WormBase Tree Display for Gene: WBGene00000796
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| WBGene00000796 | Evidence | Paper_evidence | WBPaper00005857 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | C14A4 | ||||||
| Identity | Version | 2 | |||||||
| Name | CGC_name | crn-3 | Person_evidence | WBPerson1606 | |||||
| Sequence_name | C14A4.4 | ||||||||
| Molecular_name | C14A4.4a | ||||||||
| C14A4.4a.1 | |||||||||
| CE02145 | |||||||||
| C14A4.4b | |||||||||
| CE51406 | |||||||||
| C14A4.4b.1 | |||||||||
| Other_name | exos-10 | Person_evidence | WBPerson699 | ||||||
| WBPerson6229 | |||||||||
| CELE_C14A4.4 | Accession_evidence | NDB | BX284602 | ||||||
| Public_name | crn-3 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:21 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 04 Jun 2007 15:54:19 | WBPerson2970 | Name_change | Other_name | exos-10 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | crn | ||||||||
| Allele (78) | |||||||||
| Strain | WBStrain00036816 | ||||||||
| WBStrain00007421 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (37) | |||||||||
| Contained_in_operon | CEOP2496 | ||||||||
| Ortholog (39) | |||||||||
| Paralog | WBGene00013256 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
| WBGene00015680 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | crn-3 encodes a cell death-related nuclease, homologous to the 100 kDa polymyositis/scleroderma autoantigen (PM/Scl-100), that is required for normal levels of DNA degradation during apoptosis; PM/Scl-100 is a ribonuclease component of the multiexonuclease exosome complex, which processes or degrades several types of RNAs in yeast; crn-3(RNAi) animals show retarded growth and a low penetrance of embryonic lethality; CRN-3 promotes both DNA degradation and cell corpse engulfment, in a partially redundant pathway that includes CRN-2 but is parallel to CPS-6; CRN-3 is predicted to be mitochondrial. | Paper_evidence | WBPaper00004424 | |||||
| WBPaper00005857 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable 3'-5'-RNA exonuclease activity and single-stranded RNA binding activity. Involved in apoptotic DNA fragmentation and apoptotic cell clearance. Predicted to be located in nucleolus. Predicted to be part of nuclear exosome (RNase complex). Is an ortholog of human EXOSC10 (exosome component 10). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | C14A4.4a | |||||||
| C14A4.4b | |||||||||
| Corresponding_CDS_history | C14A4.4b:wp252 | ||||||||
| Corresponding_transcript | C14A4.4a.1 | ||||||||
| C14A4.4b.1 | |||||||||
| Other_sequence (17) | |||||||||
| Associated_feature | WBsf658150 | ||||||||
| WBsf222034 | |||||||||
| Experimental_info | RNAi_result (11) | ||||||||
| Expr_pattern | Expr16396 | ||||||||
| Expr1026985 | |||||||||
| Expr1030495 | |||||||||
| Expr1144539 | |||||||||
| Expr2010538 | |||||||||
| Expr2028778 | |||||||||
| Drives_construct | WBCnstr00037270 | ||||||||
| WBCnstr00042997 | |||||||||
| Construct_product | WBCnstr00037270 | ||||||||
| WBCnstr00042997 | |||||||||
| Microarray_results (29) | |||||||||
| Expression_cluster (121) | |||||||||
| SAGE_tag (15) | |||||||||
| Interaction (224) | |||||||||
| WBProcess | WBbiopr:00000014 | ||||||||
| WBbiopr:00000103 | |||||||||
| Map_info | Map | II | Position | 3.11949 | Error | 0.000279 | |||
| Positive | Positive_clone | C14A4 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00005857 | ||||||||
| WBPaper00006283 | |||||||||
| WBPaper00019408 | |||||||||
| WBPaper00027291 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00048226 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00057242 | |||||||||
| WBPaper00065012 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
