WormBase Tree Display for Gene: WBGene00001210
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| WBGene00001210 | Evidence | CGC_data_submission | |||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | K11G9 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | egl-46 | Person_evidence | WBPerson268 | |||||
| Sequence_name | K11G9.4 | ||||||||
| Molecular_name | K11G9.4 | ||||||||
| K11G9.4.1 | |||||||||
| CE07377 | |||||||||
| Other_name | CELE_K11G9.4 | Accession_evidence | NDB | BX284605 | |||||
| Public_name | egl-46 | ||||||||
| DB_info | Database | AceView | gene | 5H160 | |||||
| WormQTL | gene | WBGene00001210 | |||||||
| WormFlux | gene | WBGene00001210 | |||||||
| NDB | locus_tag | CELE_K11G9.4 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00001210|UniProtKB=G5EFY4 | |||||||
| family | PTHR15065 | ||||||||
| NCBI | gene | 179058 | |||||||
| RefSeq | protein | NM_072293.7 | |||||||
| SwissProt | UniProtAcc | G5EFY4 | |||||||
| TREEFAM | TREEFAM_ID | TF320538 | |||||||
| UniProt_GCRP | UniProtAcc | G5EFY4 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:23 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | egl | ||||||||
| Reference_allele | WBVar00089969 | ||||||||
| Allele (62) | |||||||||
| Possibly_affected_by | WBVar02152827 | ||||||||
| Legacy_information | n1127 : moderate bloating Type B; HSN cell bodies do not contain serotonin. ES2 (adult) ES1 (other stages). NA4 (n1075 n1076 etc.). | ||||||||
| See also n1075, n1076, n1127 | |||||||||
| [C.elegansII] n1127 : moderate bloating; stimulated by serotonin, not imipramine; HSN cell bodies do not contain serotonin; torpid Unc and Lin (abnormal Q lineage) phenotypes; axon defects; serotonin levels increased if HSN synapse formation blocked. Ectopic expression of mec-7. n1127/Df similar. ES2 (adult) ES1 (other stages). ME2. OA3: n1075, n1076. [Desai and Horvitz 1989; MT; TU] | |||||||||
| Strain | WBStrain00026948 | ||||||||
| WBStrain00026949 | |||||||||
| WBStrain00026961 | |||||||||
| WBStrain00026962 | |||||||||
| WBStrain00027008 | |||||||||
| WBStrain00030930 | |||||||||
| WBStrain00036645 | |||||||||
| WBStrain00047495 | |||||||||
| WBStrain00052009 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (41) | |||||||||
| Ortholog (38) | |||||||||
| Structured_description | Concise_description | egl-46 encodes a transcription factor with similarity to the TFIIA-like zinc-finger protein family; egl-46 activity is required for coordinated locomotion, morphology and process formation of the touch cells, male mating efficiency, HSN cell migration, differentiation, and axonal outgrowth, serotonin production and also terminal divisions of the Q neuroblasts; egl-46 acts to inhibit touch cell fate in FLP cells together with egl-44; EGL-46 is a nuclear protein expressed dynamically in neurons, including the touch receptor neurons, ventral cord neurons, FLP, and HSN neurons; egl-46 expression in FLP cells, but not HSN cells, is dependent upon EGL-44. | Paper_evidence | WBPaper00001105 | |||||
| WBPaper00001133 | |||||||||
| WBPaper00001829 | |||||||||
| WBPaper00004624 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson1843 | |||||||||
| Date_last_updated | 17 Nov 2011 00:00:00 | ||||||||
| Automated_description | Enables RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in several processes, including detection of chemical stimulus; generation of neurons; and positive regulation of exit from mitosis. Located in nucleus. Expressed in several structures, including QL.aa; QL.pp; QR.aa; QR.pp; and neurons. Is an ortholog of human INSM2 (INSM transcriptional repressor 2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | K11G9.4 | |||||||
| Corresponding_transcript | K11G9.4.1 | ||||||||
| Other_sequence | CBC10186_1 | ||||||||
| EY464902.1 | |||||||||
| Oden_isotig29205 | |||||||||
| Dviv_isotig23700 | |||||||||
| ACC23330_1 | |||||||||
| EY466548.1 | |||||||||
| JI168880.1 | |||||||||
| EY472706.1 | |||||||||
| Associated_feature (14) | |||||||||
| Transcription_factor | WBTranscriptionFactor000162 | ||||||||
| Experimental_info | RNAi_result (15) | ||||||||
| Expr_pattern (12) | |||||||||
| Drives_construct (16) | |||||||||
| Construct_product | WBCnstr00013518 | ||||||||
| WBCnstr00018318 | |||||||||
| WBCnstr00037031 | |||||||||
| Microarray_results (22) | |||||||||
| Expression_cluster (254) | |||||||||
| Interaction (157) | |||||||||
| WBProcess | WBbiopr:00000024 | ||||||||
| WBbiopr:00000118 | |||||||||
| Map_info | Map | V | Position | 0.132676 | Error | 0.000364 | |||
| Well_ordered | |||||||||
| Positive | Positive_clone | K11G9 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 786 | |||||||
| 5058 | |||||||||
| Reference (51) | |||||||||
| Remark | Sequence connection from [Wu J, Duggan A, Chalfie M] | ||||||||
| Method | Gene |
