WormBase Tree Display for Gene: WBGene00000246
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WBGene00000246 | Evidence | Paper_evidence | WBPaper00005566 | ||||||
---|---|---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | M7 | ||||||
Identity | Version | 1 | |||||||
Name | CGC_name | bcc-1 | Person_evidence | WBPerson320 | |||||
Sequence_name | M7.3 | ||||||||
Molecular_name | M7.3 | ||||||||
M7.3.1 | |||||||||
CE42605 | |||||||||
Other_name | CELE_M7.3 | Accession_evidence | NDB | BX284604 | |||||
Public_name | bcc-1 | ||||||||
DB_info | Database | AceView | gene | 4L852 | |||||
WormQTL | gene | WBGene00000246 | |||||||
WormFlux | gene | WBGene00000246 | |||||||
NDB | locus_tag | CELE_M7.3 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00000246|UniProtKB=Q21593 | |||||||
family | PTHR10627 | ||||||||
NCBI | gene | 178008 | |||||||
RefSeq | protein | NM_069666.6 | |||||||
TREEFAM | TREEFAM_ID | TF323767 | |||||||
TrEMBL | UniProtAcc | Q21593 | |||||||
UniProt_GCRP | UniProtAcc | Q21593 | |||||||
OMIM | gene | 614295 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | bcc | ||||||||
Allele (68) | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation | 00072167 | ||||||||
00072168 | |||||||||
00072169 | |||||||||
00107106 | |||||||||
00107107 | |||||||||
Ortholog (37) | |||||||||
Paralog (2) | |||||||||
Structured_description | Concise_description | bcc-1 encodes a homolog of Drosophila and vertebrate Bicaudal C (BICC) that contains KH RNA-binding domains, a serine-rich region, and a SAM (sterile alpha motif) domain; by homology, BCC-1 is predicted to function as a cytoplasmic RNA-binding protein that is required for translational regulation and/or mRNA stability during embryonic or germline development; however, as loss of bcc-1 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of BCC-1 in C. elegans development and/or behavior is not yet known. | Paper_evidence | WBPaper00005566 | |||||
WBPaper00005654 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
Automated_description | Predicted to enable RNA binding activity. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in diffuse cystic renal dysplasia. Is an ortholog of human BICC1 (BicC family RNA binding protein 1). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:0111682 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:19351) | ||||
Molecular_info | Corresponding_CDS | M7.3 | |||||||
Corresponding_CDS_history | M7.3:wp52 | ||||||||
M7.3:wp191 | |||||||||
Corresponding_transcript | M7.3.1 | ||||||||
Other_sequence (17) | |||||||||
Experimental_info | RNAi_result (12) | ||||||||
Expr_pattern | Expr11039 | ||||||||
Expr1019741 | |||||||||
Expr1154759 | |||||||||
Expr2009580 | |||||||||
Expr2027817 | |||||||||
Drives_construct | WBCnstr00017868 | ||||||||
WBCnstr00037633 | |||||||||
Construct_product | WBCnstr00037633 | ||||||||
Microarray_results (25) | |||||||||
Expression_cluster (120) | |||||||||
Interaction (32) | |||||||||
Map_info | Map | IV | Position | 4.84895 | Error | 0.004289 | |||
Positive | Positive_clone | M7 | Inferred_automatically | From CDS info | |||||
From sequence, transcript, pseudogene data | |||||||||
Pseudo_map_position | |||||||||
Reference | WBPaper00005566 | ||||||||
WBPaper00038491 | |||||||||
WBPaper00041206 | |||||||||
WBPaper00042458 | |||||||||
WBPaper00042742 | |||||||||
WBPaper00055090 | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |