WormBase Tree Display for Gene: WBGene00001465
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| WBGene00001465 | SMap | S_parent | Sequence | F02D10 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | flr-1 | Person_evidence | WBPerson309 | |||||
| Sequence_name | F02D10.5 | ||||||||
| Molecular_name | F02D10.5 | ||||||||
| F02D10.5.1 | |||||||||
| CE27118 | |||||||||
| Other_name | CELE_F02D10.5 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | flr-1 | ||||||||
| DB_info | Database | AceView | gene | XO72 | |||||
| WormQTL | gene | WBGene00001465 | |||||||
| WormFlux | gene | WBGene00001465 | |||||||
| NDB | locus_tag | CELE_F02D10.5 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00001465|UniProtKB=G5EGI5 | |||||||
| family | PTHR11690 | ||||||||
| NCBI | gene | 181468 | |||||||
| RefSeq | protein | NM_077842.5 | |||||||
| TrEMBL | UniProtAcc | G5EGI5 | |||||||
| UniProt_GCRP | UniProtAcc | G5EGI5 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:24 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | flr | ||||||||
| Allele (69) | |||||||||
| Legacy_information | [Katsura I] Resistant to 400 5g/ml NaF. Slow growth. Small | ||||||||
| [Thomas JH] very short defecation cycle period, often with weak or missing motor program steps, Con, scrawny and slow growing, fluoride resistant.appears to feed normally | |||||||||
| [C.elegansII] ut1 : resistant to 400 ug/ml NaF. Slow growth. Small. OA5: ut2, ut4, ut6, ut11, sa96 (very short defecation cycle period, often with weak or missing motor program steps, Con, scrawny and slow growing, fluoride resistant; appears to feed normally). Cloned: encodes protein with some similarity to DEG-1/MEC-4 family. [Katsura et al. 1994; Iwasaki et al. 1995; JC; JT] | |||||||||
| Strain | WBStrain00022185 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (19) | |||||||||
| Ortholog (43) | |||||||||
| Paralog (30) | |||||||||
| Structured_description | Concise_description | flr-1 encodes an ion channel that belongs to the DEG/ENaC sodium channel superfamily; flr-1 activity is essential for normal defecation rhythm, growth rates, expulsion, and dauer larvae formation; a rescuing FLR-1::GFP reporter is expressed in the intestine from embryonic to adult stages where it localizes to the membranes facing the inner lumen as well as to part of the lateral membrane between intestinal cells. | Paper_evidence | WBPaper00001854 | |||||
| WBPaper00003219 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 13 Jun 2007 00:00:00 | ||||||||
| Automated_description | Predicted to enable ligand-gated sodium channel activity. Involved in defecation and ultradian rhythm. Located in nuclear membrane and plasma membrane. Is an ortholog of human ASIC1 (acid sensing ion channel subunit 1); ASIC2 (acid sensing ion channel subunit 2); and ASIC3 (acid sensing ion channel subunit 3). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F02D10.5 | |||||||
| Corresponding_CDS_history | F02D10.5:wp40 | ||||||||
| Corresponding_transcript | F02D10.5.1 | ||||||||
| Other_sequence | AB012617 | ||||||||
| Oden_isotig17752 | |||||||||
| CBC01437_1 | |||||||||
| Dviv_isotig10409 | |||||||||
| Associated_feature | WBsf654528 | ||||||||
| WBsf654529 | |||||||||
| WBsf238139 | |||||||||
| Experimental_info | RNAi_result (20) | ||||||||
| Expr_pattern | Expr529 | ||||||||
| Expr9282 | |||||||||
| Expr1012673 | |||||||||
| Expr1147779 | |||||||||
| Expr2011852 | |||||||||
| Expr2030090 | |||||||||
| Drives_construct (17) | |||||||||
| Construct_product (13) | |||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (77) | |||||||||
| Interaction (12) | |||||||||
| Map_info | Map | X | Position | 12.5766 | Error | 0.021117 | |||
| Well_ordered | |||||||||
| Positive | Positive_clone | F02D10 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | 2_point | 6160 | |||||||
| 6161 | |||||||||
| 6162 | |||||||||
| Multi_point | 2411 | ||||||||
| 3255 | |||||||||
| 3256 | |||||||||
| 3257 | |||||||||
| 3817 | |||||||||
| 3818 | |||||||||
| 4276 | |||||||||
| 4311 | |||||||||
| Pos_neg_data | 7060 | ||||||||
| 7061 | |||||||||
| 7062 | |||||||||
| 7063 | |||||||||
| 7064 | |||||||||
| 8432 | |||||||||
| Reference (39) | |||||||||
| Remark | [ Katsura I] flr stands for fluoride-resistant | ||||||||
| flr-1 is F02D10.5 based on sequence match with EMBL accession AB012617 from dl1. 200101 | |||||||||
| Method | Gene |
