WormBase Tree Display for Gene: WBGene00000819

WBGene00000819 SMap: S_parent: Sequence: Y48E1B
  Identity: Version: 1
    Name: CGC_name: csp-1 Person_evidence: WBPerson576
      Sequence_name: Y48E1B.13
      Molecular_name: Y48E1B.13a
        Y48E1B.13a.1
        CE29378
        Y48E1B.13b
        CE30016
        Y48E1B.13c
        CE30017
        Y48E1B.13b.1
        Y48E1B.13c.1
      Other_name: CELE_Y48E1B.13 Accession_evidence: NDB BX284602
      Public_name: csp-1
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:21 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: csp
    Allele: WBVar02149730 Inferred_automatically: From strain object: MT16846
      WBVar00783288
      WBVar00783289
      WBVar00783290
      WBVar01499702
      WBVar00783291
      WBVar02076759
      WBVar00783292
      WBVar00783293
      WBVar01826711
      WBVar00783294
      WBVar00783295
      WBVar01826712
      WBVar00783296
      WBVar00783297
      WBVar00783298
      WBVar00783299
      WBVar00783300
      WBVar00783301
      WBVar01317413
      WBVar01317414
      WBVar00783302
      WBVar00783303
      WBVar01317415
      WBVar01317416
      WBVar00783304
      WBVar01317421
      WBVar00783305
      WBVar01317422
      WBVar00783306
      WBVar00783307
      WBVar01317423
      WBVar00783308
      WBVar01317424
      WBVar01317426
      WBVar01317427
      WBVar01498435
      WBVar01317431
      WBVar01317432
      WBVar01317442
      WBVar01317443
      WBVar01317444
      WBVar01317447
      WBVar02121737
      WBVar02120816
      WBVar01441676
      WBVar01441679
      WBVar01441681
      WBVar01441685
      WBVar02122109
      WBVar01441686
      WBVar01441687
      WBVar01441690
      WBVar01441691
      WBVar01441694
      WBVar01441695
      WBVar02120652
      WBVar00249939
      WBVar00093694
      WBVar00312461
      WBVar02121577
      WBVar01539817
      WBVar01562274
      WBVar00312462
      WBVar01562275
      WBVar01539820
      WBVar00312463
      WBVar00312464
      WBVar00008658
      WBVar00312465
      WBVar00312466
      WBVar00008663
      WBVar00312467
      WBVar01406634
      WBVar00312468
      WBVar00312469
      WBVar00312470
      WBVar00008668
      WBVar01960899
      WBVar00312471
      WBVar00312472
      WBVar00008673
      WBVar00312473
      WBVar00312474
      WBVar00008678
      WBVar01478429
      WBVar01478430
      WBVar00008683
      WBVar01473983
      WBVar01705987
      WBVar00008688
      WBVar00008693
      WBVar02121971
      WBVar00008698
      WBVar00008703
      WBVar02014529
      WBVar00008708
      WBVar00008713
      WBVar00008718
      WBVar01667082
      WBVar02124561
      WBVar00008723
      WBVar01936857
      WBVar01936858
      WBVar02007276
      WBVar00052402
      WBVar01250761
      WBVar01250765
      WBVar01250769
      WBVar01250772
      WBVar00231439
      WBVar00231440
      WBVar00231441
      WBVar00383157
      WBVar00383158
      WBVar00383159
      WBVar00383160
      WBVar00383161
      WBVar00383162
      WBVar00383163
      WBVar00383164
      WBVar00383165
      WBVar00383166
      WBVar00383167
      WBVar01642801
      WBVar01642802
      WBVar02085057
      WBVar01642804
      WBVar01642805
      WBVar01498941
      WBVar01642806
      WBVar01642807
      WBVar01642809
      WBVar01892862
      WBVar02150673
      WBVar02150674
      WBVar00783279
      WBVar00783280
      WBVar02120959
      WBVar00783281
      WBVar00783282
      WBVar00106648
      WBVar00783283
      WBVar00106649
      WBVar00783284
      WBVar00783285
      WBVar00783286
      WBVar00783287
    Strain: WBStrain00032638
      WBStrain00027566
    RNASeq_FPKM (74)
    GO_annotation (27)
    Ortholog (42)
    Paralog: WBGene00000417 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00000820 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00000821 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: The csp-1 gene encodes, by alternative splicing, three caspase homologs that may be involved in apoptosis. Paper_evidence: WBPaper00004589
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Enables cysteine-type endopeptidase activity. Involved in several processes, including negative regulation of cellular response to manganese ion; positive regulation of apoptotic process; and positive regulation of cellular response to gamma radiation. Located in germ cell nucleus. Expressed in germ line. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; carcinoma (multiple); gastrointestinal system cancer (multiple); and prostate disease (multiple). Is an ortholog of several human genes including CASP3 (caspase 3); CASP6 (caspase 6); and CASP7 (caspase 7). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model (21)
  Molecular_info: Corresponding_CDS: Y48E1B.13a
      Y48E1B.13b
      Y48E1B.13c
    Corresponding_CDS_history: Y48E1B.13:wp61
      Y48E1B.13:wp63
    Corresponding_transcript: Y48E1B.13a.1
      Y48E1B.13b.1
      Y48E1B.13c.1
    Other_sequence: AF088285
      CN477275.1
      BM01125
      CN478291.1
      MJ04766
      MP01623
    Associated_feature: WBsf990465
  Experimental_info: RNAi_result: WBRNAi00097834 Inferred_automatically: RNAi_primary
      WBRNAi00056914 Inferred_automatically: RNAi_primary
      WBRNAi00097835 Inferred_automatically: RNAi_primary
      WBRNAi00027848 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr10790
      Expr1019311
      Expr1160361
      Expr2010557
      Expr2028797
    Construct_product: WBCnstr00017125
      WBCnstr00017126
      WBCnstr00017127
      WBCnstr00017128
      WBCnstr00017129
      WBCnstr00017130
      WBCnstr00020166
    Microarray_results (30)
    Expression_cluster (87)
    Interaction (65)
  Map_info: Map: II Position: 18.6394 Error: 0.056422
    Positive: Positive_clone: Y48E1B Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4842
        4806
    Pseudo_map_position
  Reference (25)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene