WormBase Tree Display for Gene: WBGene00000458
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| WBGene00000458 | SMap | S_parent | Sequence | CHROMOSOME_X | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | ceh-37 | Person_evidence | WBPerson83 | |||||
| Sequence_name | C37E2.5 | ||||||||
| Molecular_name (12) | |||||||||
| Other_name | CELE_C37E2.5 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | ceh-37 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ceh | ||||||||
| Allele (260) | |||||||||
| Strain | WBStrain00003219 | ||||||||
| WBStrain00024200 | |||||||||
| WBStrain00024201 | |||||||||
| WBStrain00031536 | |||||||||
| WBStrain00048942 | |||||||||
| WBStrain00055073 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (29) | |||||||||
| Ortholog (38) | |||||||||
| Paralog (20) | |||||||||
| Structured_description | Concise_description | ceh-37 encodes one of three C. elegans proteins with an OTX-like homeodomain; however, CEH-37 lacks other domains found in OTX proteins, and the CEH-37 homeodomain is predicted to resemble the Myb domain of telomere-binding proteins; CEH-37 binds the telomeric sequence 'TTAGGC' if it is repeated at least 1.5 times, and is mainly localized to the telomere in vivo; ceh-37 mutants have a weak increase in chromosomal nondisjunction; CEH-37 is involved in specifying some aspects of the AWB olfactory neuron fate, such as expression of an AWB-specific odorant receptor and a LIM-class homeodomain protein, LIM-4; CEH-37 is expressed broadly in the early embryo, while in larvae and adults it is expressed solely in the excretory cell. | Paper_evidence | WBPaper00006000 | |||||
| WBPaper00010611 | |||||||||
| WBPaper00017043 | |||||||||
| WBPaper00023311 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson480 | |||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Enables DNA binding activity, bending and double-stranded telomeric DNA binding activity. Involved in neuron fate specification; olfactory behavior; and regulation of transcription by RNA polymerase II. Located in chromosome, telomeric region. Expressed in several structures, including ABarpaap; dorsal nerve cord; excretory cell; head muscle; and head neurons. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 7 and cone-rod dystrophy 2. Is an ortholog of human CRX (cone-rod homeobox). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0110333 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2383) | ||||
| DOID:0111005 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2383) | ||||||
| Molecular_info | Corresponding_CDS | C37E2.5a | |||||||
| C37E2.5b | |||||||||
| C37E2.5c | |||||||||
| C37E2.5d | |||||||||
| Corresponding_transcript | C37E2.5a.1 | ||||||||
| C37E2.5b.1 | |||||||||
| C37E2.5c.1 | |||||||||
| C37E2.5d.1 | |||||||||
| Other_sequence | ACC33504_1 | ||||||||
| OOC03311_1 | |||||||||
| Oden_isotig21898 | |||||||||
| JI175634.1 | |||||||||
| PPC21066_1 | |||||||||
| JI170763.1 | |||||||||
| ES564168.1 | |||||||||
| EX559356.1 | |||||||||
| Associated_feature (20) | |||||||||
| Transcription_factor | WBTranscriptionFactor000475 | ||||||||
| Experimental_info | RNAi_result | WBRNAi00107118 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00106222 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00090702 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00029643 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00042117 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00011722 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern (14) | |||||||||
| Drives_construct | WBCnstr00001666 | ||||||||
| WBCnstr00003694 | |||||||||
| WBCnstr00010926 | |||||||||
| WBCnstr00012613 | |||||||||
| WBCnstr00018499 | |||||||||
| Construct_product | WBCnstr00010870 | ||||||||
| WBCnstr00018499 | |||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (177) | |||||||||
| Interaction (79) | |||||||||
| Map_info | Map | X | Position | 16.6652 | Error | 0.001448 | |||
| Positive | Positive_clone | C37E2 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4209 | |||||||
| 4254 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (34) | |||||||||
| Remark | [Burglin T] registered gene name | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
