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WormBase Tree Display for Gene: WBGene00000114

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Name Class

WBGene00000114SMapS_parentSequenceF13D12
IdentityVersion1
NameCGC_namealh-8Person_evidenceWBPerson651
Sequence_nameF13D12.4
Molecular_nameF13D12.4a
F13D12.4a.1
CE02183
F13D12.4b
CE36262
F13D12.4b.1
Other_nameCELE_F13D12.4Accession_evidenceNDBBX284602
Public_namealh-8
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:20WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classalh
Allele (41)
StrainWBStrain00040157
WBStrain00051090
RNASeq_FPKM (74)
GO_annotation (20)
Ortholog (36)
Paralog (11)
Structured_descriptionConcise_descriptionalh-8 is orthologous to the human gene METHYLMALONATE-SEMIALDEHYDE DEHYDROGENASE (ALDH6A1; OMIM:603178), which when mutated leads to MMSDH deficiency.Curator_confirmedWBPerson1823
WBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable malonate-semialdehyde dehydrogenase (acetylating) activity and methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity. Predicted to be involved in thymine catabolic process and valine catabolic process. Located in mitochondrion. Is an ortholog of human ALDH6A1 (aldehyde dehydrogenase 6 family member A1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF13D12.4a
F13D12.4b
Corresponding_transcriptF13D12.4a.1
F13D12.4b.1
Other_sequence (168)
Associated_featureWBsf644715
WBsf644716
WBsf658271
WBsf658272
WBsf981293
WBsf989871
WBsf222186
WBsf222187
WBsf222188
WBsf222189
Experimental_infoRNAi_resultWBRNAi00044501Inferred_automaticallyRNAi_primary
WBRNAi00030884Inferred_automaticallyRNAi_primary
WBRNAi00013215Inferred_automaticallyRNAi_primary
WBRNAi00097981Inferred_automaticallyRNAi_primary
Expr_patternExpr9518
Expr1024671
Expr1030061
Expr1148451
Expr2009310
Expr2027546
Drives_constructWBCnstr00037722
Construct_productWBCnstr00014083
WBCnstr00037722
Microarray_results (45)
Expression_cluster (183)
SAGE_tagSAGE:aagaagctcgStrandSense
Unambiguously_mapped
SAGE:tctctcttgaStrandAntisense
SAGE:ttcaaacttcStrandSense
Unambiguously_mapped
SAGE:cattgttgacgggtcagStrandAntisense
Interaction (76)
Map_infoMapIIPosition4.01627Error0.005159
PositivePositive_cloneF13D12Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00038444
WBPaper00038491
WBPaper00042257
WBPaper00049812
WBPaper00049828
WBPaper00055090
WBPaper00064263
WBPaper00065140
WBPaper00065288
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene