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WormBase Tree Display for Gene: WBGene00001945

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Name Class

WBGene00001945SMapS_parentSequenceF45E1
IdentityVersion1
NameCGC_namehis-71Person_evidenceWBPerson160
Sequence_nameF45E1.6
Molecular_nameF45E1.6
F45E1.6.1
CE01943
Other_nameCELE_F45E1.6Accession_evidenceNDBBX284606
Public_namehis-71
DB_infoDatabaseAceViewgeneXI600
WormQTLgeneWBGene00001945
WormFluxgeneWBGene00001945
NDBlocus_tagCELE_F45E1.6
PanthergeneCAEEL|WormBase=WBGene00001945|UniProtKB=Q10453
familyPTHR11426
NCBIgene181057
RefSeqproteinNM_076943.7
SwissProtUniProtAccQ10453
UniProt_GCRPUniProtAccQ10453
OMIMgene601058
601128
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:26WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classhis
Allele (20)
Possibly_affected_byWBVar02153220
StrainWBStrain00032472
WBStrain00007466
WBStrain00007461
WBStrain00034735
RNASeq_FPKM (74)
GO_annotation (11)
Ortholog (59)
Paralog (24)
Structured_descriptionConcise_descriptionhis-71 encodes an H3 histone required for embryonic viability, body morphology, and larval viability.Paper_evidenceWBPaper00004651
WBPaper00005654
Curator_confirmedWBPerson48
WBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be located in nucleus. Predicted to be part of nucleosome. Expressed in several structures, including somatic cell. Is an ortholog of human H3-3A (H3.3 histone A) and H3-3B (H3.3 histone B).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelEFO:MONDO:0031200Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4764,HGNC:4765)
Molecular_infoCorresponding_CDSF45E1.6
Corresponding_transcriptF45E1.6.1
Other_sequence (183)
Associated_featureWBsf1006004
WBsf1006005
WBsf1006006
WBsf1023340
WBsf237632
Experimental_infoRNAi_result (21)
Expr_patternExpr4220
Expr4296
Expr6076
Expr15136
Expr1015060
Expr1151237
Expr1200188
Expr2012481
Expr2030720
Drives_constructWBCnstr00002895
WBCnstr00011836
WBCnstr00011893
WBCnstr00016936
WBCnstr00036571
Construct_productWBCnstr00011836
WBCnstr00016936
WBCnstr00036571
Regulate_expr_clusterWBPaper00054191:H3.3(null)_embryo_downregulated
WBPaper00054191:H3.3(null)_embryo_upregulated
WBPaper00054191:H3.3(null)_L1_downregulated
WBPaper00054191:H3.3(null)_L1_upregulated
Microarray_results (16)
Expression_cluster (198)
Interaction (212)
Map_infoMapXPosition-0.766026Error0.018254
PositivePositive_cloneF45E1Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point5256
Pseudo_map_position
Reference (12)
RemarkSequence connection corrected from F54E1.6 [krb 030423]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene