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WormBase Tree Display for Gene: WBGene00000246

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Name Class

WBGene00000246EvidencePaper_evidenceWBPaper00005566
SMapS_parentSequenceM7
IdentityVersion1
NameCGC_namebcc-1Person_evidenceWBPerson320
Sequence_nameM7.3
Molecular_nameM7.3
M7.3.1
CE42605
Other_nameCELE_M7.3Accession_evidenceNDBBX284604
Public_namebcc-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:20WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classbcc
Allele (68)
RNASeq_FPKM (74)
GO_annotation00072167
00072168
00072169
00107106
00107107
Ortholog (37)
ParalogWBGene00001597Caenorhabditis elegansFrom_analysisPanther
WBGene00007463Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionbcc-1 encodes a homolog of Drosophila and vertebrate Bicaudal C (BICC) that contains KH RNA-binding domains, a serine-rich region, and a SAM (sterile alpha motif) domain; by homology, BCC-1 is predicted to function as a cytoplasmic RNA-binding protein that is required for translational regulation and/or mRNA stability during embryonic or germline development; however, as loss of bcc-1 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of BCC-1 in C. elegans development and/or behavior is not yet known.Paper_evidenceWBPaper00005566
WBPaper00005654
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable RNA binding activity. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in diffuse cystic renal dysplasia. Is an ortholog of human BICC1 (BicC family RNA binding protein 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0111682Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:19351)
Molecular_infoCorresponding_CDSM7.3
Corresponding_CDS_historyM7.3:wp52
M7.3:wp191
Corresponding_transcriptM7.3.1
Other_sequence (17)
Experimental_infoRNAi_result (12)
Expr_patternExpr11039
Expr1019741
Expr1154759
Expr2009580
Expr2027817
Drives_constructWBCnstr00017868
WBCnstr00037633
Construct_productWBCnstr00037633
Microarray_results (25)
Expression_cluster (120)
Interaction (32)
Map_infoMapIVPosition4.84895Error0.004289
PositivePositive_cloneM7Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00005566
WBPaper00038491
WBPaper00041206
WBPaper00042458
WBPaper00042742
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene