WormBase Tree Display for Gene: WBGene00001753

WBGene00001753 Evidence: Person_evidence: WBPerson1846
  SMap: S_parent: Sequence: R03D7
  Identity: Version: 1
    Name: CGC_name: gst-5
      Sequence_name: R03D7.6
      Molecular_name: R03D7.6a
        R03D7.6a.1
        CE01613
        R03D7.6c
        CE46291
        R03D7.6c.1
      Other_name: CELE_R03D7.6 Accession_evidence: NDB BX284602
      Public_name: gst-5
    DB_info: Database (13)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:25 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: gst
    Allele (30)
    Strain: WBStrain00032747
    RNASeq_FPKM (74)
    GO_annotation: 00008982
      00054968
      00054969
      00054970
      00054971
    Ortholog (31)
    Paralog (45)
    Structured_description: Concise_description: gst-5 encodes a glutathione-S-transferase that inhibits CEP-1- and HUS-1-dependent germline apoptosis, as do BMK-1, RAD-50, and RAD-51. Paper_evidence: WBPaper00023909
          Curator_confirmed: WBPerson567
          Date_last_updated: 21 Apr 2007 00:00:00
      Automated_description: Predicted to enable glutathione transferase activity. Involved in innate immune response. Expressed in intestine and nerve ring. Is an ortholog of human HPGDS (hematopoietic prostaglandin D synthase). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: R03D7.6a
      R03D7.6c
    Corresponding_CDS_history: R03D7.6b:wp279
    Corresponding_transcript: R03D7.6a.1
      R03D7.6c.1
    Other_sequence (308)
    Associated_feature: WBsf019123
      WBsf019124
      WBsf019125
      WBsf019126
      WBsf644636
      WBsf222086
      WBsf222087
  Experimental_info: RNAi_result (11)
    Expr_pattern: Expr11598
      Expr1011457
      Expr1031044
      Expr1154882
      Expr2012329
      Expr2030566
    Drives_construct: WBCnstr00019079
      WBCnstr00036716
    Construct_product: WBCnstr00019079
      WBCnstr00036716
    Regulate_expr_cluster: WBPaper00024245:gst-5-binding_control
      WBPaper00024245:gst-5-binding_ROS-stressed
    Antibody: WBAntibody00001860
    Microarray_results (21)
    Expression_cluster: WBPaper00005013:glutathione-binding_protein
      WBPaper00024505:pharyngeal_enriched
      WBPaper00032121:1uM-Heme_upregulated
      WBPaper00037682:sma-2_downregulated
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:dopaminergic-neurons_larva_enriched
      WBPaper00037950:dopaminergic-neurons_larva_SelectivelyEnriched
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:excretory-cell_larva_enriched
      WBPaper00037950:excretory-cell_larva_SelectivelyEnriched
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_larva_SelectivelyEnriched
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:intestine_larva_enriched
      WBPaper00037950:intestine_larva_SelectivelyEnriched
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038168:lin-15B(n744)_upregulated
      WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00041072:UTX-1_interacting_protein
      WBPaper00041075:hcf-1(-)_skn-1(+)_upregulated
      WBPaper00041954:ethanol_upregulated
      WBPaper00042194:Tryptophan_upregulated
      WBPaper00042215:wdr-23(tm1817)_upregulated
      WBPaper00042561:smgl-1(RNAi)_upregulated
      WBPaper00043945:MeHg_upregulated
      WBPaper00043951:insoluble_protein_day16_N2
      WBPaper00044260:1-methylnicotinamide_upregulated
      WBPaper00044316:CH3HgCl_2.0uM_upregulated
      WBPaper00044316:CH3HgCl_7.5uM_upregulated
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044743:wdr-23_neuron_upregulated
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00045521:Spermatogenic
      WBPaper00045571:germline-ablation_upregulated
      WBPaper00045918:120h_infection_recovery_upregulated
      WBPaper00045974:NSM_enriched_DSN-treated_RNAseq
      WBPaper00045974:NSM_enriched_totalRNA_RNAseq
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00046509:htz-1(ok3099)_upregulated
      WBPaper00047131:daf-2(e1370)_upregulated_N2-background
      WBPaper00048910:Apoptosis-induced_mRNA-interacting_protein
      WBPaper00048910:mRNA-interacting_protein
      WBPaper00048926:miaserin_upregulated_adult-day3
      WBPaper00048952:glucose_repressed
      WBPaper00048988:neuron_expressed
      WBPaper00049266:NaAsO2-Stress_regulated_N2
      WBPaper00049266:NaAsO2-Stress_regulated_trx-1(ok1449)
      WBPaper00049489:AMsh-glia_enriched
      WBPaper00049498:npr-1(ur89)_regulated_7
      WBPaper00049545:cco-1(RNAi)_downregulated
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
      WBPaper00049942:HeatShock_downregulated_hsf-1(RNAi)
      WBPaper00049942:hsf-1(RNAi)_downregulated
      WBPaper00050096:P.aeruginosa_upregulated
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_downregulated_24-cell-embryo
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_downregulated_100-cell-embryo
      WBPaper00050163:chd-3(eh4)_downregulated_24-cell-embryo
      WBPaper00050163:chd-3(eh4)_downregulated_100-cell-embryo
      WBPaper00050332:juglone_upregulated
      WBPaper00050332:skn-1(RNAi)_downregulated
      WBPaper00050412:cco-1(RNAi)_downregulated_N2
      WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
      WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050561:indole_0.1mM-indole_upregulated
      WBPaper00050561:indole_10-fold_upregulated
      WBPaper00050698:DEP-1_interacting
      WBPaper00050801:DAF-12_dauer_regulome
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050801:DPY-21_dauer_regulome
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050903:mir-35-41(nDf50)_25C_upregulated
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00051021:4-bromodiphenyl-ether_upregulated
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:epidermis_nucleus_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:intestine_nucleus_expressed
      WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed
      WBPaper00051404:alg-1(gk214)_downregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053295:lin-22(icb38)_upregulated
      WBPaper00053302:alovudine_24h_regulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053388:dauer_regulated_Cluster3
      WBPaper00053599:female_vs_male_downregulated
      WBPaper00053713:Pheromone-induced_postdauer_vs_control_downregulated
      WBPaper00053713:Starvation-induced_postdauer_vs_control_upregulated
      WBPaper00053771:down_by_skn-1(RNAi)_at_24h-NaCl
      WBPaper00053771:down_by_skn-1(RNAi)_at_dpy-7(e88)
      WBPaper00053771:up_at_3h-NaCl
      WBPaper00053810:daf-2(e1370)_upregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00053814:25C_upregulated_PY79
      WBPaper00054191:H3.3(null)_L1_downregulated
      WBPaper00055049:S.gordonii_upregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin-Psora-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Psora_upregulated
      WBPaper00055354:Rapamycin-Rifampicin-Psora_upregulated
      WBPaper00055354:Rifampicin-Psora_upregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055386:eat-2(ad465)_upregulated
      WBPaper00055626:pry-1(mu38)_downregulated
      WBPaper00055804:FBF-1-FBF-2-associated_spermatogenic-enriched
      WBPaper00055941:nuo-6(qm200);atfs-1(gk3094)_upregulated
      WBPaper00055941:nuo-6(qm200)_upregulated
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056039:efa-6(tm3124)_upregulated
      WBPaper00056073:NHR-86_interacting_promoter
      WBPaper00056275:P.aeruginosa_upregulated
      WBPaper00056275:P.aeruginosa_upregulated_pmk-1(km25)_dependent
      WBPaper00056284:ints-6(t1903)_upregulated
      WBPaper00056284:ints-11(RNAi)_upregulated
      WBPaper00056290:mdt-15(mg584)_upregulated
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00056550:ceh-60(ok1485)_upregulated_AdultDay1
      WBPaper00056826:hmc_biased
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057006:DietaryRestriction_downregulated
      WBPaper00057041:unc-70(cas983)_downregulated
      WBPaper00057068:Cadmium_upregulated
      WBPaper00057154:HeatShock_upregulated_mRNA
      WBPaper00058598:sin-3(tm1276)_upregulated
      WBPaper00058599:benzimidazoles_upregulated
      WBPaper00058711:skn-1(lax188)_upregulated
      WBPaper00058725:sftb-1(cer6)_upregulated
      WBPaper00058948:PA14_downregulated
      WBPaper00059027:neuron-synapses_depleted
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00059471:EGL-43_interacting
      WBPaper00059566:wdr-23(mac32)_upregulated
      WBPaper00059604:fluvastatin_downregulated_dlk-1(km12)
      WBPaper00059604:fluvastatin_downregulated_N2
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059728:5ug_cholesterol_upregulated
      WBPaper00059728:20ug_cholesterol_upregulated
      WBPaper00059754:C.neoformans_H99_upregulated
      WBPaper00059754:E.faecalis_OG1RF_upregulated
      WBPaper00059754:P.aeruginosa_PA14_upregulated
      WBPaper00059895:wounding_upregulated
      WBPaper00059987:Wounding_upregulated
      WBPaper00060084:cco-1(RNAi)_downregulated_N2
      WBPaper00060358:B.thuringiensis_non-pathogen_regulated_elt-2(RNAi)
      WBPaper00060399:CoCl2_6hr_upregulated_N2
      WBPaper00060399:pqm-1(ok485)_upregulated_CoCl2_6hr
      WBPaper00060434:pH4.33_vs_pH6.33_uprgulated
      WBPaper00060459:bcat-1(RNAi)_upregulated
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060683:hlh-11(overexpression)_upregulated
      WBPaper00060811:L1_vs_adult_upregulated_neural
      WBPaper00061007:HB115_upregulated
      WBPaper00061081:E.faecalis_upregulated_N2
      WBPaper00061081:E.faecalis_upregulated_skpo-1(ok1640)
      WBPaper00061203:sin-3(tm1276)_downregulated
      WBPaper00061274:hypergravity_10xg_downregulated
      WBPaper00061274:hypergravity_15xg_downregulated
      WBPaper00061340:ADL
      WBPaper00061340:AMsh
      WBPaper00061340:AMso
      WBPaper00061340:Anterior_arcade_cell
      WBPaper00061340:Arcade_cell_anterior_and_posterior
      WBPaper00061340:g1A
      WBPaper00061340:g1P
      WBPaper00061340:hyp3
      WBPaper00061340:ILsh_OLLsh_OLQsh
      WBPaper00061340:ILso
      WBPaper00061340:Posterior_arcade_cell
      WBPaper00061340:XXX
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061377:MYRF-1_interacting
      WBPaper00061422:let-607(RNAi)_regulated
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061479:hda-1(ne4752)_upregulated
      WBPaper00061479:HDA-1_interacting_protein
      WBPaper00061479:mep-1(ne4629)_upregulated
      WBPaper00061527:sdz-8-gst-31
      WBPaper00061572:oleic-acid-specific_mating_downregulated
      WBPaper00061590:CGP37157_upregulated
      WBPaper00061651:ADL_enriched
      WBPaper00061651:AIN_enriched
      WBPaper00061651:AMso_enriched
      WBPaper00061651:ASG_enriched
      WBPaper00061651:AVA_enriched
      WBPaper00061651:AVE_enriched
      WBPaper00061651:AVG_enriched
      WBPaper00061651:CEPsh_enriched
      WBPaper00061651:CEP_enriched
      WBPaper00061651:Coelomocyte_enriched
      WBPaper00061651:Excretory_gland_cell_enriched
      WBPaper00061651:FLP_enriched
      WBPaper00061651:I1_enriched
      WBPaper00061651:I2_enriched
      WBPaper00061651:I3_enriched
      WBPaper00061651:I4_enriched
      WBPaper00061651:I6_enriched
      WBPaper00061651:IL2_LR_enriched
      WBPaper00061651:MC_enriched
      WBPaper00061651:MI_enriched
      WBPaper00061651:NSM_enriched
      WBPaper00061651:OLQ_enriched
      WBPaper00061651:PHA_enriched
      WBPaper00061651:PHB_enriched
      WBPaper00061651:URB_enriched
      WBPaper00061651:URY_enriched
      WBPaper00061902:camt-1(ok515)_regulated_RMG
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062305:P.brevicompactum_upregulated
      WBPaper00062345:bortezomib_4h_upregulated_N2
      WBPaper00062345:bortezomib_4h_upregulated_zip-1(jy13)
      WBPaper00062354:H.zoospora_6h_regulated
      WBPaper00062520:qui-1(db104)_upregulated
      WBPaper00062554:MAGU-2_interacting
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064107:lin-35(n745)_upregulated
      WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated
      WBPaper00064291:antimycin_upregulated
      WBPaper00064382:auxin_upregulated
      WBPaper00064727:daf-2(e1370)_upregulated
      WBPaper00064728:cpl-1(W32AY35A)_upregulated
      WBPaper00064769:him-17(me24)_upregulated
      WBPaper00064788:ketamine_upregulated
      WBPaper00064871:P.fluorescens_upregulated_AWA
      WBPaper00064871:PA14_upregulated_AWA
      WBPaper00064933:bcf-1(ylf1)_downregulated_transcript
      WBPaper00064992:Eugenol_downregulated
      WBPaper00065029:cadmium_upregulated
      WBPaper00065074:glna(-)_downregulated
      WBPaper00065288:mdt-15(tm2182)_downregulated
      WBPaper00065373:Cisplatin_upregulated_WT
      WBPaper00065841:5_1
      WBPaper00065849:ursolic-acid_regulated
      WBPaper00065945:epidermis-rpoa-2(-)_upregulated_protein
      WBPaper00065975:P-body_vs_oocyte_depleted
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066038:mip-1(how5)_upregulated
      WBPaper00066062:xrep-4(lax137)_upregulated
      cgc4489_group_3
      WBPaper00024393:strongly_regulated_dauer_genes
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00028482:PA14_upregulated
      WBPaper00028789:PA14_vs_OP50_upregulated_4hr
      WBPaper00028789:PA14_vs_OP50_upregulated_8hr
      WBPaper00030839:Embryo_Pan_Neuronal
      WBPaper00030985:Photorhabdus_luminescens_upregulated
      WBPaper00031003:0hr_muscle_depleted
      WBPaper00031003:total_muscle_depleted
      WBPaper00031184:acrylamide_upregulated
      WBPaper00031832:slr-2_regulated
      WBPaper00031850:mdt-15(RNAi)_downregulated
      WBPaper00032165:differentially_expressed_with_age_medoid_2
      WBPaper00034757:up_by_oxidative_stress
      WBPaper00035479:daf-16(RNAi)_downregulated
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00036286:Pattern_G
      WBPaper00037113:CPF_16C_up-regulated
      WBPaper00037695:WC_5-day
      WBPaper00037704:ABZ_up_regulated
      WBPaper00039851:HK_C_albicans_vs_HK_OP50
      WBPaper00039851:Live_C_albicans_vs_HK_OP50
      WBPaper00040184:hcf-1up_sir-2.1up_daf-2up
      WBPaper00040210:Chlorpyrifos_16C_regulated
      WBPaper00040210:Chlorpyrifos_24C_regulated
      WBPaper00040210:Chlorpyrifos_Diazinon_24C_regulated
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.5
      WBPaper00040821:Au-NP_regulated
      WBPaper00040823:alg-1(gk214)_upregulated
      WBPaper00040858:eQTL_regulated_old
      WBPaper00040963:Q100_up
      WBPaper00040963:Q200_up
      WBPaper00040963:TA300_up
      WBPaper00041002:HF_3d_0.2mM_Up
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041002:HF_11d_0.2mM_Up
      WBPaper00041002:HQ_3d_2.0mM_Up
      WBPaper00041174:environmental
      WBPaper00041174:genotypic
      WBPaper00041174:genotypic_and_environmental
      WBPaper00041211:RPW-24_Up
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_EtBr-exposed_51h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:control_vs_UVC-exposed_48h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00042258:DA1877_upregulated_GravidAdult
      WBPaper00043980:arsenic_upregulated
      WBPaper00044091:Bpseudomallei_induced_8h
      WBPaper00044091:Bpseudomallei_induced_12h
      WBPaper00045263:isp-1(qm150)_upregulated
      WBPaper00045263:nuo-6(qm200)_upregulated
      WBPaper00047021:MWCNT_upregulated
      WBPaper00047070:N2_starvation_upregulated
      WBPaper00047070:xpa-1_UV_upregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
      WBPaper00050767:Octopamine_induced
      WBPaper00053688:E.faecalis_downregulated
      WBPaper00055899:2,4-Dinitroanisole_regulated
      WBPaper00055899:nitrotriazolone_regulated
      WBPaper00057098:SiO2-nanoparticles_downregulated
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_SM
      [cgc6390]:Cluster_C
    Interaction (36)
  Map_info: Map: II Position: 3.13385 Error: 0.000177
    Positive: Positive_clone: R03D7 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (22)
  Remark: [email fromJoanna Daulby]
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene