WormBase Tree Display for Gene: WBGene00001561
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| WBGene00001561 | Evidence | CGC_data_submission | |||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | W07B3 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | gei-4 | Person_evidence | WBPerson1796 | |||||
| Sequence_name | W07B3.2 | ||||||||
| Molecular_name (22) | |||||||||
| Other_name | W07B3.a | Curator_confirmed | WBPerson1983 | ||||||
| Remark | Old cosmid naming mapped via unique overlapping PCR_product on CDSs | ||||||||
| W07B3.b | Curator_confirmed | WBPerson1983 | |||||||
| Remark | Old cosmid naming mapped via unique overlapping PCR_product on CDSs | ||||||||
| CELE_W07B3.2 | Accession_evidence | NDB | BX284603 | ||||||
| Public_name | gei-4 | ||||||||
| DB_info | Database | AceView | gene | 3A962 | |||||
| WormQTL | gene | WBGene00001561 | |||||||
| WormFlux | gene | WBGene00001561 | |||||||
| NDB | locus_tag | CELE_W07B3.2 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00001561|UniProtKB=H2L0F6 | |||||||
| family | PTHR22084 | ||||||||
| NCBI | gene | 175195 | |||||||
| RefSeq | protein | NM_001393253.1 | |||||||
| NM_001381690.2 | |||||||||
| NM_001384004.2 | |||||||||
| NM_001027640.5 | |||||||||
| NM_064789.6 | |||||||||
| NM_001393254.1 | |||||||||
| TREEFAM | TREEFAM_ID | TF319602 | |||||||
| TrEMBL | UniProtAcc | H2L0F5 | |||||||
| H2L0F8 | |||||||||
| H2L0F6 | |||||||||
| Q65CL5 | |||||||||
| Q8ITW3 | |||||||||
| H2L0F7 | |||||||||
| UniProt_GCRP | UniProtAcc | H2L0F6 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:24 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | gei | ||||||||
| Allele (233) | |||||||||
| Strain | WBStrain00037773 | ||||||||
| WBStrain00037797 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00023031 | ||||||||
| 00023032 | |||||||||
| 00023033 | |||||||||
| 00023034 | |||||||||
| 00023035 | |||||||||
| 00023036 | |||||||||
| Contained_in_operon | CEOP3023 | ||||||||
| Ortholog (29) | |||||||||
| Paralog | WBGene00021756 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00021986 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | gei-4 encodes a protein with a coiled-coil domain (predicted to mediate protein-protein interactions), an internal repeat of 69 residues (covering residues 134-202, 203-265, and 266-328 of W07B3.2a), and a glutamine/asparagine-rich domain; GEI-4 is paralogous to Y50D7A.8 and Y59C2A.3, physically interacts with GEX-2, and is required for embryonic viability, fertility, and vulval morphogenesis; GEI-4 is claimed to have weak homology to trichohyalin, a mammalian intermediate filament interacting protein; the similarity of the mutant phenotypes of gei-4, gex-2 and gex-3 and their interaction sugggest that the GEX-2/GEX-3/GEI-4 protein complex is essential for the regulation of intermediate filaments during rearrangement of the cytoskeleton that occurs in embryogenesis; GFI-2, an ankyrin-repeat protein associates with GEI-4 and exhibits a similar mutant phenotype, suggesting that gfi-2 is also involved in intermediate filament dynamics. | Paper_evidence | WBPaper00005068 | |||||
| WBPaper00005194 | |||||||||
| WBPaper00005654 | |||||||||
| WBPaper00012788 | |||||||||
| WBPaper00012830 | |||||||||
| WBPaper00012882 | |||||||||
| WBPaper00012897 | |||||||||
| WBPaper00013003 | |||||||||
| WBPaper00018044 | |||||||||
| WBPaper00018124 | |||||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Involved in negative regulation of Ras protein signal transduction and negative regulation of vulval development. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | W07B3.2a | |||||||
| W07B3.2b | |||||||||
| W07B3.2c | |||||||||
| W07B3.2d | |||||||||
| W07B3.2e | |||||||||
| W07B3.2f | |||||||||
| Corresponding_CDS_history | W07B3.2c:wp102 | ||||||||
| W07B3.2d:wp187 | |||||||||
| Corresponding_transcript | W07B3.2a.1 | ||||||||
| W07B3.2a.2 | |||||||||
| W07B3.2b.1 | |||||||||
| W07B3.2b.2 | |||||||||
| W07B3.2c.1 | |||||||||
| W07B3.2c.2 | |||||||||
| W07B3.2d.1 | |||||||||
| W07B3.2d.2 | |||||||||
| W07B3.2e.1 | |||||||||
| W07B3.2f.1 | |||||||||
| Other_sequence (51) | |||||||||
| Associated_feature (20) | |||||||||
| Experimental_info | RNAi_result (38) | ||||||||
| Expr_pattern | Expr1017902 | ||||||||
| Expr1030931 | |||||||||
| Expr1158474 | |||||||||
| Expr2012015 | |||||||||
| Expr2030251 | |||||||||
| Microarray_results (59) | |||||||||
| Expression_cluster (149) | |||||||||
| Interaction (230) | |||||||||
| Map_info | Map | III | Position | -26.893 | Error | 0.002195 | |||
| Positive | Positive_clone | W07B3 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (11) | |||||||||
| Remark | Sequence connection from [Qadota H, Kaibuchi K] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
