e184sd : strong dumpy; e184/+ is medium dumpy. ES3 (all stages). ME2. NA7. (e458 e1165icr e225 (pka dpy-16 : recessive medium dumpy)).
See dpy-13.
See also e225
[C.elegansII] e184sd : strong dumpy; e184/+ is medium dumpy. ES3 (all stages). ME2. NA13: e458, e1165icr, e225 (pka dpy-16 : recessive medium dumpy), e458, m399::Tc1, e1165, etc. Cloned: encodes 302 aa collagen; dpy-13 family includes col-2, col-34, sqt-3; e184 is in-frame deletion, e458 is 673 bp deletion, null, strong dumpy.Expressed at each larval stage, 4 to 2.5 hours pre-lethargus. [Brenner 1974; von Mende et al. 1988; CH; IA]
dpy-13 encodes a member of the collagen superfamily containing 20 copies of the collagen triple helix repeat; transcipt levels oscillate, peaking once during each larval stage.
Predicted to be a structural constituent of cuticle. Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle. Located in collagen and cuticulin-based cuticle extracellular matrix.