WormBase Tree Display for Gene: WBGene00001169

WBGene00001169 SMap: S_parent: Sequence: CHROMOSOME_X
  Identity: Version: 2
    Name: CGC_name: eef-1A.2 Person_evidence: WBPerson1787
            WBPerson10190
      Sequence_name: R03G5.1
      Molecular_name: R03G5.1
        R03G5.1.1
        CE01270
        R03G5.1.2
        R03G5.1.3
      Other_name: eln-2
        eft-4
        C54D2.a Curator_confirmed: WBPerson1983
          Remark: Old cosmid naming mapped via unique overlapping PCR_product on CDSs
        R03G5.a Curator_confirmed: WBPerson1983
          Remark: Old cosmid naming mapped via unique overlapping PCR_product on CDSs
        R03G5.b Curator_confirmed: WBPerson1983
          Remark: Old cosmid naming mapped via unique overlapping PCR_product on CDSs
        CELE_R03G5.1 Accession_evidence: NDB BX284606
      Public_name: eef-1A.2
    DB_info: Database: AceView gene XI443
        WormQTL gene WBGene00001169
        WormFlux gene WBGene00001169
        NDB locus_tag CELE_R03G5.1
        NCBI gene 181044
        RefSeq protein NM_076922.5
        SwissProt UniProtAcc P53013
        UniProt_GCRP UniProtAcc P53013
        OMIM gene 602959
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:23 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 03 Aug 2010 09:32:43 WBPerson2970 Name_change: CGC_name: eef-1A-2
                Other_name: eft-4
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: eef
    Allele (48)
    Legacy_information: [C.elegansII] NMK. Encodes EF1 alpha protein, aa sequence identical to eft-3. [FK]
    RNASeq_FPKM (74)
    GO_annotation: 00108369
      00108370
      00108371
      00108372
    Ortholog (50)
    Paralog (17)
    Structured_description: Concise_description: eef-1A.2 encodes a translation elongation factor 1-alpha homolog that is required for embryonic viability, fertility, and a normal postembryonic growth rate; eef-1A.2 encodes at least one alternatively spliced coding sequence identical to that of eef-1A.1. Paper_evidence: WBPaper00004313
            WBPaper00004540
            WBPaper00005654
          Curator_confirmed: WBPerson48
            WBPerson1843
            WBPerson567
          Date_last_updated: 03 Dec 2014 00:00:00
      Automated_description: Predicted to enable GTP binding activity; GTPase activity; and translation elongation factor activity. Predicted to be involved in translational elongation. Human ortholog(s) of this gene implicated in Alzheimer's disease; autosomal dominant intellectual developmental disorder 38; developmental and epileptic encephalopathy 33; and ovarian cancer. Is an ortholog of human EEF1A1 (eukaryotic translation elongation factor 1 alpha 1); EEF1A1P5 (eukaryotic translation elongation factor 1 alpha 1 pseudogene 5); and EEF1A2 (eukaryotic translation elongation factor 1 alpha 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:10652 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:3192)
      DOID:0070068 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:3192)
      DOID:0080463 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:3192)
      DOID:2394 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:3192)
  Molecular_info: Corresponding_CDS: R03G5.1
    Corresponding_CDS_history: R03G5.1b:wp272
      R03G5.1c:wp272
      R03G5.1d:wp162
      R03G5.1d:wp272
    Corresponding_transcript: R03G5.1.1
      R03G5.1.2
      R03G5.1.3
    Other_sequence (769)
    Associated_feature (21)
  Experimental_info: RNAi_result (30)
    Expr_pattern: Expr1030746
      Expr1154893
      Expr2011178
      Expr2029414
    Drives_construct (11)
    Construct_product: WBCnstr00037980
    Microarray_results (34)
    Expression_cluster (226)
    Interaction: WBInteraction000048917
      WBInteraction000103009
      WBInteraction000103636
      WBInteraction000104570
      WBInteraction000105142
      WBInteraction000105214
      WBInteraction000105222
      WBInteraction000105259
      WBInteraction000106971
      WBInteraction000110110
      WBInteraction000110264
      WBInteraction000113267
      WBInteraction000113538
      WBInteraction000113701
      WBInteraction000113777
      WBInteraction000115155
      WBInteraction000115160
      WBInteraction000115161
      WBInteraction000115162
      WBInteraction000116029
      WBInteraction000118992
      WBInteraction000119099
      WBInteraction000119408
      WBInteraction000119666
      WBInteraction000120846
      WBInteraction000121602
      WBInteraction000124217
      WBInteraction000124796
      WBInteraction000125158
      WBInteraction000125685
      WBInteraction000125814
      WBInteraction000127142
      WBInteraction000127181
      WBInteraction000128006
      WBInteraction000128007
      WBInteraction000128008
      WBInteraction000128009
      WBInteraction000128010
      WBInteraction000128011
      WBInteraction000128012
      WBInteraction000128013
      WBInteraction000128014
      WBInteraction000128015
      WBInteraction000128016
      WBInteraction000128017
      WBInteraction000128018
      WBInteraction000128019
      WBInteraction000128020
      WBInteraction000128021
      WBInteraction000128022
      WBInteraction000128023
      WBInteraction000128024
      WBInteraction000128025
      WBInteraction000128026
      WBInteraction000128027
      WBInteraction000128984
      WBInteraction000129039
      WBInteraction000129051
      WBInteraction000129073
      WBInteraction000129081
      WBInteraction000129086
      WBInteraction000129097
      WBInteraction000129103
      WBInteraction000129118
      WBInteraction000129129
      WBInteraction000129135
      WBInteraction000129144
      WBInteraction000129164
      WBInteraction000129183
      WBInteraction000129190
      WBInteraction000129204
      WBInteraction000129218
      WBInteraction000129230
      WBInteraction000129254
      WBInteraction000129298
      WBInteraction000129314
      WBInteraction000129330
      WBInteraction000129352
      WBInteraction000129374
      WBInteraction000129389
      WBInteraction000129418
      WBInteraction000129447
      WBInteraction000129493
      WBInteraction000129543
      WBInteraction000129618
      WBInteraction000129643
      WBInteraction000129673
      WBInteraction000129691
      WBInteraction000129720
      WBInteraction000129755
      WBInteraction000129777
      WBInteraction000129849
      WBInteraction000129884
      WBInteraction000129904
      WBInteraction000129942
      WBInteraction000129981
      WBInteraction000130021
      WBInteraction000130069
      WBInteraction000130613
      WBInteraction000132077
      WBInteraction000132989
      WBInteraction000133164
      WBInteraction000133300
      WBInteraction000133734
      WBInteraction000135747
      WBInteraction000136171
      WBInteraction000136671
      WBInteraction000136724
      WBInteraction000140482
      WBInteraction000141747
      WBInteraction000141762
      WBInteraction000141765
      WBInteraction000141767
      WBInteraction000144911
      WBInteraction000147837
      WBInteraction000149956
      WBInteraction000151946
      WBInteraction000152773
      WBInteraction000153685
      WBInteraction000158014
      WBInteraction000158015
      WBInteraction000158016
      WBInteraction000158380
      WBInteraction000158388
      WBInteraction000158941
      WBInteraction000159136
      WBInteraction000159219
      WBInteraction000159389
      WBInteraction000162841
      WBInteraction000166677
      WBInteraction000172481
      WBInteraction000173945
      WBInteraction000177820
      WBInteraction000185208
      WBInteraction000185571
      WBInteraction000187068
      WBInteraction000189123
      WBInteraction000193261
      WBInteraction000201250
      WBInteraction000202147
      WBInteraction000205487
      WBInteraction000208828
      WBInteraction000211203
      WBInteraction000213169
      WBInteraction000213774
      WBInteraction000219574
      WBInteraction000221303
      WBInteraction000221309
      WBInteraction000225928
      WBInteraction000228037
      WBInteraction000237863
      WBInteraction000240376
      WBInteraction000240406
      WBInteraction000241427
      WBInteraction000243403
      WBInteraction000243435
      WBInteraction000243436
      WBInteraction000243437
      WBInteraction000243438
      WBInteraction000243439
      WBInteraction000243440
      WBInteraction000243441
      WBInteraction000243442
      WBInteraction000243443
      WBInteraction000243444
      WBInteraction000243458
      WBInteraction000243462
      WBInteraction000243464
      WBInteraction000243467
      WBInteraction000243478
      WBInteraction000243486
      WBInteraction000243491
      WBInteraction000243501
      WBInteraction000243508
      WBInteraction000243510
      WBInteraction000243513
      WBInteraction000243538
      WBInteraction000243578
      WBInteraction000243799
      WBInteraction000243854
      WBInteraction000243912
      WBInteraction000243985
      WBInteraction000244061
      WBInteraction000249265
      WBInteraction000250208
      WBInteraction000252141
      WBInteraction000267974
      WBInteraction000268183
      WBInteraction000269339
      WBInteraction000274385
      WBInteraction000274640
      WBInteraction000275135
      WBInteraction000275302
      WBInteraction000276502
      WBInteraction000288363
      WBInteraction000289322
      WBInteraction000290152
      WBInteraction000295388
      WBInteraction000299577
      WBInteraction000309559
      WBInteraction000310244
      WBInteraction000315099
      WBInteraction000318863
      WBInteraction000324250
      WBInteraction000325630
      WBInteraction000329012
      WBInteraction000330211
      WBInteraction000331123
      WBInteraction000337025
      WBInteraction000339675
      WBInteraction000340269
      WBInteraction000340722
      WBInteraction000341281
      WBInteraction000343609
      WBInteraction000345628
      WBInteraction000348184
      WBInteraction000349478
      WBInteraction000351691
      WBInteraction000357346
      WBInteraction000364255
      WBInteraction000364308
      WBInteraction000368085
      WBInteraction000373037
      WBInteraction000373825
      WBInteraction000375526
      WBInteraction000377379
      WBInteraction000379921
      WBInteraction000381795
      WBInteraction000385217
      WBInteraction000386516
      WBInteraction000387416
      WBInteraction000391418
      WBInteraction000406353
      WBInteraction000407395
      WBInteraction000416523
      WBInteraction000419645
      WBInteraction000420381
      WBInteraction000420571
      WBInteraction000425375
      WBInteraction000427553
      WBInteraction000432822
      WBInteraction000432825
      WBInteraction000434167
      WBInteraction000440905
      WBInteraction000447807
      WBInteraction000450965
      WBInteraction000454002
      WBInteraction000455482
      WBInteraction000458845
      WBInteraction000461260
      WBInteraction000461311
      WBInteraction000463320
      WBInteraction000463458
      WBInteraction000463628
      WBInteraction000464290
      WBInteraction000465021
      WBInteraction000465178
      WBInteraction000465701
      WBInteraction000466021
      WBInteraction000466789
      WBInteraction000467866
      WBInteraction000469440
      WBInteraction000470013
      WBInteraction000470790
      WBInteraction000471159
      WBInteraction000471234
      WBInteraction000472180
      WBInteraction000472244
      WBInteraction000472246
      WBInteraction000474167
      WBInteraction000474275
      WBInteraction000474276
      WBInteraction000474277
      WBInteraction000475295
      WBInteraction000504928
      WBInteraction000519533
      WBInteraction000519534
      WBInteraction000519535
      WBInteraction000519536
      WBInteraction000519537
      WBInteraction000519538
      WBInteraction000519539
      WBInteraction000519540
      WBInteraction000519541
      WBInteraction000519616
      WBInteraction000519622
      WBInteraction000519629
      WBInteraction000519630
      WBInteraction000549822
      WBInteraction000549826
      WBInteraction000551157
      WBInteraction000554097
      WBInteraction000558784
      WBInteraction000561711
      WBInteraction000562024
      WBInteraction000562342
      WBInteraction000562454
      WBInteraction000565077
      WBInteraction000565106
      WBInteraction000566340
      WBInteraction000566619
      WBInteraction000567463
      WBInteraction000571949
      WBInteraction000572484
      WBInteraction000572735
      WBInteraction000579973
      WBInteraction000584573
  Map_info: Map: X Position: -1.12456
    Positive: Positive_clone: R03G5 Inferred_automatically: From sequence, transcript, pseudogene data
        YO#EFG5
    Pseudo_map_position
  Reference: WBPaper00024924
    WBPaper00025088
    WBPaper00027281
    WBPaper00037777
    WBPaper00038491
    WBPaper00049828
    WBPaper00055090
    WBPaper00065634
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene