WormBase Tree Display for Gene: WBGene00000917
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| WBGene00000917 | SMap | S_parent | Sequence | Y48G1A | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | daf-25 | Person_evidence | WBPerson521 | |||||
| Sequence_name | Y48G1A.3 | ||||||||
| Molecular_name | Y48G1A.3 | ||||||||
| Y48G1A.3.1 | |||||||||
| CE26999 | |||||||||
| Other_name | chb-3 | Paper_evidence | WBPaper00037842 | ||||||
| Y48G1A.f | Curator_confirmed | WBPerson1983 | |||||||
| Remark | Old cosmid naming mapped via unique overlapping PCR_product on CDSs | ||||||||
| CELE_Y48G1A.3 | Accession_evidence | NDB | BX284601 | ||||||
| Public_name | daf-25 | ||||||||
| DB_info | Database | AceView | gene | 1A809 | |||||
| WormFlux | gene | WBGene00000917 | |||||||
| NDB | locus_tag | CELE_Y48G1A.3 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00000917|UniProtKB=Q9N3Q8 | |||||||
| family | PTHR24150 | ||||||||
| NCBI | gene | 171623 | |||||||
| RefSeq | protein | NM_058318.5 | |||||||
| SwissProt | UniProtAcc | Q9N3Q8 | |||||||
| TREEFAM | TREEFAM_ID | TF351374 | |||||||
| UniProt_GCRP | UniProtAcc | Q9N3Q8 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:22 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 07 Dec 2010 15:23:47 | WBPerson2970 | Event | Acquires_merge | WBGene00021659 | ||||
| Name_change | Sequence_name | Y48G1A.3 | |||||||
| Other_name | chb-3 | ||||||||
| Acquires_merge | WBGene00021659 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | daf | ||||||||
| Allele (110) | |||||||||
| Legacy_information | [C.elegansII] m362ts, mat : constitutive formation of dauer larvae at 25C, poor dauer recovery at 15C, adults Egl.ES3(L3). OA3. [DR] | ||||||||
| Strain | WBStrain00006405 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (22) | |||||||||
| Contained_in_operon | CEOP1968 | ||||||||
| Ortholog (32) | |||||||||
| Structured_description | Concise_description | daf-25 encodes an MYND domain-containing protein that is the C. elegans ortholog of mammalian Ankmy2; DAF-25 activity is required for proper regulation of dauer formation and recovery, as well as for chemotaxis, response to osmotic stress, and egg-laying; DAF-25 specifically regulates localization of the membrane-bound DAF-11 guanylyl cyclase to cilia and the daf-25 dauer phenotype is rescued by 8-bromo-cGMP, suggesting that DAF-25 functions to regulate a cGMP-mediated signaling pathway that controls these behaviors; a DAF-25::GFP reporter fusion is expressed in chemosensory neurons and localizes to cilia. | Paper_evidence | WBPaper00037836 | |||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson1843 | |||||||||
| Date_last_updated | 01 Apr 2011 00:00:00 | ||||||||
| Automated_description | Predicted to enable metal ion binding activity. Involved in several processes, including dauer exit; positive regulation of cGMP-mediated signaling; and protein localization to cell periphery. Located in non-motile cilium. Expressed in intestine and sensory neurons. Is an ortholog of human ANKMY2 (ankyrin repeat and MYND domain containing 2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | Y48G1A.3 | |||||||
| Corresponding_transcript | Y48G1A.3.1 | ||||||||
| Other_sequence (24) | |||||||||
| Associated_feature | WBsf982469 | ||||||||
| WBsf982470 | |||||||||
| WBsf982471 | |||||||||
| WBsf982472 | |||||||||
| WBsf1009067 | |||||||||
| WBsf1009068 | |||||||||
| WBsf1009069 | |||||||||
| WBsf1009070 | |||||||||
| WBsf1009071 | |||||||||
| WBsf217121 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00116549 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00001096 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00056935 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00094976 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00037267 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr9169 | ||||||||
| Expr9171 | |||||||||
| Expr1030577 | |||||||||
| Expr1160381 | |||||||||
| Expr2010771 | |||||||||
| Expr2029008 | |||||||||
| Drives_construct | WBCnstr00007996 | ||||||||
| WBCnstr00013765 | |||||||||
| WBCnstr00013767 | |||||||||
| Construct_product | WBCnstr00007996 | ||||||||
| WBCnstr00007997 | |||||||||
| WBCnstr00007998 | |||||||||
| WBCnstr00007999 | |||||||||
| WBCnstr00008000 | |||||||||
| WBCnstr00008001 | |||||||||
| WBCnstr00008002 | |||||||||
| WBCnstr00013765 | |||||||||
| WBCnstr00013767 | |||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (91) | |||||||||
| Interaction (15) | |||||||||
| Map_info | Map | I | Position | -19.0733 | Error | 0.001946 | |||
| Positive | Positive_clone | Y48G1A | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (15) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
