WormBase Tree Display for Gene: WBGene00001235
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| WBGene00001235 | SMap | S_parent | Sequence | Y41C4A | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | elb-1 | Person_evidence | WBPerson322 | |||||
| Sequence_name | Y41C4A.10 | ||||||||
| Molecular_name | Y41C4A.10 | ||||||||
| Y41C4A.10.1 | |||||||||
| CE20250 | |||||||||
| Other_name | 3L686 | Accession_evidence | EMBL | AF326942 | |||||
| CELE_Y41C4A.10 | Accession_evidence | NDB | BX284603 | ||||||
| Public_name | elb-1 | ||||||||
| DB_info | Database | AceView | gene | 3M808 | |||||
| WormQTL | gene | WBGene00001235 | |||||||
| WormFlux | gene | WBGene00001235 | |||||||
| NDB | locus_tag | CELE_Y41C4A.10 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00001235|UniProtKB=G5ECR7 | |||||||
| family | PTHR13248 | ||||||||
| NCBI | gene | 176605 | |||||||
| RefSeq | protein | NM_067116.7 | |||||||
| TREEFAM | TREEFAM_ID | TF325964 | |||||||
| TrEMBL | UniProtAcc | G5ECR7 | |||||||
| UniProt_GCRP | UniProtAcc | G5ECR7 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:23 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | elb | ||||||||
| Allele (15) | |||||||||
| Strain | WBStrain00051184 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00012393 | ||||||||
| 00012394 | |||||||||
| 00012395 | |||||||||
| 00012396 | |||||||||
| 00012397 | |||||||||
| 00108490 | |||||||||
| 00108491 | |||||||||
| 00108492 | |||||||||
| Contained_in_operon | CEOP3728 | ||||||||
| Ortholog (33) | |||||||||
| Structured_description | Concise_description | elb-1 encodes an Elongin B ortholog required for chromosome condensationand segregation during mitosis and meiotic division II, and also for cellproliferation (probably through degradation of CKI-1); elb-1(RNAi) animalstend to arrest at the second meiotic cell division, with escapers showingmany other defects in chromosomal dynamics and cell cycle control such asabnormal pronuclear rotation and cortical protrusion, aberrant chromosomalstructures in the intestine, and deficient germ cell proliferation; ELB-1interacts with ELC-1 and ELC-2 in bacterial two-hybrid experiments. | Paper_evidence | WBPaper00026616 | |||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 23 Aug 2006 00:00:00 | ||||||||
| Automated_description | Enables protein domain specific binding activity. Predicted to be involved in transcription elongation by RNA polymerase II. Part of Cul2-RING ubiquitin ligase complex. Is an ortholog of human ELOB (elongin B). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | Y41C4A.10 | |||||||
| Corresponding_transcript | Y41C4A.10.1 | ||||||||
| Other_sequence | AF326942 | ||||||||
| CBC12953_1 | |||||||||
| CRC11177_1 | |||||||||
| Associated_feature | WBsf651515 | ||||||||
| WBsf994473 | |||||||||
| WBsf227594 | |||||||||
| Experimental_info | RNAi_result (39) | ||||||||
| Expr_pattern | Expr1016832 | ||||||||
| Expr1030783 | |||||||||
| Expr1159837 | |||||||||
| Expr2011270 | |||||||||
| Expr2029506 | |||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (96) | |||||||||
| Interaction (76) | |||||||||
| Map_info | Map | III | Position | 12.0059 | Error | 0.028827 | |||
| Positive | Positive_clone | Y41C4A | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00024321 | ||||||||
| WBPaper00024458 | |||||||||
| WBPaper00026616 | |||||||||
| WBPaper00027315 | |||||||||
| WBPaper00030834 | |||||||||
| WBPaper00037728 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00041771 | |||||||||
| WBPaper00048493 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
