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WormBase Tree Display for Gene: WBGene00000882

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Name Class

WBGene00000882SMapS_parentSequenceF42G9
IdentityVersion2
NameCGC_namecyn-6Person_evidenceWBPerson466
Sequence_nameF42G9.2
Molecular_nameF42G9.2
F42G9.2.1
CE01301
Other_namecyp-6Person_evidenceWBPerson466
CELE_F42G9.2Accession_evidenceNDBBX284603
Public_namecyn-6
DB_infoDatabaseAceViewgene3B391
WormQTLgeneWBGene00000882
WormFluxgeneWBGene00000882
NDBlocus_tagCELE_F42G9.2
PanthergeneCAEEL|WormBase=WBGene00000882|UniProtKB=P52014
familyPTHR11071
NCBIgene175231
RefSeqproteinNM_064856.7
KEGGKEGG_id5.2.1.8
NemaPathKEGG_id5.2.1.8
SwissProtUniProtAccP52014
TREEFAMTREEFAM_IDTF354259
UniProt_GCRPUniProtAccP52014
OMIMgene123841
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:21WBPerson1971EventImportedInitial conversion from geneace
220 Sep 2004 16:20:03WBPerson1971Name_changeCGC_namecyp-6 -> cyn-6
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcyn
Allele (14)
Legacy_information[C.elegansII] NMK. Cyclophilin family. Signal peptide. Cosmid C51B6. [TP]
RNASeq_FPKM (74)
GO_annotation (11)
Ortholog (35)
Paralog (18)
Structured_descriptionConcise_descriptioncyn-6 encodes a cyclophilin most similar to human secreted cyclophilin type B isoforms that is functional when expressed in E. coli; it is expressed in the intestine.Paper_evidenceWBPaper00002472
WBPaper00005482
WBPaper00026884
Curator_confirmedWBPerson48
WBPerson1843
Date_last_updated20 Mar 2007 00:00:00
Automated_descriptionPredicted to enable cyclosporin A binding activity and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Expressed in intestine. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 9. Is an ortholog of human PPIB (peptidylprolyl isomerase B).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0110349Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9255)
Molecular_infoCorresponding_CDSF42G9.2
Corresponding_transcriptF42G9.2.1
Other_sequencePT04104
AS01562
RS06060
Acan_isotig17815
FE920113.1
XI03787
CR00527
NB07237
Tcol_isotig12750
HS01081
MHC08498_1
TVC00084_1
XI00567
MI01232
Dviv_isotig10701
GPC03225_1
BU586459.1
CN477818.1
XI04046
MHC03950_1
ES740797.1
GR979168.1
MCC00825_1
TV00358
Acan_isotig06375
GRC03112_1
MC00225
CJC02284_1
CRC01947_1
GO252584.1
OOC02049_1
MH02081
MH02914
EX537831.1
PTC03567_1
MPC01511_1
NBC02918_1
TVC01248_1
TSC01680_1
ALC00189_1
GR367818.1
RS08408
GR11913
HC03877
JK315029.1
EX544231.1
MH01061
Dviv_isotig10700
Dviv_isotig10699
TMC01104_1
TS00144
RSC01443_1
TS02400
RS07233
Acan_isotig06374
HSC00971_1
MPC01526_1
XIC01537_1
BM277183.1
RS06078
RSC00704_1
TV01443
GPC02930_1
BG577520.1
MA03346
MHC09263_1
BXC05532_1
MHC02607_1
SC00124
MH10391
TS03183
CN477827.1
GP00336
GR978899.1
BE239171.1
TMC00570_1
Associated_featureWBsf654939
WBsf658581
Experimental_infoRNAi_resultWBRNAi00076416Inferred_automaticallyRNAi_primary
WBRNAi00027816Inferred_automaticallyRNAi_primary
WBRNAi00014849Inferred_automaticallyRNAi_primary
WBRNAi00006569Inferred_automaticallyRNAi_primary
WBRNAi00047133Inferred_automaticallyRNAi_primary
WBRNAi00022707Inferred_automaticallyRNAi_primary
WBRNAi00090595Inferred_automaticallyRNAi_primary
WBRNAi00022708Inferred_automaticallyRNAi_primary
Expr_patternExpr1991
Expr1024208
Expr1030547
Expr1151001
Expr2010674
Expr2028914
Drives_constructWBCnstr00010563
WBCnstr00037224
Construct_productWBCnstr00010563
WBCnstr00037224
Microarray_results (19)
Expression_cluster (222)
SAGE_tag (15)
Interaction (142)
Map_infoMapIIIPosition-26.1239Error0.022372
PositivePositive_cloneC51B6Author_evidencePage AM
F42G9Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00002472
WBPaper00005482
WBPaper00015191
WBPaper00024704
WBPaper00026884
WBPaper00033090
WBPaper00038491
WBPaper00055090
WBPaper00065331
Remarksignal_peptide
[Page AM] Initially identified by the sequencing project. Referred to as cypB homolog by Blast analysis. cDNA clone isolated
PPIase or cyclophilin, EC 5.2.1.8
This gene has been renamed with approval of the CGC (cyp-6->cyn-6)Person_evidenceWBPerson466
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene