WormBase Tree Display for Gene: WBGene00000786

WBGene00000786 SMap: S_parent: Sequence: C25B8
  Identity: Version: 1
    Name: CGC_name: cpr-6
      Sequence_name: C25B8.3
      Molecular_name: C25B8.3
        C25B8.3.1
        CE04078
      Other_name: CELE_C25B8.3 Accession_evidence: NDB BX284606
      Public_name: cpr-6
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:21 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: cpr
    Allele (38)
    Legacy_information: [C.elegansII] pk91 : Tc1 insertion, no known phenotype. Encodes protein with significant similarity to proteases of Cathepsin B family (EST cm01a5). [IA]
    RNASeq_FPKM (74)
    GO_annotation: 00046005
      00046006
      00046007
      00046008
      00046009
      00046010
      00046011
      00046012
      00107792
      00107793
    Ortholog: WBGene00051467 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00032114 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00152481 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00098279 Pristionchus pacificus From_analysis: OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00138247 Caenorhabditis japonica From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00222626 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g2467 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g8070 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g6798 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g17461 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g2712 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g26483 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g294 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g15523 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g23317 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g15692 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00249.g7869 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-cpr-6 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold626.g6398 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00738.g14982 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_00324 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_024615 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g01297 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g14606 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_X0191500 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrX_pilon.g19270 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00239621 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00266160 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00293292 Trichuris muris From_analysis: WormBase-Compara
      FB:FBgn0030521 Drosophila melanogaster From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-040426-2650 Danio rerio From_analysis: Hieranoid
            OMA
            OrthoFinder
            Panther
      ZFIN:ZDB-GENE-070323-1 Danio rerio From_analysis: Hieranoid
            OMA
            OrthoFinder
            Panther
      HGNC:2527 Homo sapiens From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      MGI:88561 Mus musculus From_analysis: Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      RGD:621509 Rattus norvegicus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
    Paralog (28)
    Structured_description: Automated_description: Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Located in lysosome. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease of the nervous system (multiple); carcinoma (multiple); and type 2 diabetes mellitus. Is an ortholog of human CTSB (cathepsin B). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:9351 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2527)
      DOID:11054 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2527)
      DOID:2671 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2527)
      DOID:9352 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2527)
      DOID:2377 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2527)
      DOID:10941 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2527)
      DOID:12842 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2527)
      DOID:3068 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2527)
      DOID:4914 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2527)
      DOID:1612 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2527)
  Molecular_info: Corresponding_CDS: C25B8.3
    Corresponding_CDS_history: C25B8.3b:wp271
      C25B8.3c:wp271
    Corresponding_transcript: C25B8.3.1
    Other_sequence (548)
    Associated_feature: WBsf648237
      WBsf235856
  Experimental_info: RNAi_result: WBRNAi00027664 Inferred_automatically: RNAi_primary
      WBRNAi00076158 Inferred_automatically: RNAi_primary
      WBRNAi00088992 Inferred_automatically: RNAi_primary
      WBRNAi00115173 Inferred_automatically: RNAi_primary
      WBRNAi00041163 Inferred_automatically: RNAi_primary
      WBRNAi00086767 Inferred_automatically: RNAi_primary
      WBRNAi00093243 Inferred_automatically: RNAi_primary
      WBRNAi00011146 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr743
      Expr1015929
      Expr1030487
      Expr1145192
      Expr2010507
      Expr2028747
    Drives_construct: WBCnstr00007422
      WBCnstr00037276
    Construct_product: WBCnstr00007564
      WBCnstr00037276
    Microarray_results (33)
    Expression_cluster (248)
    Interaction (108)
  Map_info: Map: X Position: -2.73949 Error: 0.013617
    Positive: Positive_clone: C25B8 Author_evidence: Larminie CGC
          Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4237
    Pseudo_map_position
  Reference (11)
  Remark: data received 11/94
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene