC11623_1
BM174335.1
ACC10231_1
FC544162.1
BM277502.1
EX559612.1
MH00413
TS00612
SS03045
PPC05466_1
FC547715.1
X68558.1
MI01001
AF237484.1
JI464182.1
EX543228.1
CJC05051_1
FG350074.1
FE908279.1
FC546280.1
L23872.1
AYC03679_1
X86089.1
AA917260.1
AI665775.1
GPC02728_1
SRC02131_1
DIC01027_1
JI165647.1
FC547131.1
EY459518.1
MCC01169_1
ASC13182_1
FK807306.1
HCC00374_1
BMC00640_1
ES273159.1
MI02699
FK801401.1
Tcir_isotig20838
AS02280
XI02635
Hbac_isotig00255
EX501370.1
BF824665.1
Tcir_isotig09331
EX009715.1
ES561904.1
JO475139.1
JI168653.1
AI444905.1
BG734386.1
ACC10353_1
JI473865.1
AE00177
EX552712.1
GRC01567_1
Tcol_isotig15186
Oden_isotig19073
SSC02210_1
S77073.1
ES566095.1
AI317899.1
MH01980
FG580130.1
TSC00225_1
HBC07194_1
TM01295
ES410754.1
GPC00629_1
JI173978.1
FE908860.1
Dviv_isotig09403
EX015282.1
Associated_feature (14)
Experimental_infoRNAi_result (48)
Expr_patternExpr1495
Expr2762
Expr1013956
Expr1031203
Expr1150559
Expr2012676
Expr2030912
Drives_constructWBCnstr00010937
WBCnstr00036494
Construct_productWBCnstr00010937
WBCnstr00036494
Microarray_results (39)
Expression_cluster (212)
Interaction (72)
Map_infoMapXPosition2.86537Error0.001386
PositivePositive_cloneF38B2Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4945
4421
4442
Pseudo_map_position
Reference (14)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene