WormBase Tree Display for Gene: WBGene00001831
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| WBGene00001831 | SMap | S_parent | Sequence | F58A4 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | hcp-3 | Person_evidence | WBPerson537 | |||||
| Sequence_name | F58A4.3 | ||||||||
| Molecular_name | F58A4.3 | ||||||||
| F58A4.3.1 | |||||||||
| CE00219 | |||||||||
| Other_name | CeCENP-A | Paper_evidence | WBPaper00026659 | ||||||
| CENP-A | Paper_evidence | WBPaper00053817 | |||||||
| CELE_F58A4.3 | Accession_evidence | NDB | BX284603 | ||||||
| Public_name | hcp-3 | ||||||||
| DB_info | Database | AceView | gene | 3K704 | |||||
| WormQTL | gene | WBGene00001831 | |||||||
| WormFlux | gene | WBGene00001831 | |||||||
| NDB | locus_tag | CELE_F58A4.3 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00001831|UniProtKB=P34470 | |||||||
| family | PTHR11426 | ||||||||
| NCBI | gene | 176359 | |||||||
| RefSeq | protein | NM_066727.7 | |||||||
| SwissProt | UniProtAcc | P34470 | |||||||
| TREEFAM | TREEFAM_ID | TF352440 | |||||||
| UniProt_GCRP | UniProtAcc | P34470 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:25 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | hcp | ||||||||
| Allele (12) | |||||||||
| Strain | WBStrain00036564 | ||||||||
| WBStrain00034729 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (35) | |||||||||
| Ortholog (36) | |||||||||
| Paralog (24) | |||||||||
| Structured_description | Concise_description | The hcp-3 gene encodes a centromere protein (CENP)-A homolog required for kinetochore function; inactivation of hcp-3 in one-cell embryos by RNAi causes a complete loss of kinetochores, with total failure of chromosomes to segregate properly during mitosis, to recruit components to the kinetochore other than HCP-3, or to assemble a stable mitotic spindle; in addition, HCP-4 fails to localize properly to the kinetochore in hcp-3(RNAi) embryos. | Paper_evidence | WBPaper00003702 | |||||
| WBPaper00004736 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 16 Dec 2005 00:00:00 | ||||||||
| Automated_description | Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Involved in several processes, including negative regulation of mitotic centrosome separation; non-membrane-bounded organelle assembly; and protein localization to chromosome. Located in kinetochore and nucleus. Expressed in embryonic cell; hyp3; hyp4; hyp7 syncytium; and seam cell. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F58A4.3 | |||||||
| Corresponding_transcript | F58A4.3.1 | ||||||||
| Other_sequence | CBC08194 | ||||||||
| Associated_feature | WBsf651390 | ||||||||
| WBsf993732 | |||||||||
| WBsf227335 | |||||||||
| Experimental_info | RNAi_result (32) | ||||||||
| Expr_pattern (11) | |||||||||
| Drives_construct | WBCnstr00014536 | ||||||||
| WBCnstr00022767 | |||||||||
| WBCnstr00022768 | |||||||||
| WBCnstr00036660 | |||||||||
| Construct_product | WBCnstr00014534 | ||||||||
| WBCnstr00014535 | |||||||||
| WBCnstr00014536 | |||||||||
| WBCnstr00022767 | |||||||||
| WBCnstr00036660 | |||||||||
| Antibody | WBAntibody00000241 | ||||||||
| WBAntibody00000379 | |||||||||
| WBAntibody00000811 | |||||||||
| WBAntibody00000812 | |||||||||
| WBAntibody00001030 | |||||||||
| WBAntibody00002323 | |||||||||
| WBAntibody00002956 | |||||||||
| Microarray_results (17) | |||||||||
| Expression_cluster (172) | |||||||||
| Interaction (233) | |||||||||
| Map_info | Map | III | Position | 0.752765 | Error | 0.006625 | |||
| Positive | Positive_clone | F58A4 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference (42) | |||||||||
| Remark | Sequence connection from [Moore LL, Roth MB]. krb 13/11/01 | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
