WormBase Tree Display for Gene: WBGene00001535
expand all nodes | collapse all nodes | view schema
| WBGene00001535 | SMap | S_parent | Sequence | C49H3 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | gcy-8 | Person_evidence | WBPerson655 | |||||
| Sequence_name | C49H3.1 | ||||||||
| Molecular_name | C49H3.1 | ||||||||
| C49H3.1.1 | |||||||||
| CE42080 | |||||||||
| Other_name | CELE_C49H3.1 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | gcy-8 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:24 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | gcy | ||||||||
| Allele (54) | |||||||||
| Legacy_information | [Yu S] gcy for Guanylyl CYclase. No mutations known. gcy-8::GFP expressed only in AFD. Predicted gene C49H3.2 | ||||||||
| Strain | WBStrain00031124 | ||||||||
| WBStrain00031127 | |||||||||
| WBStrain00031134 | |||||||||
| WBStrain00022003 | |||||||||
| WBStrain00022015 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (38) | |||||||||
| Ortholog (35) | |||||||||
| Paralog (37) | |||||||||
| Structured_description | Concise_description | gcy-8 encodes a receptor-type guanylyl cyclase that, along with gcy-18 and gcy-23, constitutes a subfamily of guanylyl cyclase genes in C. elegans; gcy-8 functions redundantly with gcy-18 and gcy-23, and upstream of tax-4, to regulate thermotaxis via the AFD thermosensory neurons, although of the three guanylyl cyclases required, genetic analyses suggest that GCY-18 is the primary guanylyl cyclase required; GCY-8 is expressed exclusively in the AFD thermosensory neurons where it localizes to sensory endings; GCY-8 expression in the AFD neurons requires activity of the TAX-2/4 cyclic nucleotide gated channel and the CMK-1 Ca2+/calmodulin-dependent protein kinase I, while maintenance of GCY-8 expression requires the OTD/OTX homeodomain protein TTX-1. | Paper_evidence | WBPaper00002839 | |||||
| WBPaper00004879 | |||||||||
| WBPaper00006343 | |||||||||
| WBPaper00027040 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 07 Aug 2006 00:00:00 | ||||||||
| Automated_description | Enables guanylate cyclase activity. Involved in microvillus organization and response to temperature stimulus. Located in microvillus membrane and neuron projection terminus. Expressed in AFDL and AFDR. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | C49H3.1 | |||||||
| Corresponding_CDS_history | C49H3.1:wp187 | ||||||||
| Corresponding_transcript | C49H3.1.1 | ||||||||
| Other_sequence (14) | |||||||||
| Associated_feature | WBsf646129 | ||||||||
| WBsf980902 | |||||||||
| WBsf980903 | |||||||||
| WBsf228598 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00042833 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00012164 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00103221 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00012161 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00029995 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00042832 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern (12) | |||||||||
| Drives_construct (41) | |||||||||
| Construct_product | WBCnstr00011696 | ||||||||
| WBCnstr00018503 | |||||||||
| WBCnstr00036879 | |||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (102) | |||||||||
| Interaction (30) | |||||||||
| Map_info | Map | IV | Position | 3.50015 | Error | 0.000609 | |||
| Positive | Positive_clone | C49H3 | Person_evidence | WBPerson4049 | |||||
| Inferred_automatically | From sequence, transcript, pseudogene data | ||||||||
| Mapping_data | Multi_point | 4941 | |||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00002821 | ||||||||
| WBPaper00002839 | |||||||||
| WBPaper00002846 | |||||||||
| WBPaper00003977 | |||||||||
| WBPaper00004379 | |||||||||
| WBPaper00004879 | |||||||||
| WBPaper00005236 | |||||||||
| WBPaper00006045 | |||||||||
| WBPaper00006146 | |||||||||
| WBPaper00006343 | |||||||||
| WBPaper00010048 | |||||||||
| WBPaper00010095 | |||||||||
| WBPaper00010328 | |||||||||
| WBPaper00011352 | |||||||||
| WBPaper00011862 | |||||||||
| WBPaper00011900 | |||||||||
| WBPaper00015584 | |||||||||
| WBPaper00015738 | |||||||||
| WBPaper00017003 | |||||||||
| WBPaper00017590 | |||||||||
| WBPaper00018026 | |||||||||
| WBPaper00018199 | |||||||||
| WBPaper00018556 | |||||||||
| WBPaper00019470 | |||||||||
| WBPaper00023281 | |||||||||
| WBPaper00023609 | |||||||||
| WBPaper00023611 | |||||||||
| WBPaper00023622 | |||||||||
| WBPaper00025390 | |||||||||
| WBPaper00027040 | |||||||||
| WBPaper00027258 | |||||||||
| WBPaper00030500 | |||||||||
| WBPaper00031681 | |||||||||
| WBPaper00031874 | |||||||||
| WBPaper00032060 | |||||||||
| WBPaper00034186 | |||||||||
| WBPaper00034491 | |||||||||
| WBPaper00034534 | |||||||||
| WBPaper00037256 | |||||||||
| WBPaper00038137 | |||||||||
| WBPaper00039396 | |||||||||
| WBPaper00039694 | |||||||||
| WBPaper00043363 | |||||||||
| WBPaper00043863 | |||||||||
| WBPaper00044335 | |||||||||
| WBPaper00044794 | |||||||||
| WBPaper00045913 | |||||||||
| WBPaper00046292 | |||||||||
| WBPaper00046365 | |||||||||
| WBPaper00046614 | |||||||||
| WBPaper00047708 | |||||||||
| WBPaper00048088 | |||||||||
| WBPaper00048100 | |||||||||
| WBPaper00048426 | |||||||||
| WBPaper00049423 | |||||||||
| WBPaper00050219 | |||||||||
| WBPaper00052542 | |||||||||
| WBPaper00052694 | |||||||||
| WBPaper00052828 | |||||||||
| WBPaper00053740 | |||||||||
| WBPaper00058304 | |||||||||
| WBPaper00058402 | |||||||||
| WBPaper00059582 | |||||||||
| WBPaper00059949 | |||||||||
| WBPaper00060238 | |||||||||
| WBPaper00061198 | |||||||||
| WBPaper00061818 | |||||||||
| WBPaper00061932 | |||||||||
| WBPaper00064039 | |||||||||
| WBPaper00064732 | |||||||||
| WBPaper00065330 | |||||||||
| WBPaper00065541 | |||||||||
| Remark | Data extracted from Yu et al. (1997) | ||||||||
| C49H3.2 is dead merged into .1 [sdm 11.2000] | |||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
