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WormBase Tree Display for Gene: WBGene00001404

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Name Class

WBGene00001404SMapS_parentSequenceK07A3
IdentityVersion1
NameCGC_namefbp-1
Sequence_nameK07A3.1
Molecular_nameK07A3.1a
K07A3.1a.1
CE21023
K07A3.1b
Other_namefbpAccession_evidenceEMBLAJ271466
CELE_K07A3.1Accession_evidenceNDBBX284601
Public_namefbp-1
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:24WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classfbp
Allele (171)
StrainWBStrain00001692
WBStrain00047459
RNASeq_FPKM (74)
GO_annotation (17)
Ortholog (43)
Structured_descriptionConcise_descriptionfbp-1 encodes fructose 1,6-bisphosphatase, a gluconeogenic enzyme that catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate in a reaction that reverses the third enzymatic step of glycolysis; FBP-1 is orthologous to human FBP1 (OMIM:229700, mutated in FBP deficiency).Paper_evidenceWBPaper00004402
Curator_confirmedWBPerson1843
WBPerson1823
WBPerson567
Date_last_updated26 Oct 2011 00:00:00
Automated_descriptionPredicted to enable fructose 1,6-bisphosphate 1-phosphatase activity. Predicted to be involved in carbohydrate metabolic process and organophosphate metabolic process. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in fructose-1,6-bisphosphatase deficiency. Is an ortholog of human FBP1 (fructose-bisphosphatase 1) and FBP2 (fructose-bisphosphatase 2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:5204Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3606)
Molecular_infoCorresponding_CDSK07A3.1a
Corresponding_CDS_historyK07A3.1b:wp124
Corresponding_transcriptK07A3.1b
K07A3.1a.1
Other_sequence (154)
Associated_featureWBsf648977
WBsf663954
WBsf982910
WBsf219044
WBsf219045
WBsf219046
WBsf219047
Experimental_infoRNAi_resultWBRNAi00092277Inferred_automaticallyRNAi_primary
WBRNAi00003953Inferred_automaticallyRNAi_primary
WBRNAi00092278Inferred_automaticallyRNAi_primary
WBRNAi00034040Inferred_automaticallyRNAi_primary
WBRNAi00050103Inferred_automaticallyRNAi_primary
WBRNAi00116494Inferred_automaticallyRNAi_primary
Expr_patternChronogram987
Expr6341
Expr1017608
Expr1030841
Expr1153805
Expr2011447
Expr2029685
Drives_constructWBCnstr00002516
WBCnstr00004367
WBCnstr00036966
Construct_productWBCnstr00036966
Microarray_results (25)
Expression_cluster (179)
Interaction (59)
Map_infoMapIPosition-8.30266Error0.02115
PositivePositive_cloneK07A3Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00026800
WBPaper00027145
WBPaper00029292
WBPaper00031648
WBPaper00038491
WBPaper00055090
WBPaper00060127
WBPaper00064339
WBPaper00064934
RemarkSequence connection from [Tillmann H, Bernhard D, Eshrich K] [040902 ck1]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene