WormBase Tree Display for Gene: WBGene00000653

WBGene00000653 Evidence: Person_evidence: WBPerson345
      WBPerson651
  SMap: S_parent: Sequence: M195
  Identity: Version: 1
    Name: CGC_name: col-77 Person_evidence: WBPerson345
      Sequence_name: M195.1
      Molecular_name: M195.1
        M195.1.1
        CE03514
      Other_name: CELE_M195.1 Accession_evidence: NDB BX284602
      Public_name: col-77
    DB_info: Database: AceView gene 2I648
        WormQTL gene WBGene00000653
        WormFlux gene WBGene00000653
        NDB locus_tag CELE_M195.1
        Panther gene CAEEL|WormBase=WBGene00000653|UniProtKB=Q21562
          family PTHR24637
        NCBI gene 174336
        RefSeq protein NM_063358.5
        TrEMBL UniProtAcc Q21562
        UniProt_GCRP UniProtAcc Q21562
        OMIM gene 120240
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:21 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: col
    Allele (19)
    RNASeq_FPKM (74)
    GO_annotation: 00072106
      00072107
      00072108
      00107650
    Ortholog (29)
    Paralog (163)
    Structured_description: Concise_description: col-77 encodes a cuticular collagen; as loss of col-77 activity via RNAi screens results in no obvious defects, the precise role of col-77 in C. elegans development and/or behavior is not yet known. Paper_evidence: WBPaper00004651
            WBPaper00005654
            WBPaper00024497
            WBPaper00025054
          Curator_confirmed: WBPerson1843
          Date_last_updated: 19 Jan 2007 00:00:00
      Automated_description: Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. Human ortholog(s) of this gene implicated in Bethlem myopathy and Ullrich congenital muscular dystrophy. Is an ortholog of human COL6A2 (collagen type VI alpha 2 chain). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0050663 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2212)
      DOID:0050558 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2212)
  Molecular_info: Corresponding_CDS: M195.1
    Corresponding_transcript: M195.1.1
    Other_sequence (111)
    Associated_feature: WBsf650316
      WBsf650317
      WBsf988714
      WBsf1012684
      WBsf223486
      WBsf223487
  Experimental_info: RNAi_result: WBRNAi00017242 Inferred_automatically: RNAi_primary
      WBRNAi00098897 Inferred_automatically: RNAi_primary
      WBRNAi00098899 Inferred_automatically: RNAi_primary
      WBRNAi00091337 Inferred_automatically: RNAi_primary
      WBRNAi00098900 Inferred_automatically: RNAi_primary
      WBRNAi00007445 Inferred_automatically: RNAi_primary
      WBRNAi00051011 Inferred_automatically: RNAi_primary
      WBRNAi00034471 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1023714
      Expr1030384
      Expr1154719
      Expr2010424
      Expr2028665
    Drives_construct: WBCnstr00037397
    Construct_product: WBCnstr00037397
    Microarray_results (16)
    Expression_cluster (335)
    Interaction (133)
  Map_info: Map: II Position: 0.76576 Error: 0.000711
    Positive: Positive_clone: M195 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00031002
    WBPaper00038491
    WBPaper00055090
    WBPaper00059378
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene