WormBase Tree Display for Gene: WBGene00000786
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| WBGene00000786 | SMap | S_parent | Sequence | C25B8 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | cpr-6 | |||||||
| Sequence_name | C25B8.3 | ||||||||
| Molecular_name | C25B8.3 | ||||||||
| C25B8.3.1 | |||||||||
| CE04078 | |||||||||
| Other_name | CELE_C25B8.3 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | cpr-6 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:21 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | cpr | ||||||||
| Allele (38) | |||||||||
| Legacy_information | [C.elegansII] pk91 : Tc1 insertion, no known phenotype. Encodes protein with significant similarity to proteases of Cathepsin B family (EST cm01a5). [IA] | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00046005 | ||||||||
| 00046006 | |||||||||
| 00046007 | |||||||||
| 00046008 | |||||||||
| 00046009 | |||||||||
| 00046010 | |||||||||
| 00046011 | |||||||||
| 00046012 | |||||||||
| 00107792 | |||||||||
| 00107793 | |||||||||
| Ortholog (35) | |||||||||
| Paralog (28) | |||||||||
| Structured_description | Automated_description | Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Located in lysosome. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease of the nervous system (multiple); carcinoma (multiple); and type 2 diabetes mellitus. Is an ortholog of human CTSB (cathepsin B). | Paper_evidence | WBPaper00065943 | |||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:9351 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2527) | ||||
| DOID:11054 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2527) | ||||||
| DOID:2671 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2527) | ||||||
| DOID:9352 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2527) | ||||||
| DOID:2377 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2527) | ||||||
| DOID:10941 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2527) | ||||||
| DOID:12842 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2527) | ||||||
| DOID:3068 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2527) | ||||||
| DOID:4914 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2527) | ||||||
| DOID:1612 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2527) | ||||||
| Molecular_info | Corresponding_CDS | C25B8.3 | |||||||
| Corresponding_CDS_history | C25B8.3b:wp271 | ||||||||
| C25B8.3c:wp271 | |||||||||
| Corresponding_transcript | C25B8.3.1 | ||||||||
| Other_sequence (548) | |||||||||
| Associated_feature | WBsf648237 | ||||||||
| WBsf235856 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00027664 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00076158 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00088992 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00115173 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00041163 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00086767 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00093243 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00011146 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr743 | ||||||||
| Expr1015929 | |||||||||
| Expr1030487 | |||||||||
| Expr1145192 | |||||||||
| Expr2010507 | |||||||||
| Expr2028747 | |||||||||
| Drives_construct | WBCnstr00007422 | ||||||||
| WBCnstr00037276 | |||||||||
| Construct_product | WBCnstr00007564 | ||||||||
| WBCnstr00037276 | |||||||||
| Microarray_results (33) | |||||||||
| Expression_cluster (248) | |||||||||
| Interaction (108) | |||||||||
| Map_info | Map | X | Position | -2.73949 | Error | 0.013617 | |||
| Positive | Positive_clone | C25B8 | Author_evidence | Larminie CGC | |||||
| Inferred_automatically | From sequence, transcript, pseudogene data | ||||||||
| Mapping_data | Multi_point | 4237 | |||||||
| Pseudo_map_position | |||||||||
| Reference (11) | |||||||||
| Remark | data received 11/94 | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
