WormBase Tree Display for Gene: WBGene00001122
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| WBGene00001122 | SMap | S_parent | Sequence | F46F6 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | dyf-6 | Person_evidence | WBPerson252 | |||||
| Sequence_name | F46F6.4 | ||||||||
| Molecular_name (13) | |||||||||
| Other_name | CELE_F46F6.4 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | dyf-6 | ||||||||
| DB_info | Database | WormQTL | gene | WBGene00001122 | |||||
| WormFlux | gene | WBGene00001122 | |||||||
| NDB | locus_tag | CELE_F46F6.4 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00001122|UniProtKB=Q0G838 | |||||||
| family | PTHR13376 | ||||||||
| NCBI | gene | 3565899 | |||||||
| RefSeq | protein | NM_001083298.2 | |||||||
| NM_001392834.1 | |||||||||
| NM_001083299.3 | |||||||||
| NM_001083301.4 | |||||||||
| SwissProt | UniProtAcc | Q0G838 | |||||||
| TREEFAM | TREEFAM_ID | TF314221 | |||||||
| UniProt_GCRP | UniProtAcc | Q0G838 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:23 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Name_change | CGC_name | dyf-6 | |||||||
| 2 | 15 Aug 2006 16:37:11 | WBPerson1983 | Event | Acquires_merge | WBGene00009794 | ||||
| Acquires_merge | WBGene00009795 | ||||||||
| WBGene00009794 | |||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | dyf | ||||||||
| Allele (113) | |||||||||
| Legacy_information | [Herman RK] Defective in dye (FITC or DiO) filling of amphid and phasmid neurons. Chemotaxis defective. ME3(m175), ME4(mn346) | ||||||||
| [C.elegansII] m175 : defective in dye (FITC or DiO) filling of amphid and phasmid neurons. Chemotaxis defective. ME3(m175), ME4(mn346) OA1: mn346mut. [Starich et al. 1995] | |||||||||
| Complementation_data | [Herman RK] dyf-6(m175) complements dyf-7(m537), dyf-12(sa127), daf-12(m20) and vab-3(e648) with respect to dye filling. dyf-6(mn346) complements dyf-12(sa122) and vab-3(e648) with respect to dye filling. | ||||||||
| Strain | WBStrain00034381 | ||||||||
| WBStrain00034417 | |||||||||
| WBStrain00036858 | |||||||||
| WBStrain00036887 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (18) | |||||||||
| Ortholog (40) | |||||||||
| Structured_description | Concise_description | dyf-6 encodes several proteins that, while novel, contain orthologs in Drosophila and mammals; during development, dyf-6 activity is essential for establishing the normal dendritic length of the amphid and phasmid chemosensory neurons; a DYF-6::GFP reporter is expressed in amphid and phasmid neurons where it: 1) localizes to dendritic bodies and endings as well as to cell bodies, and 2) appears to undergo intraflagellar transport (IFT); DYF-6::GFP is also seen in hypodermal cells and in additional neurons, including inner labial neurons and a lateral neuron in the vicinity of PDE; genetic mosaic analyses indicate that dyf-6 functions autonomously at the level of the amphid dendritic bundle to regulate proper dendritic morphology. | Paper_evidence | WBPaper00002087 | |||||
| WBPaper00027360 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 23 Feb 2007 00:00:00 | ||||||||
| Automated_description | Involved in intraciliary transport and non-motile cilium assembly. Located in dendrite and neuronal cell body. Expressed in ciliated neurons and hypodermis. Is an ortholog of human IFT46 (intraflagellar transport 46). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F46F6.4a | |||||||
| F46F6.4b | |||||||||
| F46F6.4c | |||||||||
| F46F6.4d | |||||||||
| Corresponding_CDS_history | F46F6.4:wp163 | ||||||||
| Corresponding_transcript | F46F6.4a.1 | ||||||||
| F46F6.4b.1 | |||||||||
| F46F6.4c.1 | |||||||||
| F46F6.4c.2 | |||||||||
| F46F6.4d.1 | |||||||||
| Other_sequence | CR03480 | ||||||||
| CRC02533_1 | |||||||||
| Oden_isotig25770 | |||||||||
| JI479891.1 | |||||||||
| Associated_feature (14) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00015120 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00047566 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00047565 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr4523 | ||||||||
| Expr1017659 | |||||||||
| Expr1030717 | |||||||||
| Expr1151403 | |||||||||
| Expr2011136 | |||||||||
| Expr2029372 | |||||||||
| Drives_construct | WBCnstr00012076 | ||||||||
| WBCnstr00016048 | |||||||||
| WBCnstr00037074 | |||||||||
| Construct_product | WBCnstr00012076 | ||||||||
| WBCnstr00037074 | |||||||||
| Microarray_results (33) | |||||||||
| Expression_cluster (125) | |||||||||
| Interaction (32) | |||||||||
| Map_info | Map | X | Position | 2.16901 | Error | 0.003805 | |||
| Positive | Positive_clone | F46F6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 3090 | |||||||
| 3091 | |||||||||
| Pos_neg_data | 8324 | ||||||||
| 8329 | |||||||||
| 8325 | |||||||||
| Reference (15) | |||||||||
| Method | Gene |
