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WormBase Tree Display for Gene: WBGene00001621

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Name Class

WBGene00001621EvidencePerson_evidenceWBPerson402
WBPerson145
SMapS_parentSequenceK08F4
IdentityVersion1
NameCGC_nameglt-3
Sequence_nameK08F4.4
Molecular_nameK08F4.4
K08F4.4.1
CE06152
Other_nameCELE_K08F4.4Accession_evidenceNDBBX284604
Public_nameglt-3
DB_infoDatabaseAceViewgene4K897
WormQTLgeneWBGene00001621
WormFluxgeneWBGene00001621
NDBlocus_tagCELE_K08F4.4
PanthergeneCAEEL|WormBase=WBGene00001621|UniProtKB=Q21353
familyPTHR11958
NCBIgene177882
RefSeqproteinNM_069443.6
SwissProtUniProtAccQ21353
UniProt_GCRPUniProtAccQ21353
OMIMgene600300
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:25WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classglt
Allele (40)
Strain (12)
RNASeq_FPKM (74)
GO_annotation (12)
Ortholog (35)
ParalogWBGene00001620Caenorhabditis elegansFrom_analysisInparanoid_8
Panther
WormBase-Compara
WBGene00001624Caenorhabditis elegansFrom_analysisInparanoid_8
Panther
WormBase-Compara
WBGene00001625Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
WBGene00001623Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00001622Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionglt-3 encodes an ortholog of glutamate/aspartate and neutral amino acid transporters.Paper_evidenceWBPaper00004424
WBPaper00013304
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable L-glutamate transmembrane transporter activity; glutamate:sodium symporter activity; and neutral L-amino acid transmembrane transporter activity. Predicted to be involved in L-glutamate transmembrane transport. Predicted to be located in plasma membrane. Expressed in excretory cell and pharynx. Used to study neurodegenerative disease. Human ortholog(s) of this gene implicated in Huntington's disease; amyotrophic lateral sclerosis; and developmental and epileptic encephalopathy 41. Is an ortholog of human SLC1A2 (solute carrier family 1 member 2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoExperimental_modelDOID:1289Homo sapiensPaper_evidenceWBPaper00046048
WBPaper00032397
Curator_confirmedWBPerson324
WBPerson38202
Date_last_updated23 May 2018 00:00:00
Potential_modelDOID:332Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10940)
DOID:12858Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10940)
DOID:0080442Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10940)
Models_disease_in_annotationWBDOannot00000342
Models_disease_assertedWBDOannot00000528
Molecular_infoCorresponding_CDSK08F4.4
Corresponding_transcriptK08F4.4.1
Other_sequence (25)
Associated_featureWBsf646283
WBsf228936
Experimental_infoRNAi_resultWBRNAi00050321Inferred_automaticallyRNAi_primary
WBRNAi00016829Inferred_automaticallyRNAi_primary
WBRNAi00034152Inferred_automaticallyRNAi_primary
Expr_patternExpr4788
Expr1021850
Expr1030973
Expr1154023
Expr2012127
Expr2030363
Drives_constructWBCnstr00012245
WBCnstr00020300
WBCnstr00020301
WBCnstr00020302
WBCnstr00020996
WBCnstr00036818
Construct_productWBCnstr00012245
WBCnstr00036818
Microarray_results (20)
Expression_cluster (109)
Interaction (18)
Map_infoMapIVPosition4.53186Error0.000965
PositivePositive_cloneK08F4Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (14)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene