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WormBase Tree Display for Gene: WBGene00001193

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Name Class

WBGene00001193SMapS_parentSequenceC23H3
IdentityVersion1
NameCGC_nameegl-26Person_evidenceWBPerson268
Sequence_nameC23H3.1
Molecular_nameC23H3.1a
C23H3.1a.1
CE08320
C23H3.1b
CE50533
C23H3.1b.1
Other_nameegl-48
cog-4
CELE_C23H3.1Accession_evidenceNDBBX284602
Public_nameegl-26
DB_infoDatabaseAceViewgene2A377
WormQTLgeneWBGene00001193
WormFluxgeneWBGene00001193
NDBlocus_tagCELE_C23H3.1
PanthergeneCAEEL|EnsemblGenome=WBGene00001193|UniProtKB=P91082
familyPTHR36948
NCBIgene173392
RefSeqproteinNM_001313583.2
NM_061251.6
SwissProtUniProtAccP91082
UniProt_GCRPUniProtAccP91082
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:23WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classegl
Reference_alleleWBVar00089528
Allele (31)
Legacy_informationn481 : variable bloating Type A many animals form bag-of-worms (60%); abnormal vulva. ES2 adult. NA1.
See also e1952, n481
[C.elegansII] n481 : variable bloating, insensitive to serotonin and imipramine; 60% adults form bag-of-worms; abnormal vulva; suppressor of Tra-3. ES2 adult. ME3. OA1: e1952 (pka egl-48, HME1/2, stronger suppressor of Tra-3). [Trent et al. 1983; Hodgkin 1986; CB; MT]
StrainWBStrain00026509
WBStrain00026781
WBStrain00026856
WBStrain00004534
WBStrain00004636
RNASeq_FPKM (74)
GO_annotation (15)
Ortholog (27)
Structured_descriptionConcise_descriptionegl-26 encodes a protein that contains an H-box and an NC domain that is a member of the LRAT (lecithin retinol acyltransferase) subfamily of the NlpC/P60 superfamily of enzymes; egl-26 activity is required for fertility, egg laying, and vulval development, specifically the connection of the uterus to the vulva mediated by proper morphogenesis of vulF, the most dorsal vulval cell; EGL-26 is an apical membrane protein that is expressed in many cells, including vulF, and appears to be expressed near the vulva and uterus only during the L4 larval stage; EGL-26 membrane localization is necessary for its function.Paper_evidenceWBPaper00000635
WBPaper00005103
WBPaper00030762
Curator_confirmedWBPerson48
WBPerson1843
Date_last_updated07 Aug 2007 00:00:00
Automated_descriptionPredicted to enable acyltransferase activity. Involved in several processes, including egg-laying behavior; positive regulation of vulval development; and vulval development. Located in cytoplasmic side of apical plasma membrane. Expressed in several structures, including buccal cavity; excretory canal; hermaphrodite gonad; rectum; and vulval cell.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSC23H3.1a
C23H3.1b
Corresponding_transcriptC23H3.1a.1
C23H3.1b.1
Other_sequenceCR12698
CJC02584_1
CGC00868_1
CRC04517_1
Associated_featureWBsf654854
WBsf717611
WBsf717612
WBsf986311
WBsf986312
Experimental_infoRNAi_result (12)
Expr_pattern (11)
Drives_constructWBCnstr00000797
WBCnstr00006433
WBCnstr00010463
WBCnstr00011411
WBCnstr00019607
WBCnstr00022871
WBCnstr00037038
Construct_productWBCnstr00006433
WBCnstr00010463
WBCnstr00037038
Microarray_results (19)
Expression_cluster (102)
Interaction (62)
Map_infoMapIIPosition-16.2721Error0.158173
PositivePositive_cloneC23H3Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_data2_point797
2632
7078
7112
Multi_point743
1060
1674
3907
4244
Pos_neg_data4724
Reference (25)
RemarkSequence connection from [Hanna-Rose W, Han M]
cog-4 added as an other name. krb 04/03/02
MethodGene