WormBase Tree Display for Gene: WBGene00000151
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| WBGene00000151 | SMap | S_parent | Sequence | T05H10 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | apn-1 | |||||||
| Sequence_name | T05H10.2 | ||||||||
| Molecular_name | T05H10.2 | ||||||||
| T05H10.2.1 | |||||||||
| CE28953 | |||||||||
| Other_name | CeAPN1 | Accession_evidence | EMBL | U40707 | |||||
| CELE_T05H10.2 | Accession_evidence | NDB | BX284602 | ||||||
| Public_name | apn-1 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | apn | ||||||||
| Allele (23) | |||||||||
| Legacy_information | apn for APurinic/apyrimidinic endoNuclease. cDNA identified, encodes 278 aa predicted protein with 41% identity to ScApn1, 45% identity to E.coli EndoIV. Predicted gene T05H10.2. | ||||||||
| Strain | WBStrain00051056 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (23) | |||||||||
| Contained_in_operon | CEOP2332 | ||||||||
| Ortholog (26) | |||||||||
| Structured_description | Concise_description | apn-1 encodes a member of the AP (apurinic or apyrimidinic) endonuclease (endo IV) family of DNA repair enzymes; apn-1 activity is essential for DNA repair and maintaining genome integrity; APN-1 exhibits DNA repair activities including nucleotide incision and 3'- to 5'exonuclease activity; expression of an apn-1 cDNA can complement an apn1apn2tpp1 triply mutant S. cerevisiae strain deficient in DNA repair. | Paper_evidence | WBPaper00041347 | |||||
| WBPaper00035564 | |||||||||
| WBPaper00025201 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson1843 | |||||||||
| Date_last_updated | 04 Jun 2014 00:00:00 | ||||||||
| Automated_description | Enables 3'-tyrosyl-DNA phosphodiesterase activity; DNA-(apurinic or apyrimidinic site) endonuclease activity; and double-stranded DNA 3'-5' DNA exonuclease activity. Involved in base-excision repair. Located in nucleus. Expressed in hermaphrodite gonad and male gonad. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | T05H10.2 | |||||||
| Corresponding_CDS_history | T05H10.2:wp61 | ||||||||
| Corresponding_transcript | T05H10.2.1 | ||||||||
| Other_sequence (36) | |||||||||
| Associated_feature | WBsf221674 | ||||||||
| WBsf221675 | |||||||||
| WBsf221676 | |||||||||
| Experimental_info | RNAi_result (22) | ||||||||
| Expr_pattern | Expr12287 | ||||||||
| Expr14297 | |||||||||
| Expr1020784 | |||||||||
| Expr1030083 | |||||||||
| Expr1156189 | |||||||||
| Expr2009363 | |||||||||
| Expr2027599 | |||||||||
| Drives_construct | WBCnstr00037700 | ||||||||
| Construct_product | WBCnstr00037700 | ||||||||
| Microarray_results (16) | |||||||||
| Expression_cluster (109) | |||||||||
| SAGE_tag (13) | |||||||||
| Interaction (97) | |||||||||
| Map_info | Map | II | Position | 0.657767 | Error | 0.001177 | |||
| Positive | Positive_clone | T05H10 | Author_evidence | Masson JY | |||||
| Inferred_automatically | From sequence, transcript, pseudogene data | ||||||||
| Pseudo_map_position | |||||||||
| Reference (22) | |||||||||
| Remark | Data extracted from Masson et al. 1996 | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
