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WormBase Tree Display for Gene: WBGene00001645

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Name Class

WBGene00001645EvidencePerson_evidenceWBPerson2558
SMapS_parentSequenceC03E10
IdentityVersion1
NameCGC_namegly-20Person_evidenceWBPerson228
Sequence_nameC03E10.4
Molecular_nameC03E10.4
C03E10.4.1
CE26613
Other_nameGnT IIPaper_evidenceWBPaper00005572
CELE_C03E10.4Accession_evidenceNDBBX284605
Public_namegly-20
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:25WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classgly
Allele (46)
StrainWBStrain00031654
RNASeq_FPKM (74)
GO_annotation (17)
Ortholog (38)
Structured_descriptionConcise_descriptiongly-20 encodes an N-acetylglucosaminyltransferase II (GnTII); by homology, GLY-20 is predicted to function in the Golgi to effect protein N-glycosylation; expression of C. elegans GLY-20 and bovine beta1,4-galactosyltransferase I in a baculoviral insect cell system results in efficient glycosylation of mammalian proteins.Paper_evidenceWBPaper00040952
Curator_confirmedWBPerson1843
WBPerson1823
WBPerson567
Date_last_updated10 Apr 2012 00:00:00
Automated_descriptionPredicted to enable alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity. Involved in protein N-linked glycosylation. Predicted to be located in Golgi membrane. Used to study carbohydrate metabolic disorder. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIa. Is an ortholog of human MGAT2 (alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoExperimental_modelDOID:2978Homo sapiensPaper_evidenceWBPaper00064167
Curator_confirmedWBPerson324
Date_last_updated10 May 2023 00:00:00
Potential_modelDOID:0070253Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7045)
Models_disease_in_annotationWBDOannot00000055
Molecular_infoCorresponding_CDSC03E10.4
Corresponding_CDS_historyC03E10.4:wp31
Corresponding_transcriptC03E10.4.1
Other_sequence (34)
Associated_featureWBsf1001312
WBsf232490
WBsf232491
Experimental_infoRNAi_resultWBRNAi00039526Inferred_automaticallyRNAi_primary
WBRNAi00010055Inferred_automaticallyRNAi_primary
Expr_patternExpr1028272
Expr1030985
Expr1143626
Expr2012141
Expr2030377
Drives_constructWBCnstr00036801
Construct_productWBCnstr00036801
Microarray_results (22)
Expression_cluster (123)
Interaction (31)
Map_infoMapVPosition3.05492Error0.002457
PositivePositive_cloneC03E10Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4225
4365
Pseudo_map_position
Reference (14)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene