WormBase Tree Display for Gene: WBGene00001703

WBGene00001703 Evidence: Paper_evidence: WBPaper00003717
    Person_evidence: WBPerson83
  SMap: S_parent: Sequence: T01B10
  Identity: Version: 1
    Name: CGC_name: grd-14 Person_evidence: WBPerson83
      Sequence_name: T01B10.2
      Molecular_name: T01B10.2
        T01B10.2.1
        CE07456
      Other_name: CELE_T01B10.2 Accession_evidence: NDB BX284606
      Public_name: grd-14
    DB_info: Database: AceView gene XJ117
        WormQTL gene WBGene00001703
        WormFlux gene WBGene00001703
        NDB locus_tag CELE_T01B10.2
        NCBI gene 187934
        RefSeq protein NM_077040.8
        TREEFAM TREEFAM_ID TF316923
        TrEMBL UniProtAcc O02153
        UniProt_GCRP UniProtAcc O02153
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:25 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: grd
    Allele (21)
    Strain: WBStrain00002906
      WBStrain00002427
      WBStrain00033064
    RNASeq_FPKM (74)
    Ortholog (19)
    Paralog (24)
    Structured_description: Concise_description: grd-14 encodes a hedgehog-like protein, with an N-terminal signalsequence and a C-terminal Ground domain; the Ground domain is predictedto form a cysteine-crosslinked protein involved in intercellularsignalling, and it has subtle similarity to the N-terminal Hedge domainof HEDGEHOG proteins; GRD-14 is required for normal growth to full size,locomotion, and vulval morphogenesis; all of these requirements mayreflect common defects in cholesterol-dependent hedgehog-like signallingor in vesicle trafficking. Paper_evidence: WBPaper00003717
            WBPaper00026841
            WBPaper00027263
          Curator_confirmed: WBPerson567
          Date_last_updated: 05 Nov 2006 00:00:00
      Automated_description: Expressed in rectal epithelium. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: T01B10.2
    Corresponding_CDS_history: T01B10.2:wp100
    Corresponding_transcript: T01B10.2.1
    Other_sequence: CBC11374_1
      CJC04686_1
    Associated_feature: WBsf662375
      WBsf236054
  Experimental_info: RNAi_result: WBRNAi00077026 Inferred_automatically: RNAi_primary
      WBRNAi00034990 Inferred_automatically: RNAi_primary
      WBRNAi00077003 Inferred_automatically: RNAi_primary
      WBRNAi00052067 Inferred_automatically: RNAi_primary
      WBRNAi00017927 Inferred_automatically: RNAi_primary
    Expr_pattern: Chronogram1823
      Expr4438
      Expr6556
      Expr6557
      Expr1018924
      Expr1155698
      Expr2012228
      Expr2030464
    Drives_construct: WBCnstr00003038
      WBCnstr00004512
      WBCnstr00012001
      WBCnstr00036754
    Construct_product: WBCnstr00036754
    Microarray_results (18)
    Expression_cluster (317)
    Interaction: WBInteraction000119986
      WBInteraction000121110
      WBInteraction000122379
      WBInteraction000124336
      WBInteraction000127188
      WBInteraction000133360
      WBInteraction000134519
      WBInteraction000135342
      WBInteraction000135718
      WBInteraction000136357
      WBInteraction000136977
      WBInteraction000137858
      WBInteraction000138301
      WBInteraction000141145
      WBInteraction000141340
      WBInteraction000145818
      WBInteraction000146177
      WBInteraction000147390
      WBInteraction000147718
      WBInteraction000148874
      WBInteraction000149144
      WBInteraction000149668
      WBInteraction000156695
      WBInteraction000160043
      WBInteraction000164654
      WBInteraction000165059
      WBInteraction000170693
      WBInteraction000172321
      WBInteraction000172552
      WBInteraction000172619
      WBInteraction000177078
      WBInteraction000180879
      WBInteraction000185342
      WBInteraction000186351
      WBInteraction000190359
      WBInteraction000190600
      WBInteraction000190851
      WBInteraction000191218
      WBInteraction000191508
      WBInteraction000192657
      WBInteraction000193989
      WBInteraction000195103
      WBInteraction000195662
      WBInteraction000198830
      WBInteraction000204449
      WBInteraction000205575
      WBInteraction000207212
      WBInteraction000208575
      WBInteraction000208996
      WBInteraction000211662
      WBInteraction000212292
      WBInteraction000212669
      WBInteraction000218381
      WBInteraction000219144
      WBInteraction000223414
      WBInteraction000224718
      WBInteraction000225017
      WBInteraction000228460
      WBInteraction000232330
      WBInteraction000232342
      WBInteraction000233886
      WBInteraction000234564
      WBInteraction000234703
      WBInteraction000235336
      WBInteraction000243014
      WBInteraction000245506
      WBInteraction000247285
      WBInteraction000248214
      WBInteraction000250803
      WBInteraction000255938
      WBInteraction000257345
      WBInteraction000259077
      WBInteraction000272310
      WBInteraction000273761
      WBInteraction000278658
      WBInteraction000279001
      WBInteraction000280189
      WBInteraction000285677
      WBInteraction000290970
      WBInteraction000292208
      WBInteraction000294052
      WBInteraction000294218
      WBInteraction000294675
      WBInteraction000297337
      WBInteraction000303026
      WBInteraction000307680
      WBInteraction000308012
      WBInteraction000309924
      WBInteraction000311297
      WBInteraction000312512
      WBInteraction000313704
      WBInteraction000314871
      WBInteraction000316086
      WBInteraction000316229
      WBInteraction000341582
      WBInteraction000346986
      WBInteraction000348606
      WBInteraction000352624
      WBInteraction000355452
      WBInteraction000355858
      WBInteraction000355995
      WBInteraction000363033
      WBInteraction000365728
      WBInteraction000367995
      WBInteraction000368690
      WBInteraction000371504
      WBInteraction000373162
      WBInteraction000377296
      WBInteraction000378966
      WBInteraction000379875
      WBInteraction000381188
      WBInteraction000382786
      WBInteraction000383006
      WBInteraction000384997
      WBInteraction000389423
      WBInteraction000392708
      WBInteraction000393792
      WBInteraction000394121
      WBInteraction000395296
      WBInteraction000396103
      WBInteraction000401053
      WBInteraction000402468
      WBInteraction000409061
      WBInteraction000412249
      WBInteraction000414000
      WBInteraction000415548
      WBInteraction000415679
      WBInteraction000420022
      WBInteraction000421179
      WBInteraction000421618
      WBInteraction000422627
      WBInteraction000423610
      WBInteraction000425769
      WBInteraction000425849
      WBInteraction000428119
      WBInteraction000431504
      WBInteraction000435554
      WBInteraction000442218
      WBInteraction000454300
      WBInteraction000456517
      WBInteraction000461791
      WBInteraction000552841
      WBInteraction000555118
    WBProcess: WBbiopr:00000123
  Map_info: Map: X Position: 0.093161 Error: 0.002384
    Positive: Positive_clone: T01B10 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00003717
    WBPaper00024393
    WBPaper00026841
    WBPaper00028754
    WBPaper00031588
    WBPaper00064105
  Remark: grd-14 contains ground domain only. grd-4 and grd-14 form a cluster, grd-4 and grd-14 are paralogous to the grd-3 and grd-13 cluster Paper_evidence: WBPaper00003717
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene