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WormBase Tree Display for Gene: WBGene00001725

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Name Class

WBGene00001725EvidencePaper_evidenceWBPaper00003717
SMapS_parentSequenceY65B4BR
IdentityVersion1
NameCGC_namegrl-16Person_evidenceWBPerson83
Sequence_nameY65B4BR.6
Molecular_nameY65B4BR.6a
Y65B4BR.6a.1
CE25541
Y65B4BR.6b
CE33240
Y65B4BR.6b.1
Other_nameY65B4BR.mCurator_confirmedWBPerson1983
RemarkOld cosmid naming mapped via unique overlapping PCR_product on CDSs
CELE_Y65B4BR.6Accession_evidenceNDBBX284601
Public_namegrl-16
DB_infoDatabaseAceViewgene1B46
WormQTLgeneWBGene00001725
WormFluxgeneWBGene00001725
NDBlocus_tagCELE_Y65B4BR.6
PanthergeneCAEEL|WormBase=WBGene00001725|UniProtKB=H2L083
familyPTHR23261
NCBIgene171649
RefSeqproteinNM_182075.3
NM_058353.6
TREEFAMTREEFAM_IDTF315611
TrEMBLUniProtAccQ9N2Z3
H2L083
UniProt_GCRPUniProtAccH2L083
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:25WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classgrl
Allele (84)
StrainWBStrain00032865
RNASeq_FPKM (74)
Ortholog (21)
Paralog (32)
Structured_descriptionConcise_descriptiongrl-16 encodes, by alternative splicing, two hedgehog-like proteins withan N-terminal signal sequence, a central proline-rich low-complexityregion, and a C-terminal Ground-like (Grl) domain; the Grl domain ispredicted to form a cysteine-crosslinked protein involved inintercellular signalling, and it has subtle similarity to the N-terminalHedge domain of HEDGEHOG proteins.Paper_evidenceWBPaper00003717
WBPaper00026841
WBPaper00027263
Curator_confirmedWBPerson567
Date_last_updated05 Nov 2006 00:00:00
Automated_descriptionEnriched in several structures, including arc ant V; germ line; hypodermis; neurons; and rectal epithelial cell based on proteomic; tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; proteomic; and RNA-seq studies. Is affected by twenty-four chemicals including hydrogen sulfide; 1-methylnicotinamide; and nicotinic acid based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Ground-like domain.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSY65B4BR.6a
Y65B4BR.6b
Corresponding_CDS_historyY65B4BR.6c:wp272
Corresponding_transcriptY65B4BR.6a.1
Y65B4BR.6b.1
Other_sequence (97)
Associated_featureWBsf648911
WBsf663874
WBsf717443
WBsf982538
WBsf982539
WBsf982540
WBsf1009099
WBsf1009100
WBsf218920
Experimental_infoRNAi_resultWBRNAi00037711Inferred_automaticallyRNAi_primary
Expr_patternExpr4423
Expr1018184
Expr1031030
Expr1161350
Expr2012250
Expr2030486
Drives_constructWBCnstr00011985
WBCnstr00036736
Construct_productWBCnstr00036736
Microarray_results (23)
Expression_cluster (308)
InteractionWBInteraction000543998
Map_infoMapIPosition-18.9281Error0.004756
PositivePositive_cloneY65B4BRInferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00028754
WBPaper00031588
WBPaper00050709
WBPaper00062388
WBPaper00064105
Remarkground-like gene, contains ground-like domain, hedgehog-relatedPaper_evidenceWBPaper00003717
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene