WormBase Tree Display for Gene: WBGene00001029
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| WBGene00001029 | SMap | S_parent | Sequence | F38A5 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | dnj-11 | Person_evidence | WBPerson625 | |||||
| Sequence_name | F38A5.13 | ||||||||
| Molecular_name | F38A5.13 | ||||||||
| F38A5.13.1 | |||||||||
| CE10050 | |||||||||
| Other_name | CELE_F38A5.13 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | dnj-11 | ||||||||
| DB_info | Database | AceView | gene | 4H351 | |||||
| WormQTL | gene | WBGene00001029 | |||||||
| WormFlux | gene | WBGene00001029 | |||||||
| NDB | locus_tag | CELE_F38A5.13 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00001029|UniProtKB=Q94216 | |||||||
| family | PTHR43999 | ||||||||
| NCBI | gene | 177419 | |||||||
| RefSeq | protein | NM_068605.7 | |||||||
| TREEFAM | TREEFAM_ID | TF105834 | |||||||
| TrEMBL | UniProtAcc | Q94216 | |||||||
| UniProt_GCRP | UniProtAcc | Q94216 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:22 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | dnj | ||||||||
| Allele (20) | |||||||||
| Strain | WBStrain00002980 | ||||||||
| WBStrain00001612 | |||||||||
| WBStrain00036761 | |||||||||
| WBStrain00055557 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (11) | |||||||||
| Ortholog (39) | |||||||||
| Paralog (11) | |||||||||
| Structured_description | Concise_description | dnj-11 encodes a protein containing DnaJ and Myb domains that is orthologousto the mammalian ZRF1/MIDA1/MPP11/DNAJC2 family of ribosome-associated molecular chaperones; in C. elegans, dnj-11 functions to regulate asymmetriccell division and mitotic spindle orientation in the NSM neuroblast andsubsequently the apoptotic death of the NSM sister cell; in regulatingNSM sister cell death, DNJ-11 functions together with CES-2 to negativelyregulate ces-1 transcription in the NSM lineage; in addition to its rolein NSM lineage cell fate, dnj-11 activity is also required generally for embryonic development, growth, reproduction, body morphology, and vulval development; a DNJ-11::GFP reporter fusion is expressed in nearly all somatic cells of embryos, larvae, and adults, and localizes to the cytosol; as dnj-11 mutations are maternally rescuable, dnj-11 is also likely expressed in the germline. | Paper_evidence | WBPaper00031670 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 15 Dec 2008 00:00:00 | ||||||||
| Automated_description | Predicted to enable Hsp70 protein binding activity and ribosome binding activity. Predicted to be involved in 'de novo' cotranslational protein folding. Located in cytosol. Expressed in several structures, including head; muscle cell; neurons; and tail. Is an ortholog of human DNAJC2 (DnaJ heat shock protein family (Hsp40) member C2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F38A5.13 | |||||||
| Corresponding_transcript | F38A5.13.1 | ||||||||
| Other_sequence (50) | |||||||||
| Associated_feature | WBsf646024 | ||||||||
| WBsf646025 | |||||||||
| WBsf660236 | |||||||||
| WBsf660237 | |||||||||
| WBsf978439 | |||||||||
| WBsf228429 | |||||||||
| Transcription_factor | WBTranscriptionFactor001004 | ||||||||
| Experimental_info | RNAi_result | WBRNAi00046670 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00000257 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00031941 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00077838 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00106326 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00014527 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00094998 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00077536 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00076391 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00007734 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Chronogram1546 | ||||||||
| Expr5988 | |||||||||
| Expr5989 | |||||||||
| Expr7546 | |||||||||
| Expr8063 | |||||||||
| Expr1017470 | |||||||||
| Expr1030641 | |||||||||
| Expr1150545 | |||||||||
| Expr2010985 | |||||||||
| Expr2029223 | |||||||||
| Drives_construct | WBCnstr00002451 | ||||||||
| WBCnstr00004346 | |||||||||
| WBCnstr00012691 | |||||||||
| WBCnstr00013087 | |||||||||
| WBCnstr00037132 | |||||||||
| Construct_product | WBCnstr00037132 | ||||||||
| Antibody | WBAntibody00002965 | ||||||||
| Microarray_results (22) | |||||||||
| Expression_cluster (186) | |||||||||
| Interaction (202) | |||||||||
| Map_info | Map | IV | Position | 3.20984 | Error | 0.000436 | |||
| Positive | Positive_clone | F38A5 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00027979 | ||||||||
| WBPaper00031670 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00043980 | |||||||||
| WBPaper00044432 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00062388 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
