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WormBase Tree Display for Gene: WBGene00000895

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Name Class

WBGene00000895SMapS_parentSequenceB0412
IdentityVersion1
NameCGC_namedac-1Person_evidenceWBPerson473
Sequence_nameB0412.1
Molecular_nameB0412.1a
B0412.1a.1
CE26848
B0412.1b
CE33550
B0412.1b.1
Other_nameski-1Person_evidenceWBPerson473
CELE_B0412.1Accession_evidenceNDBBX284603
Public_namedac-1
DB_infoDatabaseAceViewgene3B439
WormQTLgeneWBGene00000895
WormFluxgeneWBGene00000895
NDBlocus_tagCELE_B0412.1
PanthergeneCAEEL|WormBase=WBGene00000895|UniProtKB=H2KY91
familyPTHR12577
NCBIgene175238
RefSeqproteinNM_001025959.5
NM_001025958.4
SwissProtUniProtAccH2KY91
TREEFAMTREEFAM_IDTF316697
UniProt_GCRPUniProtAccH2KY91
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:21WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classdac
Allele (159)
StrainWBStrain00001324
WBStrain00001325
WBStrain00035649
WBStrain00035733
WBStrain00035736
RNASeq_FPKM (74)
GO_annotation00021457
00021458
00021459
00021460
00021461
00021462
00021463
00021464
00021465
OrthologWBGene00064873Caenorhabditis remaneiFrom_analysisOMA
TreeFam
Inparanoid_8
WormBase-Compara
WBGene00042367Caenorhabditis briggsaeFrom_analysisHillier-set
OrthoMCL
OMA
Inparanoid_8
WormBase-Compara
WBGene00141880Caenorhabditis brenneriFrom_analysisOMA
TreeFam
Inparanoid_8
WormBase-Compara
WBGene00222057Brugia malayiFrom_analysisWormBase-Compara
CBOVI.g4872Caenorhabditis bovisFrom_analysisWormBase-Compara
CSP21.g715Caenorhabditis parvicaudaFrom_analysisWormBase-Compara
CSP26.g92Caenorhabditis zanzibariFrom_analysisWormBase-Compara
CSP28.g18572Caenorhabditis panamensisFrom_analysisWormBase-Compara
CSP29.g22595Caenorhabditis beceiFrom_analysisWormBase-Compara
CSP31.g24067Caenorhabditis uteleiaFrom_analysisWormBase-Compara
CSP32.g11187Caenorhabditis sulstoniFrom_analysisWormBase-Compara
CSP38.g5733Caenorhabditis quiockensisFrom_analysisWormBase-Compara
CSP39.g21499Caenorhabditis waitukubuliFrom_analysisWormBase-Compara
CSP40.g6823Caenorhabditis tribulationisFrom_analysisWormBase-Compara
Cang_2012_03_13_00005.g416Caenorhabditis angariaFrom_analysisWormBase-Compara
Cni-dac-1Caenorhabditis nigoniFrom_analysisWormBase-Compara
Csp5_scaffold_01681.g22490Caenorhabditis sinicaFrom_analysisWormBase-Compara
FL83_22957Caenorhabditis latensFrom_analysisWormBase-Compara
GCK72_011866Caenorhabditis remaneiFrom_analysisWormBase-Compara
OTIPU.nOt.2.0.1.g03717Oscheius tipulaeFrom_analysisWormBase-Compara
Pan_g5803Panagrellus redivivusFrom_analysisWormBase-Compara
Sp34_30331100Caenorhabditis inopinataFrom_analysisWormBase-Compara
chrIII_pilon.g6820Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00111400Pristionchus pacificusFrom_analysisWormBase-Compara
WBGene00262311Strongyloides rattiFrom_analysisWormBase-Compara
WBGene00302697Trichuris murisFrom_analysisWormBase-Compara
FB:FBgn0005677Drosophila melanogasterFrom_analysisEnsEMBL-Compara
OrthoFinder
OrthoInspector
Panther
ZFIN:ZDB-GENE-020402-3Danio rerioFrom_analysisEnsEMBL-Compara
Inparanoid
OrthoFinder
OrthoInspector
Panther
ZFIN:ZDB-GENE-020402-4Danio rerioFrom_analysisEnsEMBL-Compara
Inparanoid
OrthoFinder
OrthoInspector
Panther
ZFIN:ZDB-GENE-020402-5Danio rerioFrom_analysisEnsEMBL-Compara
Inparanoid
OrthoFinder
OrthoInspector
Panther
ZFIN:ZDB-GENE-070427-2Danio rerioFrom_analysisEnsEMBL-Compara
Inparanoid
OrthoFinder
OrthoInspector
Panther
HGNC:2663Homo sapiensFrom_analysisEnsEMBL-Compara
OrthoFinder
OrthoInspector
Panther
PhylomeDB
HGNC:16814Homo sapiensFrom_analysisOrthoFinder
OrthoInspector
Panther
MGI:1277991Mus musculusFrom_analysisEnsEMBL-Compara
OrthoFinder
OrthoInspector
Panther
SonicParanoid
MGI:1890446Mus musculusFrom_analysisOrthoFinder
OrthoInspector
Panther
SonicParanoid
RGD:1592073Rattus norvegicusFrom_analysisEnsEMBL-Compara
OrthoFinder
OrthoInspector
Panther
Structured_descriptionConcise_descriptiondac-1 encodes the C. elegans ortholog of Dachshund, a transcriptional regulator first described in Drosophila that is a member of the SKI/SNO/DAC family of proteins; dac-1 is expressed at higher levels in the AFD thermosensory neurons as compared to the AWB olfactory neurons and likely plays a role in thermosensory behavior as on thermal gradients dac-1 mutants fail to suppress cryophilic drive but continue to track isotherms at the cultivation temperature; a DAC-1::GFP fusion protein is nuclear and expressed strongly in the AFD thermosensory neurons, but weakly in the AWC, ASE, and ASK chemosensory neurons; expression is also seen in alae and additional, unidentified tail cells; dac-1 expression in AFD is positively regulated by the TTX-1 OTX-like homeodomain protein.Paper_evidenceWBPaper00024671
Curator_confirmedWBPerson1843
Date_last_updated21 May 2007 00:00:00
Automated_descriptionPredicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in thermotaxis. Located in nucleus. Expressed in amphid neurons; cuticular ala; and tail. Is an ortholog of human DACH1 (dachshund family transcription factor 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSB0412.1a
B0412.1b
Corresponding_CDS_historyB0412.1b:wp120
B0412.1b:wp123
Corresponding_transcriptB0412.1a.1
B0412.1b.1
Other_sequenceDviv_isotig11489
SSC00720_1
Dviv_isotig11488
SS02097
Associated_featureWBsf658584
WBsf978943
WBsf224400
Transcription_factorWBTranscriptionFactor000635
Experimental_infoRNAi_resultWBRNAi00028128Inferred_automaticallyRNAi_primary
WBRNAi00009756Inferred_automaticallyRNAi_primary
WBRNAi00006647Inferred_automaticallyRNAi_primary
WBRNAi00110961Inferred_automaticallyRNAi_primary
WBRNAi00039031Inferred_automaticallyRNAi_primary
Expr_patternChronogram2070
Expr3130
Expr5066
Expr7403
Expr1015167
Expr1143193
Expr1200045
Expr2010758
Expr2028995
Drives_constructWBCnstr00002217
WBCnstr00002218
WBCnstr00011158
WBCnstr00012546
WBCnstr00037214
Construct_productWBCnstr00011158
WBCnstr00016702
WBCnstr00037214
Microarray_results (24)
Expression_cluster (120)
Interaction (95)
WBProcessWBbiopr:00000010
Map_infoMapIIIPosition-25.7793Error0.003862
PositivePositive_cloneB0412Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4251
Pseudo_map_position
ReferenceWBPaper00010874
WBPaper00024524
WBPaper00024671
WBPaper00026952
WBPaper00027309
WBPaper00033137
WBPaper00034843
WBPaper00038491
WBPaper00055090
WBPaper00065158
Remarkski-1 became an other-name of dac-1 as this locus encodes the C. elegans ortholog of Dachshund, rather than of the related protein SKIPerson_evidenceWBPerson473
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene