WormBase Tree Display for Gene: WBGene00000484

WBGene00000484 Evidence: CGC_data_submission
  SMap: S_parent: Sequence: F38G1
  Identity: Version: 1
    Name: CGC_name: che-2 Person_evidence: WBPerson261
      Sequence_name: F38G1.1
      Molecular_name: F38G1.1
        F38G1.1.1
        CE25876
      Other_name: CELE_F38G1.1 Accession_evidence: NDB BX284606
      Public_name: che-2
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:21 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: che
    Reference_allele: WBVar00143695
    Allele (93)
    Legacy_information: e1033 : non-chemotactic to sodium ion slightly small defective osmotic avoidance defective dauer formation males impotent; no FITC uptake; ciliated neurons have abnormal stunted ultrastructure. ES2 ME0. NA1.
      See also e1033
      [C.elegansII] e1033 : non-chemotactic to sodium ion; slightly small; defective osmotic avoidance; defective dauer formation; males impotent; Dyf (no FITC uptake); ciliated neurons have abnormal stunted ultrastructure. ES2. ME0.OA5: m127, mn330mut, mn395 etc. [Lewis and Hodgkin 1977; Starich et al. 1995; DR; SP; NJ]
    Strain: WBStrain00030520
      WBStrain00030521
      WBStrain00004231
      WBStrain00006208
    RNASeq_FPKM (74)
    GO_annotation (19)
    Ortholog (39)
    Structured_description: Concise_description: che-2 encodes a protein that contains G-protein beta-like WD-40 repeats that affects chemotaxis, dauer formation, and longevity; expressed in the cilia of most ciliated sensory neurons, some head neurons, and male tail rays. Paper_evidence: WBPaper00001482
            WBPaper00001786
            WBPaper00002033
            WBPaper00003761
            WBPaper00003977
            WBPaper00004692
            WBPaper00005596
          Curator_confirmed: WBPerson48
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Involved in several processes, including dauer larval development; negative regulation of transforming growth factor beta receptor signaling pathway; and positive regulation of locomotion involved in locomotory behavior. Located in ciliary basal body and non-motile cilium. Expressed in neurons. Human ortholog(s) of this gene implicated in asphyxiating thoracic dystrophy 2. Is an ortholog of human IFT80 (intraflagellar transport 80). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0110086 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:29262)
  Molecular_info: Corresponding_CDS: F38G1.1
    Corresponding_transcript: F38G1.1.1
    Other_sequence: Acan_isotig12713
      JI226764.1
    Associated_feature: WBsf042305
      WBsf647785
      WBsf1003791
      WBsf235268
  Experimental_info: RNAi_result: WBRNAi00014580 Inferred_automatically: RNAi_primary
      WBRNAi00068042 Inferred_automatically: RNAi_primary
      WBRNAi00067404 Inferred_automatically: RNAi_primary
      WBRNAi00067940 Inferred_automatically: RNAi_primary
      WBRNAi00046733 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1157
      Expr10123
      Expr1024294
      Expr1030285
      Expr1150609
      Expr2009965
      Expr2028205
    Drives_construct (17)
    Construct_product (11)
    Microarray_results (20)
    Expression_cluster (153)
    Interaction: WBInteraction000001469
      WBInteraction000001931
      WBInteraction000001932
      WBInteraction000005618
      WBInteraction000006858
      WBInteraction000007394
      WBInteraction000007496
      WBInteraction000028616
      WBInteraction000029736
      WBInteraction000029761
      WBInteraction000126383
      WBInteraction000126436
      WBInteraction000126492
      WBInteraction000126538
      WBInteraction000127259
      WBInteraction000134524
      WBInteraction000142018
      WBInteraction000142019
      WBInteraction000149156
      WBInteraction000161296
      WBInteraction000161297
      WBInteraction000161302
      WBInteraction000165553
      WBInteraction000165554
      WBInteraction000165634
      WBInteraction000179623
      WBInteraction000185229
      WBInteraction000191513
      WBInteraction000191517
      WBInteraction000200676
      WBInteraction000202355
      WBInteraction000220159
      WBInteraction000246802
      WBInteraction000249613
      WBInteraction000253430
      WBInteraction000259820
      WBInteraction000261683
      WBInteraction000264589
      WBInteraction000265241
      WBInteraction000270633
      WBInteraction000277897
      WBInteraction000300122
      WBInteraction000300572
      WBInteraction000302995
      WBInteraction000312054
      WBInteraction000321563
      WBInteraction000339311
      WBInteraction000342201
      WBInteraction000345929
      WBInteraction000358716
      WBInteraction000361384
      WBInteraction000365668
      WBInteraction000366309
      WBInteraction000371544
      WBInteraction000386317
      WBInteraction000388887
      WBInteraction000389746
      WBInteraction000390220
      WBInteraction000393045
      WBInteraction000393937
      WBInteraction000400207
      WBInteraction000402619
      WBInteraction000418104
      WBInteraction000421031
      WBInteraction000444315
      WBInteraction000444665
      WBInteraction000446841
      WBInteraction000447311
      WBInteraction000454122
      WBInteraction000462579
      WBInteraction000475059
      WBInteraction000500288
      WBInteraction000500291
      WBInteraction000500292
      WBInteraction000500293
      WBInteraction000500294
      WBInteraction000518966
      WBInteraction000520975
      WBInteraction000542904
      WBInteraction000542917
      WBInteraction000556041
  Map_info: Map: X Position: -19.7593 Error: 0.046333
    Well_ordered
    Positive: Positive_clone: F38G1 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: 2_point: 3385
      Multi_point: 1213
        1585
        1856
        2320
        2431
        2432
        4432
      Pos_neg_data: 5455
        5461
        5466
        5470
        5474
        5478
        5482
        5486
        5490
        5494
  Reference (127)
  Remark: Sequence connection from [Fujiwara M, Katsura I]
  Method: Gene