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WormBase Tree Display for Gene: WBGene00001372

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Name Class

WBGene00001372SMapS_parentSequenceR09B3
IdentityVersion1
NameCGC_nameexo-3Person_evidenceWBPerson1551
Sequence_nameR09B3.1
Molecular_nameR09B3.1a
R09B3.1a.1
CE16306
R09B3.1b
CE38407
R09B3.1a.2
R09B3.1b.1
Other_nameCELE_R09B3.1Accession_evidenceNDBBX284601
Public_nameexo-3
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:24WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classexo
Allele (48)
StrainWBStrain00033223
WBStrain00033229
RNASeq_FPKM (74)
GO_annotation (24)
Contained_in_operonCEOP1656
Ortholog (33)
Structured_descriptionConcise_descriptionexo-3 encodes an ortholog of human APEX/REF1 and rat apurinic/apyrimidinic endonuclease (AP endonuclease 1); EXO-3 is implicated in a DNA damage checkpoint pathway that affects embryonic and larval viability.Paper_evidenceWBPaper00005039
WBPaper00005599
Curator_confirmedWBPerson48
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionEnables DNA-(apurinic or apyrimidinic site) endonuclease activity and phosphoric diester hydrolase activity. Involved in base-excision repair; embryo development; and nematode larval development. Predicted to be located in nucleus. Expressed in hermaphrodite gonad and male gonad. Human ortholog(s) of this gene implicated in several diseases, including female reproductive organ cancer (multiple); prostate carcinoma in situ; and spina bifida. Is an ortholog of human APEX1 (apurinic/apyrimidinic endodeoxyribonuclease 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_model (11)
Molecular_infoCorresponding_CDSR09B3.1a
R09B3.1b
Corresponding_transcriptR09B3.1a.1
R09B3.1a.2
R09B3.1b.1
Other_sequence (28)
Associated_featureWBsf047562
WBsf220375
Experimental_infoRNAi_result (11)
Expr_patternExpr12286
Expr14296
Expr1019771
Expr1030827
Expr1155260
Expr2011397
Expr2029633
Microarray_results (25)
Expression_cluster (147)
Interaction (140)
Map_infoMapIPosition12.9229Error0.002952
PositivePositive_cloneR09B3Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (28)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene