WormBase Tree Display for Gene: WBGene00000882

WBGene00000882 SMap: S_parent: Sequence: F42G9
  Identity: Version: 2
    Name: CGC_name: cyn-6 Person_evidence: WBPerson466
      Sequence_name: F42G9.2
      Molecular_name: F42G9.2
        F42G9.2.1
        CE01301
      Other_name: cyp-6 Person_evidence: WBPerson466
        CELE_F42G9.2 Accession_evidence: NDB BX284603
      Public_name: cyn-6
    DB_info: Database (13)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:21 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 20 Sep 2004 16:20:03 WBPerson1971 Name_change: CGC_name: cyp-6 -> cyn-6
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: cyn
    Allele (14)
    Legacy_information: [C.elegansII] NMK. Cyclophilin family. Signal peptide. Cosmid C51B6. [TP]
    RNASeq_FPKM (74)
    GO_annotation (11)
    Ortholog: WBGene00064854 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00035556 Caenorhabditis briggsae From_analysis: OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00149243 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00119937 Caenorhabditis japonica From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00108033 Pristionchus pacificus From_analysis: Inparanoid_8
      WBGene00232565 Brugia malayi From_analysis: WormBase-Compara
      CSP26.g5180 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g10312 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g22693 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g22988 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g5816 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g14574 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP38.g9429 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g8180 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g6894 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cnig_chr_III.g8369 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold630.g16683 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_01691.g22563 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_19073 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_011886 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g04370 Oscheius tipulae From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g14341 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g15599 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_30329300 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrIII_pilon.g6813 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00238679 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00103512 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00304422 Pristionchus pacificus From_analysis: WormBase-Compara
      SGD:S000002712 Saccharomyces cerevisiae From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoInspector
            Panther
            SonicParanoid
      SGD:S000001099 Saccharomyces cerevisiae From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoInspector
            Panther
            SonicParanoid
      FB:FBgn0034753 Drosophila melanogaster From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-040426-1955 Danio rerio From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      HGNC:9255 Homo sapiens From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      MGI:97750 Mus musculus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      RGD:620312 Rattus norvegicus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
    Paralog (18)
    Structured_description: Concise_description: cyn-6 encodes a cyclophilin most similar to human secreted cyclophilin type B isoforms that is functional when expressed in E. coli; it is expressed in the intestine. Paper_evidence: WBPaper00002472
            WBPaper00005482
            WBPaper00026884
          Curator_confirmed: WBPerson48
            WBPerson1843
          Date_last_updated: 20 Mar 2007 00:00:00
      Automated_description: Predicted to enable cyclosporin A binding activity and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Expressed in intestine. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 9. Is an ortholog of human PPIB (peptidylprolyl isomerase B). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0110349 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:9255)
  Molecular_info: Corresponding_CDS: F42G9.2
    Corresponding_transcript: F42G9.2.1
    Other_sequence (76)
    Associated_feature: WBsf654939
      WBsf658581
  Experimental_info: RNAi_result: WBRNAi00076416 Inferred_automatically: RNAi_primary
      WBRNAi00027816 Inferred_automatically: RNAi_primary
      WBRNAi00014849 Inferred_automatically: RNAi_primary
      WBRNAi00006569 Inferred_automatically: RNAi_primary
      WBRNAi00047133 Inferred_automatically: RNAi_primary
      WBRNAi00022707 Inferred_automatically: RNAi_primary
      WBRNAi00090595 Inferred_automatically: RNAi_primary
      WBRNAi00022708 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1991
      Expr1024208
      Expr1030547
      Expr1151001
      Expr2010674
      Expr2028914
    Drives_construct: WBCnstr00010563
      WBCnstr00037224
    Construct_product: WBCnstr00010563
      WBCnstr00037224
    Microarray_results (19)
    Expression_cluster (222)
    SAGE_tag (15)
    Interaction (142)
  Map_info: Map: III Position: -26.1239 Error: 0.022372
    Positive: Positive_clone: C51B6 Author_evidence: Page AM
        F42G9 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (9)
  Remark: signal_peptide
    [Page AM] Initially identified by the sequencing project. Referred to as cypB homolog by Blast analysis. cDNA clone isolated
    PPIase or cyclophilin, EC 5.2.1.8
    This gene has been renamed with approval of the CGC (cyp-6->cyn-6) Person_evidence: WBPerson466
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene