WormBase Tree Display for Gene: WBGene00000503
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| WBGene00000503 | SMap | S_parent | Sequence | C04F6 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | cht-1 | |||||||
| Sequence_name | C04F6.3 | ||||||||
| Molecular_name | C04F6.3 | ||||||||
| C04F6.3.1 | |||||||||
| CE03923 | |||||||||
| Other_name | CHT1 | Accession_evidence | EMBL | AF026152 | |||||
| CELE_C04F6.3 | Accession_evidence | NDB | BX284606 | ||||||
| Public_name | cht-1 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:21 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | cht | ||||||||
| Allele (43) | |||||||||
| Strain | WBStrain00031429 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (21) | |||||||||
| Ortholog (78) | |||||||||
| Paralog (33) | |||||||||
| Structured_description | Concise_description | cht-1 encodes a chitinase orthologous to human chitinase-1 (OMIM:600031, mutations are associated with chitotriosidase deficiency); CHT-1 is predicted to function as an extracellular O-glycosyl hydrolase that hydrolyzes the glycosidic bond between two or more carbohydrates; in C. elegans, CHT-1 may play a role in embryogenesis, and may also be required for cuticle degradation during molting and degradation of chitin-containing pathogens as part of a host defense mechanism. | Paper_evidence | WBPaper00004651 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson1823 | |||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Enables chitinase activity. Involved in chitin catabolic process and response to fungus. Predicted to be located in extracellular region. Expressed in gonad. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); and lung disease (multiple). Is an ortholog of human CHIA (chitinase acidic). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model (30) | ||||||||
| Molecular_info | Corresponding_CDS | C04F6.3 | |||||||
| Corresponding_transcript | C04F6.3.1 | ||||||||
| Other_sequence (54) | |||||||||
| Associated_feature (13) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00039652 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00098179 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00000785 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00010142 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1834 | ||||||||
| Expr4006 | |||||||||
| Expr1026158 | |||||||||
| Expr1030298 | |||||||||
| Expr1143745 | |||||||||
| Expr2010002 | |||||||||
| Expr2028243 | |||||||||
| Drives_construct | WBCnstr00037492 | ||||||||
| Construct_product | WBCnstr00037492 | ||||||||
| Antibody | WBAntibody00000471 | ||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (333) | |||||||||
| Interaction (24) | |||||||||
| Map_info | Map | X | Position | -10.3709 | Error | 0.008165 | |||
| Positive | Positive_clone | C04F6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4219 | |||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00005166 | ||||||||
| WBPaper00033244 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00039851 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00061339 | |||||||||
| WBPaper00061511 | |||||||||
| WBPaper00064648 | |||||||||
| WBPaper00064816 | |||||||||
| WBPaper00065988 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
