WormBase Tree Display for Gene: WBGene00000583
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| WBGene00000583 | Evidence | Person_evidence | WBPerson651 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| WBPerson260 | |||||||||
| WBPerson385 | |||||||||
| SMap | S_parent | Sequence | C48E7 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | cof-2 | Person_evidence | WBPerson260 | |||||
| Sequence_name | C48E7.5 | ||||||||
| Molecular_name | C48E7.5 | ||||||||
| C48E7.5.1 | |||||||||
| CE36279 | |||||||||
| Other_name | col-57 | ||||||||
| ofm-2 | Person_evidence | WBPerson260 | |||||||
| CELE_C48E7.5 | Accession_evidence | NDB | BX284601 | ||||||
| Public_name | cof-2 | ||||||||
| DB_info | Database | AceView | gene | 1G827 | |||||
| WormQTL | gene | WBGene00000583 | |||||||
| WormFlux | gene | WBGene00000583 | |||||||
| NDB | locus_tag | CELE_C48E7.5 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00000583|UniProtKB=G5EBT7 | |||||||
| family | PTHR23192 | ||||||||
| NCBI | gene | 183582 | |||||||
| RefSeq | protein | NM_059403.5 | |||||||
| TrEMBL | UniProtAcc | G5EBT7 | |||||||
| UniProt_GCRP | UniProtAcc | G5EBT7 | |||||||
| OMIM | gene | 608603 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:21 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | cof | ||||||||
| Allele (28) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00010186 | ||||||||
| 00010187 | |||||||||
| 00010188 | |||||||||
| 00010189 | |||||||||
| Ortholog (50) | |||||||||
| Paralog | WBGene00006845 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00008543 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | cof-2 encodes a type II transmembrane protein containing extracellular collage-like repeats and a highly conserved olfactomedin (OLF) domain, and is homologous to human GLC1A, which when mutated leads to glaucome primary open angle (OMIM:137750); a cof-2::gfp promoter fusion is expressed in muscle cells. | Paper_evidence | WBPaper00004103 | |||||
| WBPaper00006427 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 13 Jul 2015 00:00:00 | ||||||||
| Automated_description | Predicted to be involved in signal transduction. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in lethal congenital contracture syndrome. Is an ortholog of human GLDN (gliomedin). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0060558 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:29514) | ||||
| Molecular_info | Corresponding_CDS | C48E7.5 | |||||||
| Corresponding_CDS_history | C48E7.5:wp116 | ||||||||
| Corresponding_transcript | C48E7.5.1 | ||||||||
| Other_sequence | JI166496.1 | ||||||||
| JI167173.1 | |||||||||
| Dviv_isotig26478 | |||||||||
| Oden_isotig21470 | |||||||||
| Associated_feature | WBsf643344 | ||||||||
| WBsf217778 | |||||||||
| WBsf217779 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00029947 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00042743 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00042737 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00003197 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00003196 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00042744 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr3194 | ||||||||
| Expr1014871 | |||||||||
| Expr1146734 | |||||||||
| Expr2010288 | |||||||||
| Expr2028530 | |||||||||
| Drives_construct | WBCnstr00037446 | ||||||||
| Construct_product | WBCnstr00037446 | ||||||||
| Antibody | WBAntibody00000826 | ||||||||
| Microarray_results (25) | |||||||||
| Expression_cluster (88) | |||||||||
| Interaction | WBInteraction000354025 | ||||||||
| WBInteraction000501569 | |||||||||
| Map_info | Map | I | Position | 0.885296 | Error | 0.001203 | |||
| Positive | Positive_clone | C48E7 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4841 | |||||||
| 4805 | |||||||||
| 4217 | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00006427 | ||||||||
| WBPaper00024680 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | C48E7.4 has been merged into C48E7.5 | Person_evidence | WBPerson260 | ||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
