WormBase Tree Display for Gene: WBGene00001580
expand all nodes | collapse all nodes | view schema
| WBGene00001580 | SMap | S_parent | Sequence | CHROMOSOME_IV | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | gex-3 | Person_evidence | WBPerson419 | |||||
| Sequence_name | F28D1.10 | ||||||||
| Molecular_name | F28D1.10 | ||||||||
| F28D1.10.1 | |||||||||
| CE05750 | |||||||||
| Other_name | CELE_F28D1.10 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | gex-3 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:25 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | gex | ||||||||
| Allele (48) | |||||||||
| Strain | WBStrain00040419 | ||||||||
| WBStrain00024269 | |||||||||
| WBStrain00051117 | |||||||||
| WBStrain00055525 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (26) | |||||||||
| Ortholog (44) | |||||||||
| Structured_description | Concise_description | The gex-3 gene encodes a homolog of NAP1/NCKAP1, a mammalian protein ligand of the small GTPase Rac1, and of Drosophila HEM2/NAP1/KETTE; gex-3 is required for tissue morphogenesis and cell migrations; in gex-3 mutants, cells differentiate properly but fail to become organized. | Paper_evidence | WBPaper00005149 | |||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Involved in several processes, including egg-laying behavior; embryonic morphogenesis; and positive regulation of cellular component organization. Located in cell junction. Part of SCAR complex. Expressed in intestinal cell. Human ortholog(s) of this gene implicated in immunodeficiency 72. Is an ortholog of human NCKAP1 (NCK associated protein 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0112015 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4862) | ||||
| Molecular_info | Corresponding_CDS | F28D1.10 | |||||||
| Corresponding_transcript | F28D1.10.1 | ||||||||
| Other_sequence (40) | |||||||||
| Associated_feature | WBsf646473 | ||||||||
| WBsf229287 | |||||||||
| WBsf229288 | |||||||||
| Experimental_info | RNAi_result (41) | ||||||||
| Expr_pattern | Expr1828 | ||||||||
| Expr8395 | |||||||||
| Expr10794 | |||||||||
| Expr12485 | |||||||||
| Expr1017668 | |||||||||
| Expr1030946 | |||||||||
| Expr1149732 | |||||||||
| Expr2012024 | |||||||||
| Expr2030260 | |||||||||
| Drives_construct | WBCnstr00013296 | ||||||||
| WBCnstr00036848 | |||||||||
| Construct_product | WBCnstr00009364 | ||||||||
| WBCnstr00013296 | |||||||||
| WBCnstr00017546 | |||||||||
| WBCnstr00036848 | |||||||||
| Antibody | WBAntibody00000464 | ||||||||
| Microarray_results (22) | |||||||||
| Expression_cluster (120) | |||||||||
| Interaction (100) | |||||||||
| Map_info | Positive | Positive_clone | F28D1 | Inferred_automatically | From CDS info | ||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4816 | |||||||
| Interpolated_map_position | IV | 5.91283 | |||||||
| Reference (37) | |||||||||
| Remark | most on F28D1.10; the 3' end on F08G5 (nucleotides 1 to 4576). predicted gene previously called CeHEM2; mammalian homolog is called HEM2 and NAP1, and the fly homolog is called KETTE. [Soto M] | ||||||||
| Method | Gene |
