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WormBase Tree Display for Gene: WBGene00001703

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Name Class

WBGene00001703EvidencePaper_evidenceWBPaper00003717
Person_evidenceWBPerson83
SMapS_parentSequenceT01B10
IdentityVersion1
NameCGC_namegrd-14Person_evidenceWBPerson83
Sequence_nameT01B10.2
Molecular_nameT01B10.2
T01B10.2.1
CE07456
Other_nameCELE_T01B10.2Accession_evidenceNDBBX284606
Public_namegrd-14
DB_infoDatabaseAceViewgeneXJ117
WormQTLgeneWBGene00001703
WormFluxgeneWBGene00001703
NDBlocus_tagCELE_T01B10.2
NCBIgene187934
RefSeqproteinNM_077040.8
TREEFAMTREEFAM_IDTF316923
TrEMBLUniProtAccO02153
UniProt_GCRPUniProtAccO02153
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:25WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classgrd
Allele (21)
StrainWBStrain00002906
WBStrain00002427
WBStrain00033064
RNASeq_FPKM (74)
Ortholog (19)
Paralog (24)
Structured_descriptionConcise_descriptiongrd-14 encodes a hedgehog-like protein, with an N-terminal signalsequence and a C-terminal Ground domain; the Ground domain is predictedto form a cysteine-crosslinked protein involved in intercellularsignalling, and it has subtle similarity to the N-terminal Hedge domainof HEDGEHOG proteins; GRD-14 is required for normal growth to full size,locomotion, and vulval morphogenesis; all of these requirements mayreflect common defects in cholesterol-dependent hedgehog-like signallingor in vesicle trafficking.Paper_evidenceWBPaper00003717
WBPaper00026841
WBPaper00027263
Curator_confirmedWBPerson567
Date_last_updated05 Nov 2006 00:00:00
Automated_descriptionExpressed in rectal epithelium.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDST01B10.2
Corresponding_CDS_historyT01B10.2:wp100
Corresponding_transcriptT01B10.2.1
Other_sequenceCBC11374_1
CJC04686_1
Associated_featureWBsf662375
WBsf236054
Experimental_infoRNAi_resultWBRNAi00077026Inferred_automaticallyRNAi_primary
WBRNAi00034990Inferred_automaticallyRNAi_primary
WBRNAi00077003Inferred_automaticallyRNAi_primary
WBRNAi00052067Inferred_automaticallyRNAi_primary
WBRNAi00017927Inferred_automaticallyRNAi_primary
Expr_patternChronogram1823
Expr4438
Expr6556
Expr6557
Expr1018924
Expr1155698
Expr2012228
Expr2030464
Drives_constructWBCnstr00003038
WBCnstr00004512
WBCnstr00012001
WBCnstr00036754
Construct_productWBCnstr00036754
Microarray_results (18)
Expression_cluster (317)
Interaction (143)
WBProcessWBbiopr:00000123
Map_infoMapXPosition0.093161Error0.002384
PositivePositive_cloneT01B10Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00003717
WBPaper00024393
WBPaper00026841
WBPaper00028754
WBPaper00031588
WBPaper00064105
Remarkgrd-14 contains ground domain only. grd-4 and grd-14 form a cluster, grd-4 and grd-14 are paralogous to the grd-3 and grd-13 clusterPaper_evidenceWBPaper00003717
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene